Search Results - "Wylie, Todd N."

Enhanced virome sequencing using targeted sequence capture by Wylie, Todd N, Wylie, Kristine M, Herter, Brandi N, Storch, Gregory A

“…Metagenomic shotgun sequencing (MSS) is an important tool for characterizing viral populations. It is culture independent, requires no a priori knowledge of…”
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Development and Evaluation of an Enterovirus D68 Real-Time Reverse Transcriptase PCR Assay by Wylie, Todd N, Wylie, Kristine M, Buller, Richard S, Cannella, Maria, Storch, Gregory A

“…We have developed and evaluated a real-time reverse transcriptase PCR (RT-PCR) assay for the detection of human enterovirus D68 (EV-D68) in clinical specimens…”
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The transcriptional profile of coronary arteritis in Kawasaki disease by Rowley, Anne H, Wylie, Kristine M, Kim, Kwang-Youn A, Pink, Adam J, Yang, Amy, Reindel, Rebecca, Baker, Susan C, Shulman, Stanford T, Orenstein, Jan M, Lingen, Mark W, Weinstock, George M, Wylie, Todd N

“…Kawasaki Disease (KD) can cause potentially life-threatening coronary arteritis in young children, and has a likely infectious etiology. Transcriptome…”
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ViroMatch: A Computational Pipeline for the Detection of Viral Sequences from Complex Metagenomic Data by Wylie, Todd N, Wylie, Kristine M

“…ViroMatch is an automated pipeline that takes metagenomic sequencing reads as input and performs iterative nucleotide and translated nucleotide mapping to…”
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Simplified methods for variance estimation in microbiome abundance count data analysis by Shi, Yiming, Liu, Lili, Chen, Jun, Wylie, Kristine M., Wylie, Todd N., Stout, Molly J., Wang, Chan, Zhang, Haixiang, Shih, Ya-Chen T., Xu, Xiaoyi, Zhang, Ai, Park, Sung Hee, Jiang, Hongmei, Liu, Lei

“…The complex nature of microbiome data has made the differential abundance analysis challenging. Microbiome abundance counts are often skewed to the right and…”
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Genome sequence of enterovirus D68 from St. Louis, Missouri, USA by Wylie, Kristine M, Wylie, Todd N, Orvedahl, Anthony, Buller, Richard S, Herter, Brandi N, Magrini, Vincent, Wilson, Richard K, Storch, Gregory A

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Comparison of Metagenomic Sequencing and the NanoString nCounter Analysis System for the Characterization of Bacterial and Viral Communities in Vaginal Samples by Wylie, Todd N, Schrimpf, Jane, Gula, Haley, Herter, Brandi N, Wylie, Kristine M

“…DNA sequencing assays have been used to characterize the vaginal microbiome and to identify associations with clinical outcomes. The purpose of this study was…”
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Whole-Genome Sequencing of Klebsiella pneumoniae Isolates to Track Strain Progression in a Single Patient With Recurrent Urinary Tract Infection by Wylie, Kristine M, Wylie, Todd N, Minx, Patrick J, Rosen, David A

“…is an important uropathogen that increasingly harbors broad-spectrum antibiotic resistance determinants. Evidence suggests that some same-strain recurrences in…”
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Enterovirus D68-associated acute respiratory distress syndrome in adult, United States, 2014 by Farrell, John J, Ikladios, Ossama, Wylie, Kristine M, O'Rourke, Lindsay M, Lowery, Kristin S, Cromwell, Jenna S, Wylie, Todd N, Melendez, Elsa L Vazquez, Makhoul, Yves, Sampath, Rangarajan, Bonomo, Robert A, Storch, Gregory A

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Longitudinal Dynamics of Skin Bacterial Communities in the Context of Staphylococcus aureus Decolonization by Fritz, Stephanie A, Wylie, Todd N, Gula, Haley, Hogan, Patrick G, Boyle, Mary G, Muenks, Carol E, Sullivan, Melanie L, Burnham, Carey-Ann D, Wylie, Kristine M

“…Decolonization with topical antimicrobials is frequently prescribed in health care and community settings to prevent Staphylococcus aureus infection. However,…”
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Virome Analysis and Association of Positive Coxsackievirus B Serology during Pregnancy with Congenital Heart Disease by Garand, Mathieu, Huang, Susie S Y, Goessling, Lisa S, Wan, Fei, Santillan, Donna A, Santillan, Mark K, Brar, Anoop, Wylie, Todd N, Wylie, Kristine M, Eghtesady, Pirooz

“…We have previously shown coxsackievirus B (CVB) to be a potent inducer of congenital heart disease (CHD) in mice. The clinical relevance of these findings in…”
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A Case of Persistent Human Pegivirus Infection in Two Separate Pregnancies of a Woman by Garand, Mathieu, Huang, Susie S Y, Goessling, Lisa S, Santillan, Donna A, Santillan, Mark K, Brar, Anoop, Wylie, Todd N, Wylie, Kristine M, Eghtesady, Pirooz

