Search Results - "XIAOJIANG CUI"

COVID-19 in cancer patients: risk, clinical features, and management by Liu, Cuiwei, Zhao, Yanxia, Okwan-Duodu, Derick, Basho, Reva, Cui, Xiaojiang

“…A novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread across the world, prompting the World Health Organization…”
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Antibody-Drug Conjugates in Breast Cancer: Current Status and Future Directions by Mark, Cynthia, Lee, Jin Sun, Cui, Xiaojiang, Yuan, Yuan

“…Antibody drug conjugates (ADCs) are novel medications that combine monoclonal antibodies with cytotoxic payloads, enabling the selective delivery of potent…”
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A Collagen-Remodeling Gene Signature Regulated by TGF-β Signaling Is Associated with Metastasis and Poor Survival in Serous Ovarian Cancer by CHEON, Dong-Joo, YUNGUANG TONG, KARLAN, Beth Y, ORSULIC, Sandra, SIM, Myung-Shin, DERING, Judy, BEREL, Dror, XIAOJIANG CUI, LESTER, Jenny, BEACH, Jessica A, TIGHIOUART, Mourad, WALTS, Ann E

“…To elucidate molecular pathways contributing to metastatic cancer progression and poor clinical outcome in serous ovarian cancer. Poor survival signatures from…”
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CDK4/6 Inhibitor Resistance in Hormone Receptor-Positive Metastatic Breast Cancer: Translational Research, Clinical Trials, and Future Directions by Lee, Jin Sun, Hackbart, Hannah, Cui, Xiaojiang, Yuan, Yuan

“…The emergence of CDK4/6 inhibitors, such as palbociclib, ribociclib, and abemaciclib, has revolutionized the treatment landscape for hormone receptor-positive…”
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Evaluation of MCF10A as a Reliable Model for Normal Human Mammary Epithelial Cells by Qu, Ying, Han, Bingchen, Yu, Yi, Yao, Weiwu, Bose, Shikha, Karlan, Beth Y, Giuliano, Armando E, Cui, Xiaojiang

“…Breast cancer is the most common cancer in women and a leading cause of cancer-related deaths for women worldwide. Various cell models have been developed to…”
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Effects of hormones and hormone therapy on breast tissue in transgender patients: a concise review by Patel, Harsh, Arruarana, Victor, Yao, Lucille, Cui, Xiaojiang, Ray, Edward

“…Purpose Hormone replacement therapy (HRT) has become a mainstay medical treatment option for management of gender dysphoria in transgender patients of both…”
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FOXC1-induced non-canonical WNT5A-MMP7 signaling regulates invasiveness in triple-negative breast cancer by Han, Bingchen, Zhou, Bo, Qu, Ying, Gao, Bowen, Xu, Yali, Chung, Stacey, Tanaka, Hisashi, Yang, Wei, Giuliano, Armando E., Cui, Xiaojiang

“…Triple-negative breast cancer (TNBC) has high rates of local recurrence and distant metastasis, partially due to its high invasiveness. The Forkhead box C1…”
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Current status of research and treatment for non-small cell lung cancer in never-smoking females by Saito, Shin, Espinoza-Mercado, Fernando, Liu, Hui, Sata, Naohiro, Cui, Xiaojiang, Soukiasian, Harmik J.

“…Lung cancer is the leading cause of cancer-related deaths worldwide with over 1 million deaths each year. The overall prognosis of lung cancer patients remains…”
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Identification of triptonide as a therapeutic agent for triple negative breast cancer treatment by Gao, Bowen, Chen, Jiongyu, Han, Bingchen, Zhang, Xinfeng, Hao, Jijun, Giuliano, Armando E., Cui, Yukun, Cui, Xiaojiang

“…Triple-negative breast cancer (TNBC) is associated with a high rate of early recurrence and distant metastasis, frequent development of therapeutic resistance,…”
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Redox Regulation in Cancer Stem Cells by Xu, Xinglian, Cui, Xiaojiang, Cheng, Ninghui, Li, Chunbao, Ding, Shijie, Zhou, Guanghong

“…Reactive oxygen species (ROS) and ROS-dependent (redox regulation) signaling pathways and transcriptional activities are thought to be critical in stem cell…”
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Hypoxia‐stimulated ATM activation regulates autophagy‐associated exosome release from cancer‐associated fibroblasts to promote cancer cell invasion by Xi, Lei, Peng, Meixi, Liu, Shuiqing, Liu, Yongcan, Wan, Xueying, Hou, Yixuan, Qin, Yilu, Yang, Liping, Chen, Shanchun, Zeng, Huan, Teng, Yong, Cui, Xiaojiang, Liu, Manran

“…Cancer‐associated fibroblasts (CAFs) as a predominant cell component in the tumour microenvironment (TME) play an essential role in tumour progression. Our…”
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A prognostic model of triple-negative breast cancer based on miR-27b-3p and node status by Shen, Songjie, Sun, Qiang, Liang, Zhiyong, Cui, Xiaojiang, Ren, Xinyu, Chen, Huan, Zhang, Xiao, Zhou, Yidong

