Search Results - "XIANGJUN CAI"

Pharmacokinetic, pharmacodynamic, and pharmacogenetic determinants of osteonecrosis in children with acute lymphoblastic leukemia by Kawedia, Jitesh D., Kaste, Sue C., Pei, Deqing, Panetta, John C., Cai, Xiangjun, Cheng, Cheng, Neale, Geoffrey, Howard, Scott C., Evans, William E., Pui, Ching-Hon, Relling, Mary V.

“…Osteonecrosis is a severe glucocorticoid-induced complication of acute lymphoblastic leukemia treatment. We prospectively screened children (n = 364) with…”
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Fenofibrate reduces osteonecrosis without affecting antileukemic efficacy in dexamethasone treated mice by Finch, Emily R, Payton, Monique A, Jenkins, David A, Cai, Xiangjun, Li, Lie, Karol, Seth E, Relling, Mary V, Janke, Laura J

“…Recent clinical trials in children with acute lymphoblastic leukemia (ALL) indicate that severe hypertriglyceridemia (> 1000 mg/dL) during therapy is…”
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Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model by Liu, Chengcheng, Janke, Laura J, Kawedia, Jitesh D, Ramsey, Laura B, Cai, Xiangjun, Mattano, Jr, Leonard A, Boyd, Kelli L, Funk, Amy J, Relling, Mary V

“…Osteonecrosis is a common dose-limiting toxicity of glucocorticoids. Data from clinical trials suggest that other medications can increase the risk of…”
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Purple sweet potato color ameliorates kidney damage via inhibiting oxidative stress mediated NLRP3 inflammasome activation in high fat diet mice by Shan, Qun, Zheng, Yuanlin, Lu, Jun, Zhang, Zifeng, Wu, Dongmei, Fan, Shaohua, Hu, Bin, Cai, Xiangjun, Cai, Hao, Liu, Peilong, Liu, Fan

“…•PSPC ameliorates obesity, glucose intolerance and insulin resistance induced by HFD.•PSPC reduces urine albumin and kidney tissue damage in HFD-treated…”
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Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia by Yang, Jun J., Bhojwani, Deepa, Yang, Wenjian, Cai, Xiangjun, Stocco, Gabriele, Crews, Kristine, Wang, Jinhua, Morrison, Debra, Devidas, Meenakshi, Hunger, Stephen P., Willman, Cheryl L., Raetz, Elizabeth A., Pui, Ching-hon, Evans, William E., Relling, Mary V., Carroll, William L.

“…The underlying pathways that lead to relapse in childhood acute lymphoblastic leukemia (ALL) are unknown. To comprehensively characterize the molecular…”
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Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models by Karol, Seth E, Janke, Laura J, Panetta, John C, Ramsey, Laura B, Cai, Xiangjun, Payton, Monique A, Jenkins, David A, Evans, William E, Relling, Mary V

“…Combination therapy for acute lymphoblastic leukemia (ALL) is highly effective but results in significant toxicity including osteonecrosis. Asparaginase is…”
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Asparaginase May Influence Dexamethasone Pharmacokinetics in Acute Lymphoblastic Leukemia by LEI YANG, PANETTA, John C, XIANGJUN CAI, WENJIAN YANG, DEQING PEI, CHENG CHENG, KORNEGAY, Nancy, PUI, Ching-Hon, RELLING, Mary V

“…Dexamethasone is used widely in oncology, but pharmacokinetic studies are lacking. We evaluated dexamethasone pharmacokinetics in children with acute…”
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Modified Laparoscopic Sugarbaker Repair of Parastomal Hernia With a Totally Extraperitoneal Technique by Jiang, Huiyong, Thapa, Dil Momin, Cai, Xiangjun, Ma, Chun, Wang, Mofei

“…Purpose: Many patients develop a parastomal hernia within the first 2 years of stoma formation, and even surgical repair is associated with high recurrence…”
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Endoscopic Totally Extraperitoneal Repair of Parastomal Hernia: A Case Report by Jiang, Huiyong, Thapa, Dil Momin, Ma, Chun, Cai, Xiangjun, Wang, Mofei

“…A parastomal hernia is a type of incisional hernia that occurs in abdominal integuments in the proximity of a stoma. It is a frequent late complication…”
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Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia by Ramsey, Laura B, Janke, Laura J, Payton, Monique A, Cai, Xiangjun, Paugh, Steven W, Karol, Seth E, Kamdem Kamdem, Landry, Cheng, Cheng, Williams, Richard T, Jeha, Sima, Pui, Ching-Hon, Evans, William E, Relling, Mary V

“…Osteonecrosis is one of the most common, serious, toxicities resulting from the treatment of acute lymphoblastic leukemia. In recent years, pediatric acute…”
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Alternative formulations of sorafenib for use in children by Navid, Fariba, Christensen, Robbin, Inaba, Hiroto, Li, Lie, Chen, Zhaoyuan, Cai, Xiangjun, Regel, Joshua, Baker, Sharyn D.

