Search Results - "XIANGYING JIAO"
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Potent Intestinal Mucosal Barrier Enhancement of Nostoc commune Vaucher Polysaccharide Supplementation Ameliorates Acute Ulcerative Colitis in Mice Mediated by Gut Microbiota
Published in Nutrients (06-07-2023)“…Ulcerative colitis (UC) is evolving into a global burden with a substantially increasing incidence in developing countries. It is characterized by inflammation…”
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Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function
Published in Proceedings of the National Academy of Sciences - PNAS (25-09-2007)“…The recent discovery that hydrogen sulfide (H₂S) is an endogenously produced gaseous second messenger capable of modulating many physiological processes, much…”
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Implications of C1q/TNF-related protein superfamily in patients with coronary artery disease
Published in Scientific reports (21-01-2020)“…The C1q complement/TNF-related protein superfamily (CTRPs) displays differential effects on the regulation of metabolic homeostasis, governing cardiovascular…”
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TXNIP inhibition in the treatment of type 2 diabetes mellitus: design, synthesis, and biological evaluation of quinazoline derivatives
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2023)“…Thioredoxin interacting protein (TXNIP) is a potential drug target for type 2 diabetes mellitus (T2DM) treatment. A series of quinazoline derivatives were…”
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Angiotensin II type 1a receptor knockout ameliorates high-fat diet-induced cardiac dysfunction by regulating glucose and lipid metabolism
Published in Acta biochimica et biophysica Sinica (31-07-2023)“…Obesity-related cardiovascular diseases are associated with overactivation of the renin-angiotensin system (RAS). However, the underlying mechanisms remain…”
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Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress
Published in Circulation (New York, N.Y.) (20-03-2007)“…Several clinical studies have demonstrated that levels of adiponectin are significantly reduced in patients with type 2 diabetes and that adiponectin levels…”
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Endoplasmic reticulum stress caused by traumatic injury promotes cardiomyocyte apoptosis through acetylation modification of GRP78
Published in Acta biochimica et biophysica Sinica (01-01-2024)“…Cardiomyocyte apoptosis is an important cause of trauma-induced secondary cardiac injury (TISCI), in which the endoplasmic reticulum stress (ERS)-mediated…”
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Nicotine aggravates vascular adiponectin resistance via ubiquitin-mediated adiponectin receptor degradation in diabetic Apolipoprotein E knockout mouse
Published in Cell death & disease (18-05-2021)“…There is limited and discordant evidence on the role of nicotine in diabetic vascular disease. Exacerbated endothelial cell dysregulation in smokers with…”
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TXNIP aggravates cardiac fibrosis and dysfunction after myocardial infarction in mice by enhancing the TGFB1/Smad3 pathway and promoting NLRP3 inflammasome activation
Published in Acta biochimica et biophysica Sinica (25-12-2023)“…Myocardial infarction (MI) results in high mortality. The size of fibrotic scar tissue following MI is an independent predictor of MI outcomes…”
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Effect of hybrid teaching incorporating problem-based learning on student performance in pathophysiology
Published in Journal of International Medical Research (01-08-2020)“…Objective To compare the effectiveness of traditional and hybrid teaching strategies in pathophysiology and to conduct a survey of students’ opinions about the…”
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Book Review Journal Article -
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C1q/TNF-related protein 5 contributes to diabetic vascular endothelium dysfunction through promoting Nox-1 signaling
Published in Redox biology (01-07-2020)“…Dysregulated adipokine profiles contribute to the pathogenesis of diabetic cardiovascular complications. Endothelial cell (EC) dysfunction, a common…”
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Human endometrium-derived stem cell improves cardiac function after myocardial ischemic injury by enhancing angiogenesis and myocardial metabolism
Published in Stem cell research & therapy (10-06-2021)“…The human endometrium in premenopausal women is an active site of physiological angiogenesis, with regenerative cells present, suggesting that the endometrium…”
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A histone H3K9 methyltransferase Dim5 mediates repression of sorbicillinoid biosynthesis in Trichoderma reesei
Published in Microbial biotechnology (01-10-2022)“…Sorbicillinoids (also termed yellow pigment) are derived from either marine or terrestrial fungi, exhibit various biological activities and therefore show…”
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Txnip deficiency promotes β-cell proliferation in the HFD-induced obesity mouse model
Published in Endocrine Connections (29-04-2022)“…Elucidating the mechanisms of regulation of β-cell proliferation is key to understanding the pathogenesis of diabetes mellitus. Txnip is a tumor suppressor…”
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ATP protects anti-PD-1/radiation-induced cardiac dysfunction by inhibiting anti-PD-1 exacerbated cardiomyocyte apoptosis, and improving autophagic flux
Published in Heliyon (01-10-2023)“…The synergy between radiotherapy and immunotherapy in treating thoracic cancers presents a potent therapeutic advantage, yet it also carries potential risks…”
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Nitrative inactivation of thioredoxin-1 and its role in postischemic myocardial apoptosis
Published in Circulation (New York, N.Y.) (26-09-2006)“…Intracellular proteins involved in oxidative stress and apoptosis are nitrated in diseased tissues but not in normal tissues; definitive evidence to support a…”
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Variations of thioredoxin system contributes to increased susceptibility to apoptosis in cardiomyocytes of type 2 diabetic rats
Published in Acta biochimica et biophysica Sinica (01-04-2014)“…Cardiac complications are the leading cause of death in diabetes. However, the mechanism of diabetes in inducing myocardial injury and apoptosis, and whether…”
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Changes in cardiac structure and function in rats immunized by angiotensin type 1 receptor peptides
Published in Acta biochimica et biophysica Sinica (01-12-2011)“…Angiotensin II (Ang II) is known to induce cardiomyocyte hypertrophy by activating the Ang |I type 1 (AT1) recep- tor. Some studies have demonstrated that the…”
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Nitrative thioredoxin inactivation as a cause of enhanced myocardial ischemia/reperfusion injury in the aging heart
Published in Free radical biology & medicine (01-07-2007)“…Several recent studies have demonstrated that thioredoxin (Trx) is an important antiapoptotic/cytoprotective molecule. The present study was designed to…”
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