“…Triple-negative breast cancer (TNBC) is an aggressive but heterogeneous subtype of breast cancer. This study aimed to identify and validate a prognostic…”
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A Novel Long Non‐Coding RNA lnc030 Maintains Breast Cancer Stem Cell Stemness by Stabilizing SQLE mRNA and Increasing Cholesterol Synthesis by Qin, Yilu, Hou, Yixuan, Liu, Shuiqing, Zhu, Pengpeng, Wan, Xueying, Zhao, Maojia, Peng, Meixi, Zeng, Huan, Li, Qiao, Jin, Ting, Cui, Xiaojiang, Liu, Manran

“…Cancer stem cells (CSCs) are considered the roots of cancer metastasis and recurrence (CSCs), due in part to their self‐renewal and therapy resistance…”
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FOXC1 Is a Potential Prognostic Biomarker with Functional Significance in Basal-like Breast Cancer by RAY, Partha S, JINHUA WANG, WALTER, Michael A, MARTENS, John W, RICHARDSON, Andrea L, GIULIANO, Armando E, XIAOJIANG CUI, YING QU, SIM, Myung-Shin, SHAMONKI, Jaime, BAGARIA, Sanjay P, XING YE, BINGYA LIU, ELASHOFF, David, HOON, Dave S

“…Gene expression signatures for a basal-like breast cancer (BLBC) subtype have been associated with poor clinical outcomes, but a molecular basis for this…”
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Stratification of Prognosis of Triple-Negative Breast Cancer Patients Using Combinatorial Biomarkers by Yue, Yong, Astvatsaturyan, Kristine, Cui, Xiaojiang, Zhang, Xiao, Fraass, Benedick, Bose, Shikha

“…Triple-negative breast cancer (TNBC) is highly diverse group of cancers, and generally considered an aggressive disease associated with poor survival…”
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RGCC-mediated PLK1 activity drives breast cancer lung metastasis by phosphorylating AMPKα2 to activate oxidative phosphorylation and fatty acid oxidation by Cheng, Shaojie, Wan, Xueying, Yang, Liping, Qin, Yilu, Chen, Shanchun, Liu, Yongcan, Sun, Yan, Qiu, Yuxiang, Huang, Luyi, Qin, Qizhong, Cui, Xiaojiang, Wu, Mingjun, Liu, Manran

“…More than 90% of the mortality of triple-negative breast cancer (TNBC) patients is attributed to cancer metastasis with organotropism. The lung is a frequent…”
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FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer by Han, Bingchen, Qu, Ying, Jin, Yanli, Yu, Yi, Deng, Nan, Wawrowsky, Kolja, Zhang, Xiao, Li, Na, Bose, Shikha, Wang, Qiang, Sakkiah, Sugunadevi, Abrol, Ravinder, Jensen, Tor W., Berman, Benjamin P., Tanaka, Hisashi, Johnson, Jeffrey, Gao, Bowen, Hao, Jijun, Liu, Zhenqiu, Buttyan, Ralph, Ray, Partha S., Hung, Mien-Chie, Giuliano, Armando E., Cui, Xiaojiang

“…The mesoderm- and epithelial-mesenchymal transition-associated transcription factor FOXC1 is specifically overexpressed in basal-like breast cancer (BLBC), but…”
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Personalizing breast cancer staging by the inclusion of ER, PR, and HER2 by Bagaria, Sanjay P, Ray, Partha S, Sim, Myung-Shin, Ye, Xing, Shamonki, Jaime M, Cui, Xiaojiang, Giuliano, Armando E

“…Nonanatomic factors, such as histologic grade and biomarkers, can guide breast cancer management but are not included in the current TNM staging system. To use…”
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Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases by Liu, Shuying, Umezu-Goto, Makiko, Murph, Mandi, Lu, Yiling, Liu, Wenbin, Zhang, Fan, Yu, Shuangxing, Stephens, L. Clifton, Cui, Xiaojiang, Murrow, George, Coombes, Kevin, Muller, William, Hung, Mien-Chie, Perou, Charles M., Lee, Adrian V., Fang, Xianjun, Mills, Gordon B.

“…Lysophosphatidic acid (LPA) acts through high-affinity G protein-coupled receptors to mediate a plethora of physiological and pathological activities…”
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Single protein encapsulated SN38 for tumor-targeting treatment by Yu, Changjun, Huang, Faqing, Wang, Kinsley, Liu, Mengmeng, Chow, Warren A, Ling, Xiang, Li, Fengzhi, Causey, Jason L, Huang, Xiuzhen, Cook-Wiens, Galen, Cui, Xiaojiang

“…The alkaloid camptothecin analog SN38 is a potent antineoplastic agent, but cannot be used directly for clinical application due to its poor water solubility…”
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