“…Background Sorafenib is an oral multikinase inhibitor with antiangiogenic and antitumor activity. In most cases, the commercially available 200 mg tablet is…”
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M-EDEM: A MNN-based Empirical Decomposition Ensemble Method for improved time series forecasting by Cai, Xiangjun, Li, Dagang

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Surgical treatment of celiomesenteric trunk aneurysm-7 case report by Wang, Chunxi, Cai, Xiangjun, Liang, Faqi, Chu, Futao, Chen, Gang, Duan, Zhiquan

“…The celiomesenteric trunk is a rare anomaly characterized by a common origin of the celiac axis and superior mesenteric artery from the aorta, which accounts…”
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Prediction of Spot Price of Iron Ore Based on PSR-WA-LSSVM Combined Model by Cai, Xiangjun, Luo, Shihua

“…Aiming at the problems that the existing single time series models are not accurate and robust enough when it comes to forecasting the iron ore prices and the…”
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Germline mutations in 40 cancer susceptibility genes among Chinese patients with high hereditary risk breast cancer by Li, Jun‐Yan, Jing, Ruilin, Wei, Hongyi, Wang, Minghao, Xiaowei, Qi, Liu, Haoxi, Jian, Liu, Ou, Jiang‐Hua, Jiang, Wei‐Hua, Tian, Fu‐Guo, Sheng, Yuan, Li, Heng‐Yu, Xu, Hong, Zhang, Rui‐Shan, Guan, Ai‐Hua, Liu, Ke, Jiang, Hong‐Chuan, Ren, Yu, He, Jian‐Jun, Huang, Weiwei, Liao, Ning, Cai, Xiangjun, Ming, Jia, Ling, Rui, Xu, Yan, Hu, Chun‐Yan, Zhang, Jianguo, Guo, Baoliang, Ouyang, Lizhi, Shuai, Ping, Liu, Zhenzhen, Zhong, Ling, Zeng, Zhen, Zhang, Ting, Xuan, Zhaoling, Tan, Xuanni, Liang, Junbin, Pan, Qinwen, Chen, Li, Zhang, Fan, Fan, Lin‐Jun, Zhang, Yi, Yang, Xinhua, BoLi, Jing, Chen, Chongjian, Jiang, Jun

“…Multigene panel testing of breast cancer predisposition genes have been extensively conducted in Europe and America, which is relatively rare in Asia however…”
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Overexpression of epithelial cell transforming 2 protein in colorectal carcinoma predicts a poor prognosis by Li, Yiming, Cai, Xiangjun, Chen, Bo, Gu, Hanbo, Liu, Caigang

“…Epithelial cell transforming 2 (Ect2) protein is a member of the human diffuse B-cell lymphoma family of guanine nucleotide exchange factors, which activate…”
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Effects of zoledronic acid on osteonecrosis and acute lymphoblastic leukemia treatment efficacy in preclinical models by Janke, Laura J., Kim, Jieun, Payton, Monique A., Jenkins, David A., Cai, Xiangjun, Finch, Emily R., Liu, Yiwei, Relling, Mary V., Karol, Seth E.

“…Background Osteonecrosis is a devastating side effect of acute lymphoblastic leukemia (ALL) therapy. Associations between bone density loss and osteonecrosis…”
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Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia by Liu, C, Kawedia, J D, Cheng, C, Pei, D, Fernandez, C A, Cai, X, Crews, K R, Kaste, S C, Panetta, J C, Bowman, W P, Jeha, S, Sandlund, J T, Evans, W E, Pui, C-H, Relling, M V

“…Hypersensitivity to asparaginase is common, but the differential diagnosis can be challenging and the diagnostic utility of antibody tests is unclear. We…”
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Germline mutations in 40 cancer susceptibility genes among C hinese patients with high hereditary risk breast cancer by Li, Jun‐Yan, Jing, Ruilin, Wei, Hongyi, Wang, Minghao, Xiaowei, Qi, Liu, Haoxi, Jian, Liu, Ou, Jiang‐Hua, Jiang, Wei‐Hua, Tian, Fu‐Guo, Sheng, Yuan, Li, Heng‐Yu, Xu, Hong, Zhang, Rui‐Shan, Guan, Ai‐Hua, Liu, Ke, Jiang, Hong‐Chuan, Ren, Yu, He, Jian‐Jun, Huang, Weiwei, Liao, Ning, Cai, Xiangjun, Ming, Jia, Ling, Rui, Xu, Yan, Hu, Chun‐Yan, Zhang, Jianguo, Guo, Baoliang, Ouyang, Lizhi, Shuai, Ping, Liu, Zhenzhen, Zhong, Ling, Zeng, Zhen, Zhang, Ting, Xuan, Zhaoling, Tan, Xuanni, Liang, Junbin, Pan, Qinwen, Chen, Li, Zhang, Fan, Fan, Lin‐Jun, Zhang, Yi, Yang, Xinhua, BoLi, Jing, Chen, Chongjian, Jiang, Jun

“…Multigene panel testing of breast cancer predisposition genes have been extensively conducted in Europe and America, which is relatively rare in Asia however…”
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Antileukemic Efficacy of Continuous Vs Discontinuous Dexamethasone in Murine Xenografts of Acute Lymphoblastic Leukemia by Ramsey, Laura B., Janke, Laura, Payton, Monique A., Cai, Xiangjun, Jeha, Sima, Pui, Ching-Hon, Evans, William E., Relling, Mary V.

“…As cure rates for acute lymphoblastic leukemia (ALL) have increased, toxic complications of chemotherapy have also increased. The incidence of osteonecrosis is…”
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