Search Results - "Wylie, Dennis"

Molecular mimicry as a mechanism of viral immune evasion and autoimmunity by Maguire, Cole, Wang, Chumeng, Ramasamy, Akshara, Fonken, Cara, Morse, Brinkley, Lopez, Nathan, Wylie, Dennis, Melamed, Esther

“…Mimicry of host protein structures, or ‘molecular mimicry’, is a common mechanism employed by viruses to evade the host’s immune system. Short linear amino…”
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High-Resolution Substrate Specificity Profiling of SARS-CoV‑2 Mpro; Comparison to SARS-CoV Mpro by Yaghi, Rasha M., Andrews, Collin L., Wylie, Dennis C., Iverson, Brent L.

“…The SARS-CoV-2 Mpro protease from COVID-19 cleaves the pp1a and pp2b polyproteins at 11 sites during viral maturation and is the target of Nirmatrelvir, one of…”
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High-Resolution Substrate Specificity Profiling of SARS-CoV-2 M pro ; Comparison to SARS-CoV M pro by Yaghi, Rasha M, Andrews, Collin L, Wylie, Dennis C, Iverson, Brent L

“…The SARS-CoV-2 M protease from COVID-19 cleaves the pp1a and pp2b polyproteins at 11 sites during viral maturation and is the target of Nirmatrelvir, one of…”
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Identification of peptide coatings that enhance diffusive transport of nanoparticles through the tumor microenvironment by Mohanty, Rashmi P, Liu, Xinquan, Kim, Jae Y, Peng, Xiujuan, Bhandari, Sahil, Leal, Jasmim, Arasappan, Dhivya, Wylie, Dennis C, Dong, Tony, Ghosh, Debadyuti

“…In solid tumors, increasing drug penetration promotes their regression and improves the therapeutic index of compounds. However, the heterogeneous…”
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Apobec-mediated retroviral hypermutation in vivo is dependent on mouse strain by Byun, Hyewon, Singh, Gurvani B, Xu, Wendy Kaichun, Das, Poulami, Reyes, Alejandro, Battenhouse, Anna, Wylie, Dennis C, Santiago, Mario L, Lozano, Mary M, Dudley, Jaquelin P

“…Replication of the complex retrovirus mouse mammary tumor virus (MMTV) is antagonized by murine Apobec3 (mA3), a member of the Apobec family of cytidine…”
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Clinical characteristics of Long COVID patients presenting to a dedicated academic post-COVID-19 clinic in Central Texas by Aziz, Rija, Siles, Nadia, Kelley, Mary, Wylie, Dennis, Melamed, Esther, Brode, W. Michael

“…Post-acute sequelae SARS-CoV-2 (PASC), also known as Long COVID, is a complex and widely recognized illness with estimates ranging from 5 to 30% of all…”
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Peptides as surface coatings of nanoparticles that penetrate human cystic fibrosis sputum and uniformly distribute in vivo following pulmonary delivery by Leal, Jasmim, Peng, Xiujuan, Liu, Xinquan, Arasappan, Dhivya, Wylie, Dennis C., Schwartz, Sarah H., Fullmer, Jason J., McWilliams, Bennie C., Smyth, Hugh D.C., Ghosh, Debadyuti

“…Therapeutic delivery of drug and gene delivery systems have to traverse multiple biological barriers to achieve efficacy. Mucosal administration, such as…”
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Covalent JNK Inhibitor, JNK-IN-8, Suppresses Tumor Growth in Triple-Negative Breast Cancer by Activating TFEB- and TFE3-Mediated Lysosome Biogenesis and Autophagy by Soleimani, Milad, Somma, Alexander, Kaoud, Tamer, Goyal, Ria, Bustamante, Jorge, Wylie, Dennis C., Holay, Nisha, Looney, Agnieszka, Giri, Uma, Triplett, Todd, Dalby, Kevin, Kowalski, Jeanne, Eckhardt, S. Gail, Van Den Berg, Carla

