Search Results - "Wynn, RF"

CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation by Martin, Emmanuel, Palmic, Noé, Sanquer, Sylvia, Lenoir, Christelle, Hauck, Fabian, Mongellaz, Cédric, Fabrega, Sylvie, Nitschké, Patrick, Esposti, Mauro Degli, Schwartzentruber, Jeremy, Taylor, Naomi, Majewski, Jacek, Jabado, Nada, Wynn, Robert F., Picard, Capucine, Fischer, Alain, Arkwright, Peter D., Latour, Sylvain

“…Loss-of-function mutations in the human CTP synthase 1 gene cause an immunodeficiency disease with impaired T cell proliferation after antigen stimulation,…”
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G542(P) Comparing fertility outcomes in paediatric patients treated with busulfan or treosulfan prior to haematopoietic stem cell transplant by Prathivadi Bhayankaram, N, Fitzgerald, CT, Wynn, RF

“…BackgroundHaematopoietic stem cell transplant (HCT) can be used to treat malignant and non-malignant conditions. Prior to HCT, patients have conditioning with…”
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Alternative donor transplantation for severe aplastic anemia: a comparative study of the SAAWP EBMT by Montoro, Juan, Eikema, Dirk-Jan, Tuffnell, Joe, Potter, Victoria, Kalwak, Krzysztof, Halkes, Constantijn J. M., Kulagin, Alexander, Collin, Matthew, Wynn, Robert F., Robinson, Stephen, Nicholson, Emma, Sengeloev, Henrik, Clay, Jennifer, Halahleh, Khalid, Skorobogatova, Elena, Sanz, Jaime, Passweg, Jakob, Mielke, Stephan, Ryhänen, Samppa, Carpenter, Ben, Gedde-Dahl, Tobias, Tholouli, Eleni, Fanin, Renato, Lewalle, Philippe, Kulasekararaj, Austin, Risitano, Antonio, Peffault de Latour, Régis

“…•SCT from MUD offers superior survival outcomes for severe aplastic anemia compared with both MMUD and Haplo SCT.•The decision between an MMUD and Haplo donor…”
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Graft-Versus-Host Disease after Anti-CD19 Chimeric Antigen Receptor T-Cell Infusion Post Allogeneic Hematopoietic Cell Transplantation: A Transplant Complications and Paediatric Disease Working Parties EBMT Joint Study by Orti, Guillermo, Peczynski, Christophe, Koenecke, Christian, Boreland, William, O'Reilly, Maeve, Bornhäuser, Martin, Balduzzi, Adriana, Besley, Caroline, Kalwak, Krzysztof, Ryhanen, Samppa, Güngör, Tayfun, Wynn, Robert F., Bader, Peter, Mielke, Stephan, Blaise, Didier, Amrolia, Persis, Yakoub-Agha, Ibrahim, Calkoen, Friso G. J., Schubert, Maria-Luisa, Potter, Victoria, Holter, Wolfgang, Kröger, Nicolaus, Kwon, Mi, Sengeloev, Henrik, Schoemans, Helene, Moiseev, Ivan Sergeevich, Penack, Olaf, Peric, Zinaida

“…Background Anti-CD19 chimeric antigen receptor T-cells (CART) have been incorporated into the therapeutic landscape of B-acute lymphoblastic leukemia (B-ALL)…”
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Study of Telomere Length Reveals Rapid Aging of Human Marrow Stromal Cells following In Vitro Expansion by Baxter, Melissa A., Wynn, Robert F., Jowitt, Simon N., Wraith, J. Ed, Fairbairn, Leslie J., Bellantuono, Ilaria

“…Human marrow stromal cells (MSCs) can be isolated from bone marrow and differentiate into multiple tissues in vitro and in vivo. These properties make them…”
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A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow by Wynn, Robert F., Hart, Claire A., Corradi-Perini, Carla, O'Neill, Liam, Evans, Caroline A., Wraith, J. Ed, Fairbairn, Leslie J., Bellantuono, Ilaria

