Search Results - "Wysokinski, Adam"

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    Clozapine Toxicity Predictor: Deep neural network model predicting clozapine toxicity and its therapeutic dose range by Wysokiński, Adam, Dreczka, Joanna

    Published in Psychiatry research (01-12-2024)
    “…Clozapine is the gold standard for treatment-resistant schizophrenia; however, its superior efficacy is accompanied by potentially serious adverse events…”
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    Journal Article
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    Serum levels of brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) in depressed patients with schizophrenia by Wysokinski, Adam

    Published in Nordic journal of psychiatry (18-05-2016)
    “…Aim: Brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) are neurotrophins-proteins that induce the survival, development, and function of…”
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    Journal Article
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    Platelet parameters (PLT, MPV, P-LCR) in patients with schizophrenia, unipolar depression and bipolar disorder by Wysokiński, Adam, Szczepocka, Ewa

    Published in Psychiatry research (30-03-2016)
    “…Abstract There are no studies comparing platelet parameters platelet parameters (platelet count (PLT), mean platelet volume (MPV) and platelet large cell ratio…”
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    Journal Article
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    Alarmins (IL-33, sST2, HMGB1, and S100B) as potential biomarkers for schizophrenia by Kozłowska, Elżbieta, Brzezińska-Błaszczyk, Ewa, Agier, Justyna, Wysokiński, Adam, Żelechowska, Paulina

    Published in Journal of psychiatric research (01-06-2021)
    “…There is growing evidence that immune/inflammatory processes are related to the etiology of schizophrenia. Danger-/damage-associated molecular patterns…”
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    Journal Article
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    Levels of triglycerides, cholesterol, LDL, HDL and glucose in patients with schizophrenia, unipolar depression and bipolar disorder by Wysokiński, Adam, Strzelecki, Dominik, Kłoszewska, Iwona

    “…Abstract Aims The aim of this study is to investigate differences in triglycerides (TGA), cholesterol (TC), HDL, LDL and glucose (FPG) levels in patients with…”
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    Journal Article
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    Red Blood Cells Parameters in Patients with Acute Schizophrenia, Unipolar Depression and Bipolar Disorder by Wysokiński, Adam, Szczepocka, Ewa

    Published in Psychiatria Danubina (01-09-2018)
    “…There are no studies comparing red blood cell parameters between patients with schizophrenia, bipolar disorder and unipolar depression. The aim of this study…”
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    Journal Article Paper
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    Fasting serum levels of neuropeptide y in patients with schizophrenia on clozapine monotherapy by Wysokinski, Adam

    Published in Clinical neuropharmacology (01-01-2015)
    “…Neuropeptide Y (NPY) is one of the hypothalamic hormones that works by increasing appetite and decreasing metabolism, leading to weight gain. We checked…”
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    Journal Article
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    Sarcosine May Induce EGF Production or Inhibit the Decline in EGF Concentrations in Patients with Chronic Schizophrenia (Results of the PULSAR Study) by Pawlak, Agnieszka, Kaczmarek, Bartosz, Wysokiński, Adam, Strzelecki, Dominik

    Published in Pharmaceuticals (Basel, Switzerland) (01-11-2023)
    “…Sarcosine (N-methylglycine), a glutamatergic modulator, reduces the primary negative symptoms of schizophrenia. These beneficial changes might be mediated by…”
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    Journal Article
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    In schizophrenia serum level of neurotrophin-3 (NT-3) is increased only if depressive symptoms are present by Arabska, Jaśmina, Łucka, Anna, Strzelecki, Dominik, Wysokiński, Adam

    Published in Neuroscience letters (25-09-2018)
    “…•We examined which (negative or depressive) symptoms affect serum neurotrophins-3 (NT-3) concentration in schizophrenia.•Level of NT-3 was measured using ELISA…”
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    Journal Article
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    Effect of clozapine dose and concentration on fasting concentration of appetite regulating peptides by Margulska, Aleksandra, Kozłowska, Elżbieta, Wysokiński, Adam

    Published in Psychiatry research (01-02-2018)
    “…The aim of this study is to analyze whether clozapine serum concentration may affect fasting serum levels of several appetite regulating peptides: CART,…”
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    Journal Article
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    The association between serum levels of TNF-α and IL-6 in schizophrenic patients and their metabolic status – A case control study by Arabska, Jaśmina, Strzelecki, Dominik, Kozłowska, Elżbieta, Brzezińska-Błaszczyk, Ewa, Wysokiński, Adam

    Published in Journal of neuroimmunology (15-10-2020)
    “…According to immunological theory of schizophrenia, dysfunctions of the immune system are linked with the pathology of schizophrenia. Among cytokines, tumor…”
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    Journal Article
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    Serum levels of TNF-alpha in patients with chronic schizophrenia during treatment augmentation with sarcosine (results of the PULSAR study) by Strzelecki, Dominik, Urban-Kowalczyk, Małgorzata, Wysokiński, Adam

    Published in Psychiatry research (01-10-2018)
    “…•No changes in TNF-alpha serum concentrations in both sarcosine and placebo groups was noted at any time point.•We observed significant improvement in negative…”
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    Journal Article
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    Neutrophil-lymphocyte ratio is increased in elderly patients with first episode depression, but not in recurrent depression by Arabska, Jaśmina, Łucka, Anna, Magierski, Radosław, Sobów, Tomasz, Wysokiński, Adam

    Published in Psychiatry research (01-05-2018)
    “…Association between inflammation and depression, especially in elderly patients, leads to conclusions about their shared influence on risk of cardiovascular…”
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    Journal Article
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    Serum Levels and in vitro CX3CL1 (Fractalkine), CXCL8, and IL-10 Synthesis in Phytohemaglutinin-Stimulated and Non-stimulated Peripheral Blood Mononuclear Cells in Subjects With Schizophrenia by Arabska, Jaśmina, Wysokiński, Adam, Brzezińska-Błaszczyk, Ewa, Kozłowska, Elżbieta

    Published in Frontiers in psychiatry (17-06-2022)
    “…IntroductionAlthough schizophrenia is a severe mental illness, whose etiology is still largely unknown, its pathogenesis may be associated with dysregulation…”
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    Journal Article
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    Levels of C-reactive protein (CRP) in patients with schizophrenia, unipolar depression and bipolar disorder by Wysoki ski, Adam, Margulska, Aleksandra, Strzelecki, Dominik, K oszewska, Iwona

    Published in Nordic journal of psychiatry (01-07-2015)
    “…Abstract Objective: C-reactive protein (CRP) is the major acute-phase plasma protein. Studies show that patients with various mental disorders have elevated…”
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    Journal Article