Search Results - "XIAOQI LIU"

Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer Treatment by Liu, Xiaoqi

“…Abstract Polo-like kinases (Plks) are a family of serine-threonine kinases that regulate multiple intracellular processes including DNA replication, mitosis,…”
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Plk1 Inhibitors in Cancer Therapy: From Laboratory to Clinics by Gutteridge, Rosie Elizabeth Ann, Ndiaye, Mary Ann, Liu, Xiaoqi, Ahmad, Nihal

“…Polo-like kinase 1 (Plk1) overexpression has been shown to occur in a wide range of tumors, prompting research and development of Plk1 inhibitors as a means of…”
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Negatively charged nanoporous membrane for a dendrite-free alkaline zinc-based flow battery with long cycle life by Yuan, Zhizhang, Liu, Xiaoqi, Xu, Wenbin, Duan, Yinqi, Zhang, Huamin, Li, Xianfeng

“…Alkaline zinc-based flow batteries are regarded to be among the best choices for electric energy storage. Nevertheless, application is challenged by the issue…”
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Fine-tuning Pre-trained Convolutional Neural Networks for Gastric Precancerous Disease Classification on Magnification Narrow-band Imaging Images by Liu, Xiaoqi, Wang, Chengliang, Bai, Jianying, Liao, Guobin

“…Gastric cancer(GC) is the fourth leading cause of cancer death worldwide. To prevent the occurrence of advanced GCs, there is a need for immediate detection…”
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Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases by Kanwal, Rajnee, Datt, Manish, Liu, Xiaoqi, Gupta, Sanjay

“…Methylation of DNA and histone proteins are mutually involved in the epigenetic regulation of gene expression mediated by DNA methyltransferases (DNMTs) and…”
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Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness by Yue, Shuhua, Li, Junjie, Lee, Seung-Young, Lee, Hyeon Jeong, Shao, Tian, Song, Bing, Cheng, Liang, Masterson, Timothy A., Liu, Xiaoqi, Ratliff, Timothy L., Cheng, Ji-Xin

“…Altered lipid metabolism is increasingly recognized as a signature of cancer cells. Enabled by label-free Raman spectromicroscopy, we performed quantitative…”
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The Role of Polo-like Kinase 1 in Carcinogenesis: Cause or Consequence? by CHOLEWA, Brian D, XIAOQI LIU, AHMAD, Nihal

“…Polo-like kinase 1 (Plk1) is a well-established mitotic regulator with a diverse range of biologic functions continually being identified throughout the cell…”
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RNA-Seq profiling of circular RNA in human lung adenocarcinoma and squamous cell carcinoma by Wang, Chengdi, Tan, Shuangyan, Liu, Wen-Rong, Lei, Qian, Qiao, Wenliang, Wu, Yangping, Liu, Xiaoqi, Cheng, Wei, Wei, Yu-Quan, Peng, Yong, Li, Weimin

“…Emerging evidences demonstrate that circular RNAs (circRNAs) are abnormally expressed in tumors and could serve as prognostic markers for cancers. However, the…”
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Inhibition of enhancer of zeste homolog 2 (EZH2) overcomes enzalutamide resistance in castration-resistant prostate cancer by Bai, Yunfeng, Zhang, Zhuangzhuang, Cheng, Lijun, Wang, Ruixin, Chen, Xiaoliang, Kong, Yifan, Feng, Feng, Ahmad, Nihal, Li, Lang, Liu, Xiaoqi

“…Enzalutamide, approved by the United States Food and Drug Administration in 2018 for the management of metastatic castration-resistant prostate cancer (CRPC),…”
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Difference in Rumor Dissemination and Debunking Before and After the Relaxation of COVID-19 Prevention and Control Measures in China: Infodemiology Study by Liu, Xiaoqi, Hu, Qingyuan, Wang, Jie, Wu, Xusheng, Hu, Dehua

“…The information epidemic emerged along with the COVID-19 pandemic. While controlling the spread of COVID-19, the secondary harm of epidemic rumors to social…”
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Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity by Bi, Pengpeng, Shan, Tizhong, Liu, Weiyi, Yue, Feng, Yang, Xin, Liang, Xin-Rong, Wang, Jinghua, Li, Jie, Carlesso, Nadia, Liu, Xiaoqi, Kuang, Shihuan