“…Homing of bone marrow stromal cells (MSCs) to bone and bone marrow after transplantation, important for the correction of conditions such as metabolic storage…”
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Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation for Congenital Amegakaryocytic Thrombocytopenia, a PDWP/EBMT Study by Aldebert, Clemence, Fahd, Mony, Galimard, Jacques-Emmanuel, Ghemlas, Ibrahim A., Zecca, Marco, Silva, Juliana, Mohseny, Alexander, Kupesiz, Alphan, Hamladji, Rose-Marie, Miranda, Nuno, Gungor, Tayfun, Wynn, Robert F, Merli, Pietro, Sundin, Mikael, Faraci, Maura, Díaz-de-Heredia, Cristina, Burkhardt, Birgit, Bordon, Victoria, Jubert, Charlotte, Bader, Peter, Ifversen, Marianne, Herrera Arroyo, Concepcion, Maximova, Natalia, Riesco, Susana, Stein, Jerry, Dalissier, Arnaud, Locatelli, Franco, Kalwak, Krzysztof, Dalle, Jean-Hugues, Corbacioglu, Selim

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Adenovirus infections after allogeneic hematopoietic cell transplantation in children and adults: a study from the Infectious Diseases Working Party of the European Society for Blood and Marrow Transplantation by Styczynski, Jan, Tridello, Gloria, Knelange, Nina, Wendel, Lotus, Ljungman, Per, Mikulska, Malgorzata, Gil, Lidia, Cesaro, Simone, Averbuch, Diana, von dem Borne, Peter, Xhaard, Aliénor, Mielke, Stephan, Neven, Benedicte, Snowden, John A., Dalle, Jean-Hugues, Rubio, Marie Thérèse, Crawley, Charles, Maertens, Johan, Kuball, Jurgen, Chevallier, Patrice, Michel, Gérard, Gabriel, Melissa, Burns, David, Wynn, Robert F., Renard, Cecile, Blijlevens, Nicole, Jubert, Charlotte, Gedde-Dahl, Tobias, Collin, Matthew, Labussiere-Wallet, Helene, Kalwak, Krzysztof, Broers, Annoek E. C., Yakoub-Agha, Ibrahim, Itäla-Remes, Maija, de la Camara, Rafael

“…The objective of the study was the analysis of clinical types, outcomes, and risk factors associated with the outcome of adenovirus (ADV) infection, in…”
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G408(P) Cytokine storm associated multi-organ failure with poor neurological outcome, during rituximab administration in a child with relapsed acute lymphoblastic leukaemia and ebv related lymphoproliferative disease by Kanaris, C, Wynn, RF, Konstantinidis, A

“…We present the case of a 6 year old boy, with relapsed Acute Lymphoblastic Leukaemia and subsequent matched unrelated bone marrow transplant. His Epstein Barr…”
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Failure of allogeneic bone marrow transplantation to correct Diamond-Blackfan anaemia despite haemopoietic stem cell engraftment by WYNN, R. F, GRAINGER, J. D, CARR, T. F, EDEN, O. B, STEVENS, R. F, WILL, A. M

“…We report the case of a 10-year-old boy with congenital pure red cell aplasia (Diamond-Blackfan anaemia) who received an allogeneic bone marrow transplant…”
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Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation by Bognàr, Tim, Bartelink, Imke H., Egberts, Toine C.G., Rademaker, Carin M.A., Versluys, A. Birgitta, Slatter, Mary A., Kletzel, Morris, Nath, Christa E., Cuvelier, Geoffrey D.E, Savic, Rada M., Dvorak, Christopher, Long-Boyle, Janel R., Cowan, Morton J., Bittencourt, Henrique, Bredius, Robbert G.M., Güngör, Tayfun, Shaw, Peter J., Ansari, Marc, Hassan, Moustapha, Krajinovic, Maja, Hempel, Georg, Marktel, Sarah, Chiesa, Robert, Théoret, Yves, Lund, Troy, Orchard, Paul J., Wynn, Robert F., Boelens, Jaap Jan, Lalmohamed, Arief

“…Intravenous busulfan is widely used as part of myeloablative conditioning regimens in children and young adults undergoing allogeneic hematopoietic cell…”
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Paroxysmal cold haemoglobinuria of childhood: a review of the management and unusual presenting features of six cases by Wynn, R. F., Stevens, R. F., Bolton-Maggs, P. H. B., Schwe, K., Will, A. M.

