Search Results - "Wynne, Colin"

Evaluation of Microwave-Accelerated Residue-Specific Acid Cleavage for Proteomic Applications by Swatkoski, Stephen, Gutierrez, Peter, Wynne, Colin, Petrov, Alexey, Dinman, Jonathan D, Edwards, Nathan, Fenselau, Catherine

“…Microwave-accelerated proteolysis using acetic acid has been shown to occur specifically on either or both sides of aspartic acid residues. This chemical…”
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Deconvolution and Database Search of Complex Tandem Mass Spectra of Intact Proteins by Liu, Xiaowen, Inbar, Yuval, Dorrestein, Pieter C., Wynne, Colin, Edwards, Nathan, Souda, Puneet, Whitelegge, Julian P., Bafna, Vineet, Pevzner, Pavel A.

“…Top-down proteomics studies intact proteins, enabling new opportunities for analyzing post-translational modifications. Because tandem mass spectra of intact…”
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High-Throughput Middle-Down Analysis Using an Orbitrap by Cannon, Joe, Lohnes, Karen, Wynne, Colin, Wang, Yan, Edwards, Nathan, Fenselau, Catherine

“…This report demonstrates the application of a capillary LC-LTQ-orbitrap system to provide automated middle-down analysis of proteolytic peptides in the mass…”
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Deconvolution and database search of complex tandem mass spectra of intact proteins: a combinatorial approach by Liu, Xiaowen, Inbar, Yuval, Dorrestein, Pieter C, Wynne, Colin, Edwards, Nathan, Souda, Puneet, Whitelegge, Julian P, Bafna, Vineet, Pevzner, Pavel A

“…Top-down proteomics studies intact proteins, enabling new opportunities for analyzing post-translational modifications. Because tandem mass spectra of intact…”
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Phyloproteomic classification of unsequenced organisms by top-down identification of bacterial proteins using capLC-MS/MS on an Orbitrap by Wynne, Colin, Edwards, Nathan J, Fenselau, Catherine

“…Currently, most MS-based proteomic studies of bacteria and archea match experimental data to known amino acid sequences from the target organism. Top-down…”
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Top-Down Identification of Protein Biomarkers in Bacteria with Unsequenced Genomes by Wynne, Colin, Fenselau, Catherine, Demirev, Plamen A, Edwards, Nathan

“…MALDI mass spectrometry-based systems for rapid characterization of microorganisms in biodefense or medical diagnostics usually detect intact proteins in the…”
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Characterization of Drug-Product-Related Impurities and Variants of a Therapeutic Monoclonal Antibody by Higher Energy C‑Trap Dissociation Mass Spectrometry by Wang, Deyun, Wynne, Colin, Gu, Flora, Becker, Chris, Zhao, Jia, Mueller, Hans-Martin, Li, Huijuan, Shameem, Mohammed, Liu, Yan-Hui

“…Mass spectrometry (MS) characterization of recombinant monoclonal antibody (mAb) drugs and their degraded and/or post-translationally modified counterparts,…”
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Phyloproteomic classification of unsequenced organisms by top-down identification of bacterial proteins using capLC-MS/MS on an Orbitrap : Top-down Proteomics by WYNNE, Colin, EDWARDS, Nathan J, FENSELAU, Catherine

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Top-down analysis of bacterial proteins by high-resolution mass spectrometry by Wynne, Colin Michael

“…In the biodefense and medical diagnostic fields, MALDI mass spectrometry-based systems are used for rapid characterization of microorganisms generally by…”
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