Search Results - "XIAOPING QI"
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Handling performance analysis and optimization of a vehicle with considering the influence of steering shaft parameters
Published in Journal of mechanical science and technology (01-02-2023)“…The structure of a steering system plays an important role in the vehicle’s handling performance. Considering the convenience of changing the structural…”
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Position design of the trailing arm bushing on torsion beam suspension accounting for vehicle transient handling performance and uncertainties
Published in Advances in mechanical engineering (01-09-2023)“…The bushing of the trailing arm on torsion beam suspension plays a pivotal role in vehicle dynamic behavior. In this paper, the connection between bushing…”
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Study of the influence of universal gearing of steering system on vehicle handling stability
Published in Science progress (1916) (01-07-2023)“…The handling stability of a vehicle is a crucial performance aspect. In this study, the focus is on investigating the impact of the universal gearing of the…”
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Study of Suspension Parameters Matching to Enhance Vehicle Ride Comfort on Bump Road
Published in Shock and vibration (2021)“…In this study, the parameters of the MacPherson front suspension and the E-type multilink rear suspension are matched to enhance the vehicle ride comfort on…”
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Spatial and temporal VEGF receptor intracellular trafficking in microvascular and macrovascular endothelial cells
Published in Scientific reports (30-08-2021)“…The vascular endothelial growth factor receptors (VEGFRs) can shape the neovascular phenotype of vascular endothelial cells when translocated to the nucleus,…”
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Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy
Published in PloS one (21-02-2017)“…p62 is a scaffolding adaptor implicated in the clearance of protein aggregates by autophagy. Reactive oxygen species (ROS) can either stimulate or inhibit…”
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Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction
Published in Proceedings of the National Academy of Sciences - PNAS (17-09-2013)“…Two independent clinical studies have reported that fenofibrate, a peroxisome proliferator-activated receptor α (PPARα) agonist, has robust therapeutic effects…”
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PRMT5 is a therapeutic target in choroidal neovascularization
Published in Scientific reports (31-01-2023)“…Ocular neovascular diseases including neovascular age-related macular degeneration (nvAMD) are widespread causes of blindness. Patients’ non-responsiveness to…”
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Autophagy in the retina: a potential role in age-related macular degeneration
Published in Advances in experimental medicine and biology (01-01-2012)Get more information
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Decreased Expression of Soluble Epoxide Hydrolase Suppresses Murine Choroidal Neovascularization
Published in International journal of molecular sciences (09-12-2022)“…Neovascular or "wet" age-related macular degeneration (nAMD) is a leading cause of blindness among older adults. Choroidal neovascularization (CNV) is a major…”
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Dual-Quantum-Dots-Labeled Lateral Flow Strip Rapidly Quantifies Procalcitonin and C-reactive Protein
Published in Nanoscale research letters (01-12-2016)“…In the article, a dual-quantum-dots-labeled (dual-QDs-labeled) lateral flow strip (LFS) method was developed for the simultaneous and rapid quantitative…”
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Characterizing temporal and spatial recruitment of systemically administered RPE65-programmed bone marrow-derived cells to the retina in a mouse model of age-related macular degeneration
Published in Graefe's archive for clinical and experimental ophthalmology (01-10-2021)“…Purpose Previously, we reported that the intravenous injection of bone marrow-derived cells (BMDC) infected with lentivirus expressing the human RPE65 gene…”
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Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology
Published in Proceedings of the National Academy of Sciences - PNAS (22-10-2013)“…The aryl hydrocarbon receptor (AhR) is a nuclear receptor that regulates xenobiotic metabolism and detoxification. Herein, we report a previously undescribed…”
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Genotype and clinical phenotype characteristics of MAX germline mutation-associated pheochromocytoma/paraganglioma syndrome
Published in Frontiers in endocrinology (Lausanne) (30-08-2024)“…The aim of this study was to investigate the genotypic and clinical phenotypic characteristics of germline mutation-associated pheochromocytoma (PCC) and…”
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Mitochondrial Protein Nitration Primes Neurodegeneration in Experimental Autoimmune Encephalomyelitis
Published in The Journal of biological chemistry (20-10-2006)“…The mechanisms of axonal and neuronal degeneration causing visual and neurologic disability in multiple sclerosis are poorly understood. Here we explored the…”
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Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration
Published in Molecular therapy (05-04-2017)“…Bone marrow stem and progenitor cells can differentiate into a range of non-hematopoietic cell types, including retinal pigment epithelium (RPE)-like cells. In…”
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β‐Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment
Published in EMBO molecular medicine (01-09-2012)“…β‐Secretase (BACE1) is a major drug target for combating Alzheimer's disease (AD). Here we show that BACE1 −/− mice develop significant retinal pathology…”
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Diurnal Rhythmicity of Autophagy Is Impaired in the Diabetic Retina
Published in Cells (Basel, Switzerland) (07-04-2020)“…Retinal homeostasis is under both diurnal and circadian regulation. We sought to investigate the diurnal expression of autophagy proteins in normal rodent…”
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Mechanistic Characterization of GS-9190 (Tegobuvir), a Novel Nonnucleoside Inhibitor of Hepatitis C Virus NS5B Polymerase
Published in Antimicrobial Agents and Chemotherapy (01-09-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Efficiency and Safety of AAV-Mediated Gene Delivery of the Human ND4 Complex I Subunit in the Mouse Visual System
Published in Investigative ophthalmology & visual science (01-09-2009)“…To evaluate the efficiency and safety of AAV-mediated gene delivery of a normal human ND4 complex I subunit in the mouse visual system. A nuclear encoded human…”
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