“…Human pegivirus (HPgV) is best known for persistent, presumably non-pathogenic, infection and a propensity to co-infect with human immunodeficiency virus or…”
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The Post-transplant Lymphoproliferative Disorders-Metagenomic Shotgun Microbial Sequencing (PTLD-MSMS) Study Methods and Protocol by Dharnidharka, Vikas R, Wylie, Kristine M, Wylie, Todd N, Ruzinova, Marianna B, Goss, Charles W, Storch, Gregory A, Mehta-Shah, Neha, Byers, Derek, Walther, Leslie, Jaza, Lujain, Gu, Hongjie, Agarwal, Mansi, Green, Michael, Moore, Erika, Swerdlow, Steven H, Silveira, Fernanda, Marks, Lianna J, Gratzinger, Dita, Bagg, Adam, Law, Soi Cheng, Gandhi, Maher

“…Post-transplant lymphoproliferative disorders (PTLDs) remain a feared complication of transplantation, with significant morbidity and mortality. The oncogenic…”
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Metagenomic Analysis of DNA Viruses with Targeted Sequence Capture of Canine Lobular Orbital Adenomas and Normal Conjunctiva by Schaefer, Elizabeth A F, Chu, Shirley, Wylie, Kristine M, Wylie, Todd N, Griffith, Obi L, Pearce, Jacqueline W, Johnson, Gayle C, Bryan, Jeffrey N, Flesner, Brian K

“…Our study aims are: (1) to evaluate phenotypically normal canine conjunctival and orbital tissue and tissue from canine lobular orbital adenomas (CLOAs) for…”
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The vaginal eukaryotic DNA virome and preterm birth by Wylie, Kristine M., Wylie, Todd N., Cahill, Alison G., Macones, George A., Tuuli, Methodius G., Stout, Molly J.

“…Despite decades of attempts to link infectious agents to preterm birth, an exact causative microbe or community of microbes remains elusive…”
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Detection of Viruses in Clinical Samples by Use of Metagenomic Sequencing and Targeted Sequence Capture by Wylie, Kristine M, Wylie, Todd N, Buller, Richard, Herter, Brandi, Cannella, Maria T, Storch, Gregory A

“…Metagenomic shotgun sequencing (MSS) is a revolutionary approach to viral diagnostic testing that allows simultaneous detection of a broad range of viruses,…”
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Genome Organization of Canada Goose Coronavirus, A Novel Species Identified in a Mass Die-off of Canada Geese by Papineau, Amber, Berhane, Yohannes, Wylie, Todd N., Wylie, Kristine M., Sharpe, Samuel, Lung, Oliver

“…The complete genome of a novel coronavirus was sequenced directly from the cloacal swab of a Canada goose that perished in a die-off of Canada and Snow geese…”
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The Origin and Evolution of Mutations in Acute Myeloid Leukemia by Welch, John S., Ley, Timothy J., Link, Daniel C., Miller, Christopher A., Larson, David E., Koboldt, Daniel C., Wartman, Lukas D., Lamprecht, Tamara L., Liu, Fulu, Xia, Jun, Kandoth, Cyriac, Fulton, Robert S., McLellan, Michael D., Dooling, David J., Wallis, John W., Chen, Ken, Harris, Christopher C., Schmidt, Heather K., Kalicki-Veizer, Joelle M., Lu, Charles, Zhang, Qunyuan, Lin, Ling, O’Laughlin, Michelle D., McMichael, Joshua F., Delehaunty, Kim D., Fulton, Lucinda A., Magrini, Vincent J., McGrath, Sean D., Demeter, Ryan T., Vickery, Tammi L., Hundal, Jasreet, Cook, Lisa L., Swift, Gary W., Reed, Jerry P., Alldredge, Patricia A., Wylie, Todd N., Walker, Jason R., Watson, Mark A., Heath, Sharon E., Shannon, William D., Varghese, Nobish, Nagarajan, Rakesh, Payton, Jacqueline E., Baty, Jack D., Kulkarni, Shashikant, Klco, Jeffery M., Tomasson, Michael H., Westervelt, Peter, Walter, Matthew J., Graubert, Timothy A., DiPersio, John F., Ding, Li, Mardis, Elaine R., Wilson, Richard K.

“…Most mutations in cancer genomes are thought to be acquired after the initiating event, which may cause genomic instability and drive clonal evolution…”
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Host Gene Expression in Nose and Blood for the Diagnosis of Viral Respiratory Infection by Yu, Jinsheng, Peterson, Derick R, Baran, Andrea M, Bhattacharya, Soumyaroop, Wylie, Todd N, Falsey, Ann R, Mariani, Thomas J, Storch, Gregory A

“…Recently there has been a growing interest in the potential for host transcriptomic analysis to augment the diagnosis of infectious diseases. We compared nasal…”
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Chronic villitis of unknown etiology: Investigations into viral pathogenesis by Ernst, Linda M., Bockoven, Crystal, Freedman, Alexa, Wang, Vivien, Pellerite, Matthew, Wylie, Todd N., Wylie, Kristine M.

“…Chronic villitis of unknown etiology (VUE) is a chronic inflammatory lesion of third trimester placenta, which contributes to major adverse obstetric outcomes…”
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