“…Notch signaling is shown to regulate the browning of adipocytes and whole-body energy expenditure, with inhibition leading to protection from diet-induced…”
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Enhancement of Vindoline and Catharanthine Accumulation, Antioxidant Enzymes Activities, and Gene Expression Levels in Catharanthus roseus Leaves by Chitooligosaccharides Elicitation by Tang, Wenzhu, Liu, Xiaoqi, He, Yuning, Yang, Fan

“…(L.) G. Don is a plant belonging to the genus of the family. It contains more than one hundred alkaloids, of which some exhibit significant pharmacological…”
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p300/CBP inhibition enhances the efficacy of programmed death-ligand 1 blockade treatment in prostate cancer by Liu, Jinghui, He, Daheng, Cheng, Lijun, Huang, Changkun, Zhang, Yanquan, Rao, Xiongjian, Kong, Yifan, Li, Chaohao, Zhang, Zhuangzhuang, Liu, Jinpeng, Jones, Karrie, Napier, Dana, Lee, Eun Y., Wang, Chi, Liu, Xiaoqi

“…Blockade of programmed death-ligand 1 (PD-L1) by therapeutic antibodies has shown to be a promising strategy in cancer therapy, yet clinical response in many…”
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Epigenetic regulation of prostate cancer by Wang, Ruixin, Liu, Xiaoqi

“…Prostate cancer is (PCa) the second leading cause of cancer death in males in the United State, with 174,650 new cases and 31,620 deaths estimated in 2019. It…”
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Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC) by Kong, Yifan, Cheng, Lijun, Mao, Fengyi, Zhang, Zhuangzhuang, Zhang, Yanquan, Farah, Elia, Bosler, Jacob, Bai, Yunfeng, Ahmad, Nihal, Kuang, Shihuan, Li, Lang, Liu, Xiaoqi

“…Enzalutamide, a nonsteroidal second-generation antiandrogen, has been recently approved for the management of castration-resistant prostate cancer (CRPC)…”
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Hypoxia promotes satellite cell self-renewal and enhances the efficiency of myoblast transplantation by Liu, Weiyi, Wen, Yefei, Bi, Pengpeng, Lai, Xinsheng, Liu, X Shawn, Liu, Xiaoqi, Kuang, Shihuan

“…Microenvironmental oxygen (O(2)) regulates stem cell activity, and a hypoxic niche with low oxygen levels has been reported in multiple stem cell types…”
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Delving into the Heterogeneity of Different Breast Cancer Subtypes and the Prognostic Models Utilizing scRNA-Seq and Bulk RNA-Seq by Xu, Jieyun, Qin, Shijie, Yi, Yunmeng, Gao, Hanyu, Liu, Xiaoqi, Ma, Fei, Guan, Miao

“…Background: Breast cancer (BC) is the most common malignancy in women with high heterogeneity. The heterogeneity of cancer cells from different BC subtypes has…”
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Conditional Loss of Pten in Myogenic Progenitors Leads to Postnatal Skeletal Muscle Hypertrophy but Age-Dependent Exhaustion of Satellite Cells by Yue, Feng, Bi, Pengpeng, Wang, Chao, Li, Jie, Liu, Xiaoqi, Kuang, Shihuan

“…Skeletal muscle stem cells (satellite cells [SCs]) are normally maintained in a quiescent (G0) state. Muscle injury not only activates SCs locally, but also…”
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Consensus cluster analysis of apoptosis-related genes in patients with osteoarthritis and their correlation with immune cell infiltration by Yu, Enming, Zhang, Mingshu, Xu, Gongping, Liu, Xiaoqi, Yan, Jinglong

“…BackgroundOsteoarthritis (OA) progression involves multiple factors, including cartilage erosion as the basic pathological mechanism of degeneration, and is…”
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Plk1 inhibition enhances the efficacy of androgen signaling blockade in castration-resistant prostate cancer by Zhang, Zhe, Hou, Xianzeng, Shao, Chen, Li, Junjie, Cheng, Ji-Xin, Kuang, Shihuan, Ahmad, Nihal, Ratliff, Timothy, Liu, Xiaoqi

“…Prostate cancer is thought to be driven by oxidative stress, lipid metabolism, androgen receptor (AR) signaling, and activation of the PI3K-AKT-mTOR pathway,…”
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