Search Results - "Wynick, D."

S.20.02 The neurotrophic effects of galanin by Wynick, D

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Feeding Behaviour in Galanin Knockout Mice Supports a Role of Galanin in Fat Intake and Preference by Adams, A. C., Clapham, J. C., Wynick, D., Speakman, J. R.

“…It has been widely suggested that saturated fat consumption has fuelled the current obesity epidemic. Macronutrient choices appear to be important not only as…”
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Galanin acts as a trophic factor to the central and peripheral nervous systems by Hobson, S-A, Bacon, A, Elliot-Hunt, C R, Holmes, F E, Kerr, N C H, Pope, R, Vanderplank, P, Wynick, D

“…The neuropeptide galanin is widely, but not ubiquitously, expressed in the adult nervous system. Its expression is markedly upregulated in many neuronal…”
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Novel mRNA isoforms of the sodium channels Na(v)1.2, Na(v)1.3 and Na(v)1.7 encode predicted two-domain, truncated proteins by Kerr, N C H, Holmes, F E, Wynick, D

“…The expression of voltage-gated sodium channels is regulated at multiple levels, and in this study we addressed the potential for alternative splicing of the…”
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Targeted disruption of galanin: new insights from knock-out studies by Wynick, D., Bacon, A.

“…The neuropeptide galanin has a widespread but no means ubiquitous expression pattern in the nervous and endocrine systems. Profound changes in the levels and…”
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NOVEL mRNA ISOFORMS OF THE SODIUM CHANNELS Nav1.2, Nav1.3 AND Nav1.7 ENCODE PREDICTED TWO-DOMAIN, TRUNCATED PROTEINS by KERR, N. C. H, HOLMES, F. E, WYNICK, D

“…The expression of voltage-gated sodium channels is regulated at multiple levels, and in this study we addressed the potential for alternative splicing of the…”
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Use of genetically engineered transgenic mice to investigate the role of galanin in the peripheral nervous system after injury by Holmes, F.E., Mahoney, S-A., Wynick, D.

“…The neuropeptide galanin is present at high levels within the dorsal root ganglia (DRG) and spinal cord during development and after peripheral nerve damage in…”
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Galanin Regulates Prolactin Release and Lactotroph Proliferation by Wynick, David, Small, Caroline J., Bacon, Andrea, Holmes, Fiona E., Norman, Michael, Ormandy, Christopher J., Kilic, Eser, Niall C. H. Kerr, Ghatei, Mohammad, Talamantes, Frank, Bloom, Stephen R., Pachnis, Vassilis

“…The neuropeptide galanin is predominantly expressed by the lactotrophs (the prolactin secreting cell type) in the rodent anterior pituitary and in the median…”
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Obesity and Endocrine Dysfunction in Mice with Deletions of both Neuropeptide Y and Galanin by Hohmann, J. G., Teklemichael, D. N., Weinshenker, D., Wynick, D., Clifton, D. K., Steiner, R. A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The role of galanin as a multi-functional neuropeptide in the nervous system by Wynick, David, Thompson, Stephen WN, McMahon, Stephen B

“…The neuropeptide galanin is expressed developmentally in the DRG and is rapidly up-regulated 120-fold after peripheral nerve section in the adult. The…”
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Microdialysis in freely moving mice: determination of acetylcholine, serotonin and noradrenaline release in galanin transgenic mice by Kehr, J, Yoshitake, T, Wang, F.H, Wynick, D, Holmberg, K, Lendahl, U, Bartfai, T, Yamaguchi, M, Hökfelt, T, Ögren, S.O

“…In the present study, we describe micro-surgical methods for simultaneous implantation of a microdialysis probe and an intraventricular injection cannula via…”
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Galanin-like peptide (GALP) is expressed in rat hypothalamus and pituitary, but not in DRG by Kerr, Niall C. H, Holmes, Fiona E, Wynick, David

“…Galanin-like peptide (GALP) was recently purified on the basis of its preferential activation of galanin receptor subtype 2 (GALR2) compared with galanin…”
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Galanin – 25 years with a multitalented neuropeptide: Galanin acts as a trophic factor to the central and peripheral nervous systems by Hobson, S.-A., Bacon, A., Elliot-Hunt, C. R., Holmes, F. E., Kerr, N. C. H., Pope, R., Vanderplank, P., Wynick, D.

“… The neuropeptide galanin is widely, but not ubiquitously, expressed in the adult nervous system. Its expression is markedly upregulated in many neuronal…”
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Targeted Disruption of the Murine Galanin Gene by WYNICK, DAVID, SMALL, CAROLINE J., BLOOM, STEPHEN R., PACHNIS, VASSILIS

“…: The 29 amino acid neuropeptide galanin is widely distributed in the nervous and endocrine systems; highest levels of galanin synthesis and storage occur…”
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S.20.05 Galanin and Alzheimer's disease by Mufson, E.J, Counts, S.E, Ginsberg, S.D, Perez, S.E, Elliott-Hunt, C, Wynick, D

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Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity by Lang, Roland, Gundlach, Andrew L, Holmes, Fiona E, Hobson, Sally A, Wynick, David, Hökfelt, Tomas, Kofler, Barbara

“…Galanin was first identified 30 years ago as a "classic neuropeptide," with actions primarily as a modulator of neurotransmission in the brain and peripheral…”
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Galanin regulates spatial memory but not visual recognition memory or synaptic plasticity in perirhinal cortex by Massey, P.V, Warburton, E.C, Wynick, D, Brown, M.W, Bashir, Z.I

“…It has previously been shown that the neuropeptide galanin plays a role in the age-dependent regulation of hippocampal synaptic plasticity and spatial memory…”
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Characterization of a High-Affinity Galanin Receptor in the Rat Anterior Pituitary: Absence of Biological Effect and Reduced Membrane Binding of the Antagonist M15 Differentiate it From the Brain/Gut Receptor by Wynick, David, Smith, David M., Ghatei, Mohammad, Akinsanya, Karen, Bhogal, Ranjev, Purkiss, Paul, Byfield, Peter, Yanaihara, Noboru, Bloom, Stephen R.

“…Structure-activity studies demonstrate that galanin fragments 1-15 and 2-29 are fully active, whereas fragment 3-29 has been reported to be inactive, in a…”
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Signalling pathways mediating secretory and mitogenic responses to galanin and pituitary adenylate cyclase-activating polypeptide in the 235-1 clonal rat lactotroph cell line by Hammond, P J, Smith, D M, Akinsanya, K O, Mufti, W A, Wynick, D, Bloom, S R

“…The neuropeptides galanin and pituitary adenylate cyclase-activating peptide (PACAP) have been implicated in the physiological regulation of lactotroph…”
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Novel mRNA isoforms of the sodium channels Na sub(v)1.2, Na sub(v)1.3 and Na sub(v)1.7 encode predicted two-domain, truncated proteins by Kerr, NCH, Holmes, F E, Wynick, D

“…The expression of voltage-gated sodium channels is regulated at multiple levels, and in this study we addressed the potential for alternative splicing of the…”
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