Search Results - "Wylot, Marta"

Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival by Kettle, Jason G, Alwan, Husam, Bista, Michal, Breed, Jason, Davies, Nichola L, Eckersley, Kay, Fillery, Shaun, Foote, Kevin M, Goodwin, Louise, Jones, David R, Käck, Helena, Lau, Alan, Nissink, J. Willem M, Read, Jon, Scott, James S, Taylor, Ben, Walker, Graeme, Wissler, Lisa, Wylot, Marta

“…Recent literature has claimed that inhibition of the enzyme MTH1 can eradicate cancer. MTH1 is one of the “housekeeping” enzymes that are responsible for…”
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Multiarm, non-randomised, single-centre feasibility study-investigation of the differential biology between benign and malignant renal masses using advanced magnetic resonance imaging techniques (IBM-Renal): protocol by Horvat-Menih, Ines, McLean, Mary A, Zamora-Morales, Maria Jesus, Wylot, Marta, Kaggie, Joshua, Khan, Alixander S, Gill, Andrew B, Duarte, Joao, Locke, Matthew J, Mendichovszky, Iosif, Li, Hao, Priest, Andrew N, Warren, Anne Y, Welsh, Sarah J, Jones, James O, Armitage, James N, Mitchell, Thomas J, Stewart, Grant D, Gallagher, Ferdia A

“…Localised renal masses are an increasing burden on healthcare due to the rising number of cases. However, conventional imaging cannot reliably distinguish…”
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A thermostable, closed SARS-CoV-2 spike protein trimer by Xiong, Xiaoli, Qu, Kun, Ciazynska, Katarzyna A., Hosmillo, Myra, Carter, Andrew P., Ebrahimi, Soraya, Ke, Zunlong, Scheres, Sjors H. W., Bergamaschi, Laura, Grice, Guinevere L., Zhang, Ying, Nathan, James A., Baker, Stephen, James, Leo C., Baxendale, Helen E., Goodfellow, Ian, Doffinger, Rainer, Briggs, John A. G.

“…The spike (S) protein of SARS-CoV-2 mediates receptor binding and cell entry and is the dominant target of the immune system. It exhibits substantial…”
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Discovery of Pyrazolo[1,5‑a]pyrimidine B‑Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors by McCoull, William, Abrams, Roman D, Anderson, Erica, Blades, Kevin, Barton, Peter, Box, Matthew, Burgess, Jonathan, Byth, Kate, Cao, Qing, Chuaqui, Claudio, Carbajo, Rodrigo J, Cheung, Tony, Code, Erin, Ferguson, Andrew D, Fillery, Shaun, Fuller, Nathan O, Gangl, Eric, Gao, Ning, Grist, Matthew, Hargreaves, David, Howard, Martin R, Hu, Jun, Kemmitt, Paul D, Nelson, Jennifer E, O’Connell, Nichole, Prince, D. Bryan, Raubo, Piotr, Rawlins, Philip B, Robb, Graeme R, Shi, Junjie, Waring, Michael J, Whittaker, David, Wylot, Marta, Zhu, Xiahui

“…Inhibition of the protein–protein interaction between B-cell lymphoma 6 (BCL6) and corepressors has been implicated as a therapeutic target in diffuse large…”
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Potent and Selective Inhibitors of the Epidermal Growth Factor Receptor to Overcome C797S-Mediated Resistance by Finlay, M. Raymond V, Barton, Peter, Bickerton, Sue, Bista, Michal, Colclough, Nicola, Cross, Darren A. E, Evans, Laura, Floc’h, Nicolas, Gregson, Clare, Guérot, Carine M, Hargreaves, David, Kang, Xiaoming, Lenz, Eva M, Li, Xu, Liu, Yi, Lorthioir, Olivier, Martin, Matthew J, McKerrecher, Darren, McWhirter, Claire, O’Neill, Daniel, Orme, Jonathan P, Mosallanejad, Arash, Rahi, Amar, Smith, Paul D, Talbot, Verity, Ward, Richard A, Wrigley, Gail, Wylot, Marta, Xue, Lin, Yao, Tieguang, Ye, Yang, Zhao, Xiliang

“…The epidermal growth factor receptor (EGFR) harboring activating mutations is a clinically validated target in non-small-cell lung cancer, and a number of…”
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Monitoring apoptosis in intact cells by high‐resolution magic angle spinning 1H NMR spectroscopy by Wylot, Marta, Whittaker, David T.E., Wren, Stephen A.C., Bothwell, John H., Hughes, Leslie, Griffin, Julian L.

“…Apoptosis maintains an equilibrium between cell proliferation and cell death. Many diseases, including cancer, develop because of defects in apoptosis. A known…”
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Monitoring apoptosis in intact cells by high-resolution magic angle spinning 1 H NMR spectroscopy by Wylot, Marta, Whittaker, David T E, Wren, Stephen A C, Bothwell, John H, Hughes, Leslie, Griffin, Julian L

“…Apoptosis maintains an equilibrium between cell proliferation and cell death. Many diseases, including cancer, develop because of defects in apoptosis. A known…”
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Correction to Discovery of Pyrazolo[1,5‑a]pyrimidine B‑Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors by McCoull, William, Abrams, Roman D, Anderson, Erica, Blades, Kevin, Barton, Peter, Box, Matthew, Burgess, Jonathan, Byth, Kate, Cao, Qing, Chuaqui, Claudio, Carbajo, Rodrigo J, Cheung, Tony, Code, Erin, Ferguson, Andrew D, Fillery, Shaun, Fuller, Nathan O, Gangl, Eric, Gao, Ning, Grist, Matthew, Hargreaves, David, Howard, Martin R, Hu, Jun, Kemmitt, Paul D, Nelson, Jennifer E, O’Connell, Nichole, Prince, D. Bryan, Raubo, Piotr, Rawlins, Philip B, Robb, Graeme R, Shi, Junjie, Waring, Michael J, Whittaker, David, Wylot, Marta, Zhu, Xiahui

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