Search Results - "Wynne, David J"

Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components by Wynne, David J, Funabiki, Hironori

“…It is widely accepted that the kinetochore is built on CENP-A-marked centromeric chromatin in a hierarchical order from inner to outer kinetochore. Recruitment…”
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Making an effective switch at the kinetochore by phosphorylation and dephosphorylation by Funabiki, Hironori, Wynne, David J

“…The kinetochore, the proteinaceous structure on the mitotic centromere, functions as a mechanical latch that hooks onto microtubules to support directional…”
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Dual recognition of chromatin and microtubules by INCENP is important for mitotic progression by Wheelock, Michael S, Wynne, David J, Tseng, Boo Shan, Funabiki, Hironori

“…The chromosomal passenger complex (CPC), composed of inner centromere protein (INCENP), Survivin, Borealin, and the kinase Aurora B, contributes to the…”
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Heterogeneous architecture of vertebrate kinetochores revealed by three-dimensional superresolution fluorescence microscopy by Wynne, David J, Funabiki, Hironori

“…The kinetochore is often depicted as having a disk-like architecture in which the outer layer of proteins, which engage microtubules and control checkpoint…”
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Cytoskeletal Forces Span the Nuclear Envelope to Coordinate Meiotic Chromosome Pairing and Synapsis by Sato, Aya, Isaac, Berith, Phillips, Carolyn M., Rillo, Regina, Carlton, Peter M., Wynne, David J., Kasad, Roshni A., Dernburg, Abby F.

“…During meiosis, each chromosome must pair with its unique homologous partner, a process that usually culminates with the formation of the synaptonemal complex…”
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Dynein-dependent processive chromosome motions promote homologous pairing in C. elegans meiosis by Wynne, David J, Rog, Ofer, Carlton, Peter M, Dernburg, Abby F

“…Meiotic chromosome segregation requires homologue pairing, synapsis, and crossover recombination, which occur during meiotic prophase. Telomere-led chromosome…”
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ZHP-3 acts at crossovers to couple meiotic recombination with synaptonemal complex disassembly and bivalent formation in C. elegans by Bhalla, Needhi, Wynne, David J, Jantsch, Verena, Dernburg, Abby F

“…Crossover recombination and the formation of chiasmata normally ensure the proper segregation of homologous chromosomes during the first meiotic division…”
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Protein Immunodepletion and Complementation in Xenopus laevis Egg Extracts by Jenness, Christopher, Wynne, David J, Funabiki, Hironori

“…The egg extract system has been widely used to study cell cycle events, including DNA replication, nuclear envelope formation, spindle assembly, chromosome…”
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Genetic analysis of Caenorhabditis elegans Haspin-like genes shows that hasp-1 plays multiple roles in the germline by Macaraeg, Jommel, Reinhard, Isaac, Ward, Matthew, Carmeci, Danielle, Stanaway, Madison, Moore, Amy, Hagmann, Ethan, Brown, Katherine, Wynne, David J.

“…Haspin is a histone kinase that promotes error-free chromosome segregation by recruiting the chromosomal passenger complex (CPC) to mitotic and meiotic…”
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Genetic analysis of C. elegans Haspin-like genes shows that hasp-1 plays multiple roles in the germline by Macaraeg, Jommel, Reinhard, Isaac, Ward, Matthew, Carmeci, Danielle, Stanaway, Madison, Moore, Amy, Hagmann, Ethan, Brown, Katherine, Wynne, David J

“…Haspin is a histone kinase that promotes error-free chromosome segregation by recruiting the Chromosomal Passenger Complex (CPC) to mitotic and meiotic…”
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Vibrio vulnificus iron transport mutant has normal pathogenicity in C. elegans by Bowles, Adria, Wynne, David, Kenton, Ryan

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Correction: ZHP-3 Acts at Crossovers to Couple Meiotic Recombination with Synaptonemal Complex Disassembly and Bivalent Formation in C. elegans by Bhalla, Needhi, Wynne, David J., Jantsch, Verena, Dernburg, Abby F.

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Correction: ZHP-3 Acts at Crossovers to Couple Meiotic Recombination with Synaptonemal Complex Disassembly and Bivalent Formation in by Needhi Bhalla, David J. Wynne, Verena Jantsch, Abby F. Dernburg

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ZHP-3 Acts at Crossovers to Couple Meiotic Recombination with Synaptonemal Complex Disassembly and Bivalent Formation in C. elegans: e1000235 by Bhalla, Needhi, Wynne, David J, Jantsch, Verena, Dernburg, Abby F

“…Crossover recombination and the formation of chiasmata normally ensure the proper segregation of homologous chromosomes during the first meiotic division…”
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The Role and Mechanism of Meiotic Chromosome Motion in C. elegans by Wynne, David J

“…Proper meiotic chromosome segregation in C. elegans requires homolog pairing, synapsis, and recombination. The mechanisms underlying homologous chromosome…”
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