Search Results - "Wyneken, Úrsula"

Astrocyte-derived extracellular vesicles in stress-associated mood disorders. Does the immune system get astrocytic? by Luarte, Alejandro, Nardocci, Gino, Chakraborty, Ankush, Batiz, Luis Federico, Pino-Lagos, Karina, Wyneken, Úrsula

“…Life stressors can wreak havoc on our health, contributing to mood disorders like major depressive disorder (MDD), a widespread and debilitating condition…”
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Methadone directly impairs central nervous system cells in vitro by De Gregorio, Cristian, Gallardo, Javiera, Berríos-Cárcamo, Pablo, Handy, Álex, Santapau, Daniela, González-Madrid, Antonia, Ezquer, Marcelo, Morales, Paola, Luarte, Alejandro, Corvalán, Daniela, Wyneken, Úrsula, Ezquer, Fernando

“…Methadone is a synthetic long-acting opioid that is increasingly used in the replacement therapy of opioid-addicted patients, including pregnant women…”
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Maternal stress during pregnancy alters circulating small extracellular vesicles and enhances their targeting to the placenta and fetus by Sánchez-Rubio, Mario, Abarzúa-Catalán, Lorena, Del Valle, Ana, Méndez-Ruette, Maxs, Salazar, Natalia, Sigala, Jacinta, Sandoval, Soledad, Godoy, María Inés, Luarte, Alejandro, Monteiro, Lara J, Romero, Roberto, Choolani, Mahesh A, Wyneken, Úrsula, Illanes, Sebastián E, Bátiz, Luis Federico

“…Maternal psychological distress during pregnancy can negatively impact fetal development, resulting in long-lasting consequences for the offspring. These…”
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Neuropilin‐1 is present on Foxp3+ T regulatory cell‐derived small extracellular vesicles and mediates immunity against skin transplantation by Campos‐Mora, Mauricio, De Solminihac, Javiera, Rojas, Carolina, Padilla, Cristina, Kurte, Mónica, Pacheco, Rodrigo, Kaehne, Thilo, Wyneken, Úrsula, Pino‐Lagos, Karina

“…Among the mechanisms of suppression that T regulatory (Treg) cells exert to control the immune responses, the secretion of small extracellular vesicles (sEV)…”
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Editorial: Medicinal drugs, the effect on memories and beyond by Moreira-Rodrigues, Mónica, Ampuero, Estibaliz, Wyneken, Ursula

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Potential Therapies by Stem Cell-Derived Exosomes in CNS Diseases: Focusing on the Neurogenic Niche by Lafourcade, Carlos, Wyneken, Ursula, Bátiz, Luis Federico, Luarte, Alejandro

“…Neurodegenerative disorders are one of the leading causes of death and disability and one of the biggest burdens on health care systems. Novel approaches using…”
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Bulk serum extracellular vesicles from stressed mice show a distinct proteome and induce behavioral and molecular changes in naive mice by Monteleone, Melisa C, Billi, Silvia C, Abarzúa-Catalán, Lorena, Henzi, Roberto, Fernández, Eliana M, Kaehne, Thilo, Wyneken, Ursula, Brocco, Marcela A

“…Chronic stress can trigger several pathologies including mood disorders for which no clear diagnostic molecular markers have been established yet. Attractive…”
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eNOS-dependent S-nitrosylation of the NF-κB subunit p65 has neuroprotective effects by Caviedes, Ariel, Maturana, Barbara, Corvalán, Katherina, Engler, Alexander, Gordillo, Felipe, Varas-Godoy, Manuel, Smalla, Karl-Heinz, Batiz, Luis Federico, Lafourcade, Carlos, Kaehne, Thilo, Wyneken, Ursula

“…Cell death by glutamate excitotoxicity, mediated by N -methyl- d -aspartate (NMDA) receptors, negatively impacts brain function, including but not limited to…”
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Astrocytes at the Hub of the Stress Response: Potential Modulation of Neurogenesis by miRNAs in Astrocyte- Derived Exosomes by Henzi, Roberto, Lafourcade, Carlos, Bátiz, Luis Federico, Caviedes, Ariel, Cisternas, Pablo, Luarte, Alejandro, Wyneken, Ursula

“…Repetitive stress negatively affects several brain functions and neuronal networks. Moreover, adult neurogenesis is consistently impaired in chronic stress…”
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Maternal exposure to a high-magnitude earthquake during pregnancy influences pre-reading skills in early childhood by Bátiz, Luis Federico, Palmeiro-Silva, Yasna K., Rice, Gregory E., Monteiro, Lara J., Galaburda, Albert M., Romero, Roberto, Choolani, Mahesh A., Wyneken, Ursula, Orellana, Pelusa, Illanes, Sebastián E.

“…Exposure to an adverse prenatal environment can influence fetal development and result in long-lasting changes in the offspring. However, the association…”
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The multifaceted effects of fluoxetine treatment on cognitive functions by Ampuero, Estíbaliz, Luarte, Alejandro, Flores, Francisca Sofia, Soto, Antonia Ignacia, Pino, Catalina, Silva, Viviana, Erlandsen, Macarena, Concha, Teresita, Wyneken, Ursula

“…Fluoxetine, the prototypical selective serotonin reuptake inhibitor (SSRI), is widely used to treat major depressive disorder (MDD) and a variety of other…”
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Neuronal activity-dependent ATP enhances the pro-growth effect of repair Schwann cell extracellular vesicles by increasing their miRNA-21 loading by Saquel, Cristian, Catalan, Romina J., Lopez-Leal, Rodrigo, Ramirez, Ramon A., Necuñir, David, Wyneken, Ursula, Lamaze, Christophe, Court, Felipe A.