“…We report six cases of children presenting with paroxysmal cold haemoglobinuria occurring in a 3‐year period in the north‐west of England. In all six cases the…”
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Targeted busulfan-based reduced-intensity conditioning and HLA-matched HSCT cure hemophagocytic lymphohistiocytosis by Felber, Matthias, Steward, Colin G., Kentouche, Karim, Fasth, Anders, Wynn, Robert F., Zeilhofer, Ulrike, Haunerdinger, Veronika, Volkmer, Benjamin, Prader, Seraina, Gruhn, Bernd, Ehl, Stephan, Lehmberg, Kai, Müller, Daniel, Gennery, Andrew R., Albert, Michael H., Hauck, Fabian, Rao, Kanchan, Veys, Paul, Hassan, Moustapha, Lankester, Arjan C., Schmid, Jana Pachlopnik, Hauri-Hohl, Mathias M., Güngör, Tayfun

“…Reduced-intensity/reduced-toxicity conditioning and allogeneic T-cell replete hematopoietic stem cell transplantation are curative in patients with…”
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Allogeneic hematopoietic stem cell transplantation in leukocyte adhesion deficiency type I and III by Bakhtiar, Shahrzad, Salzmann-Manrique, Emilia, Blok, Henric-Jan, Eikema, Dirk-Jan, Hazelaar, Sheree, Ayas, Mouhab, Toren, Amos, Goldstein, Gal, Moshous, Despina, Locatelli, Franco, Merli, Pietro, Michel, Gerard, Öztürk, Gülyüz, Schulz, Ansgar, Heilmann, Carsten, Ifversen, Marianne, Wynn, Rob F., Aleinikova, Olga, Bertrand, Yves, Tbakhi, Abdelghani, Veys, Paul, Karakukcu, Musa, Kupesiz, Alphan, Ghavamzadeh, Ardeshir, Handgretinger, Rupert, Unal, Emel, Perez-Martinez, Antonio, Gokce, Muge, Porta, Fulvio, Aksu, Tekin, Karasu, Gülsün, Badell, Isabel, Ljungman, Per, Skorobogatova, Elena, Yesilipek, Akif, Zuckerman, Tsila, Bredius, Robbert R.G., Stepensky, Polina, Shadur, Bella, Slatter, Mary, Gennery, Andrew R., Albert, Michael H., Bader, Peter, Lankester, Arjan

“…Type I and III leukocyte adhesion deficiencies (LADs) are primary immunodeficiency disorders resulting in early death due to infections and additional bleeding…”
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Case report of dapsone-related thrombocytosis in an AIDS patient by Wynn, R F, Laing, R B, Leen, C L

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Treatment of Epstein-Barr-virus-associated primary CNS B cell lymphoma with allogeneic T-cell immunotherapy and stem-cell transplantation by Wynn, Robert F, Arkwright, Peter D, Haque, Tanzina, Gharib, Maged I, Wilkie, Gwen, Morton-Jones, Marie, Crawford, Dorothy H

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Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants by Wynn, Robert F, Cross, Michael A, Hatton, Claire, Will, Andrew M, Lashford, Linda S, Dexter, T Michael, Testa, Nydia G

“…The establishment of donor-derived haemopoiesis in the recipients of allogeneic bone-marrow transplants (BMT) involves extensive proliferation of haemopoietic…”
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Dynamics of telomere shortening in neutrophils and T lymphocytes during ageing and the relationship to skewed X chromosome inactivation patterns by Robertson, Jane D., Gale, Rosemary E., Wynn, Robert F., Dougal, Mark, Linch, David C., Testa, Nydia G., Chopra, Rajesh

“…Human haemopoiesis undergoes profound changes throughout life, resulting in compromised regenerative capacity of haemopoietic stem cells. It has been suggested…”
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The impact of monitoring Epstein-Barr virus PCR in paediatric bone marrow transplant patients: Can it successfully predict outcome and guide intervention? by Greenfield, Hayley M., Gharib, Maged I., Turner, Andrew J.L., Guiver, Malcolm, Carr, Trevor, Will, Andrew M., Wynn, Robert F.

“…Background Epstein–Barr virus (EBV) associated lymphoproliferative disease is a complication of haemopoietic stem cell transplantation (HSCT). In certain…”
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Abnormal telomere shortening in leucocytes of children with Shwachman–Diamond syndrome by Thornley, Ian, Dror, Yigal, Sung, Lilian, Wynn, Rob F., Freedman, Melvin H.

“…Haemopoietic dysfunction, ranging from single‐lineage cytopenia to severe aplasia and/or myelodysplasia (MDS), is prominent in Shwachman–Diamond syndrome…”
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