“…Functional recovery after peripheral nerve injuries is critically dependent on axonal regeneration. Several autonomous and non-cell autonomous processes…”
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Astrocyte-Derived Small Extracellular Vesicles Regulate Dendritic Complexity through miR-26a-5p Activity by Luarte, Alejandro, Henzi, Roberto, Fernández, Anllely, Gaete, Diego, Cisternas, Pablo, Pizarro, Matias, Batiz, Luis Federico, Villalobos, Isabel, Masalleras, Matias, Vergara, Rodrigo, Varas-Godoy, Manuel, Abarzua-Catalan, Lorena, Herrera-Molina, Rodrigo, Lafourcade, Carlos, Wyneken, Ursula

“…In the last few decades, it has been established that astrocytes play key roles in the regulation of neuronal morphology. However, the contribution of…”
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Caffeic Acid Phenethyl Ester (CAPE): Biosynthesis, Derivatives and Formulations with Neuroprotective Activities by Pérez, Rebeca, Burgos, Viviana, Marín, Víctor, Camins, Antoni, Olloquequi, Jordi, González-Chavarría, Iván, Ulrich, Henning, Wyneken, Ursula, Luarte, Alejandro, Ortiz, Leandro, Paz, Cristian

“…Neurodegenerative disorders are characterized by a progressive process of degeneration and neuronal death, where oxidative stress and neuroinflammation are key…”
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Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG by Espinoza, Sofía, Arredondo, Sebastián B, Barake, Francisca, Carvajal, Francisco, Guerrero, Fernanda G, Segovia-Miranda, Fabian, Valenzuela, David M, Wyneken, Ursula, Rojas-Fernández, Alejandro, Cerpa, Waldo, Massardo, Loreto, Varela-Nallar, Lorena, González, Alfonso

“…Cognitive dysfunction (CD) is common among patients with the autoimmune disease systemic lupus erythematosus (SLE). Anti-ribosomal P autoantibodies associate…”
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Behavioral and Molecular Responses to Exogenous Cannabinoids During Pentylenetetrazol-Induced Convulsions in Male and Female Rats by Zirotti Rosenberg, Antonella, Méndez-Ruette, Maxs, Gorziglia, Mario, Alzerreca, Benjamín, Cabello, Javiera, Kaufmann, Sofía, Rambousek, Lukas, Iturriaga Jofré, Andrés, Wyneken, Ursula, Lafourcade, Carlos A.

“…Epilepsy is a disabling, chronic brain disease,affecting ~1% of the World’s population, characterized by recurrent seizures (sudden, uncontrolled brain…”
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Two Chronic Stress Models Based on Movement Restriction in Rats Respond Selectively to Antidepressant Drugs: Aldolase C As a Potential Biomarker by Ampuero, Estibaliz, Luarte, Alejandro, Santibañez, Marcos, Varas-Godoy, Manuel, Toledo, Jorge, Diaz-Veliz, Gabriela, Cavada, Gabriel, Rubio, F. Javier, Wyneken, Ursula

“…Background: Clinically depressed individuals respond to different types of antidepressants, suggesting that different neurobiological mechanisms may be…”
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Semipermeable Cellulose Beads Allow Selective and Continuous Release of Small Extracellular Vesicles (sEV) From Encapsulated Cells by Zavala, Gabriela, Ramos, María-Paz, Figueroa-Valdés, Aliosha I., Cisternas, Pablo, Wyneken, Ursula, Hernández, Macarena, Toa, Pauline, Salmons, Brian, Dangerfield, John, Gunzburg, Walter H., Khoury, Maroun

“…The clinical benefit of therapies using Mesenchymal Stem Cells (MSCs) is attributable to their pleiotropic effect over cells and tissues, mainly through their…”
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Endothelial Nitric Oxide Synthase Is Present in Dendritic Spines of Neurons in Primary Cultures by Caviedes, Ariel, Varas-Godoy, Manuel, Lafourcade, Carlos, Sandoval, Soledad, Bravo-Alegria, Javiera, Kaehne, Thilo, Massmann, Angela, Figueroa, Jorge P, Nualart, Francisco, Wyneken, Ursula

“…Nitric oxide exerts important regulatory functions in various brain processes. Its synthesis in neurons has been most commonly ascribed to the neuronal nitric…”
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Chronic Fluoxetine Treatment Induces Maturation-Compatible Changes in the Dendritic Arbor and in Synaptic Responses in the Auditory Cortex by Ampuero, Estibaliz, Cerda, Mauricio, Härtel, Steffen, Rubio, Francisco Javier, Massa, Solange, Cubillos, Paula, Abarzúa-Catalán, Lorena, Sandoval, Rodrigo, Galaburda, Albert M, Wyneken, Ursula

“…Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) used to treat mood and anxiety disorders. Chronic treatment with this antidepressant drug is…”
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