“…Abstract The heterogeneity and aggressiveness of triple-negative breast cancer (TNBC) contribute to its early recurrence and metastasis. Despite substantial…”
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SArKS: de novo discovery of gene expression regulatory motif sites and domains by suffix array kernel smoothing by Wylie, Dennis C, Hofmann, Hans A, Zemelman, Boris V

“…Abstract Motivation We set out to develop an algorithm that can mine differential gene expression data to identify candidate cell type-specific DNA regulatory…”
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Nineteen Years of Consistently Positive and Strong Female Mate Preferences despite Individual Variation by Ryan, Michael J, Akre, Karin L, Baugh, Alexander T, Bernal, Ximena E, Lea, Amanda M, Leslie, Caitlin, Still, Meghan B, Wylie, Dennis C, Rand, A Stanley

“…Sexual selection driven by mate choice has generated some of the most astounding diversity in nature, suggesting that population-level preferences should be…”
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Functional Access to Neuron Subclasses in Rodent and Primate Forebrain by Mehta, Preeti, Kreeger, Lauren, Wylie, Dennis C., Pattadkal, Jagruti J., Lusignan, Tara, Davis, Matthew J., Turi, Gergely F., Li, Wen-Ke, Whitmire, Matthew P., Chen, Yuzhi, Kajs, Bridget L., Seidemann, Eyal, Priebe, Nicholas J., Losonczy, Attila, Zemelman, Boris V.

“…Viral vectors enable foreign proteins to be expressed in brains of non-genetic species, including non-human primates. However, viruses targeting specific…”
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miRNA Biomarkers in Cyst Fluid Augment the Diagnosis and Management of Pancreatic Cysts by MATTHAEI, Hanno, WYLIE, Dennis, ADAI, Alex T, HRUBAN, Ralph H, SZAFRANSKA-SCHWARZBACH, Anna E, MAITRA, Anirban, LLOYD, Maura B, DAL MOLIN, Marco, KEMPPAINEN, Jon, MAYO, Skye C, WOLFGANG, Christopher L, SCHULICK, Richard D, LANGFIELD, Laura, ANDRUSS, Bernard F

“…The diagnosis of pancreatic cystic lesions has increased dramatically. Most are benign, whereas some, such as intraductal papillary mucinous neoplasms (IPMN),…”
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Targeted, High-Depth, Next-Generation Sequencing of Cancer Genes in Formalin-Fixed, Paraffin-Embedded and Fine-Needle Aspiration Tumor Specimens by Hadd, Andrew G, Houghton, Jeff, Choudhary, Ashish, Sah, Sachin, Chen, Liangjing, Marko, Adam C, Sanford, Tiffany, Buddavarapu, Kalyan, Krosting, Julie, Garmire, Lana, Wylie, Dennis, Shinde, Rupali, Beaudenon, Sylvie, Alexander, Erik K, Mambo, Elizabeth, Adai, Alex T, Latham, Gary J

“…Implementation of highly sophisticated technologies, such as next-generation sequencing (NGS), into routine clinical practice requires compatibility with…”
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Massively Parallel Selection of NanoCluster Beacons by Kuo, Yu‐An, Jung, Cheulhee, Chen, Yu‐An, Kuo, Hung‐Che, Zhao, Oliver S., Nguyen, Trung D., Rybarski, James R., Hong, Soonwoo, Chen, Yuan‐I, Wylie, Dennis C., Hawkins, John A., Walker, Jada N., Shields, Samuel W. J., Brodbelt, Jennifer S., Petty, Jeffrey T., Finkelstein, Ilya J., Yeh, Hsin‐Chih

“…NanoCluster Beacons (NCBs) are multicolor silver nanocluster probes whose fluorescence can be activated or tuned by a proximal DNA strand called the activator…”
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Filter forensics: microbiota recovery from residential HVAC filters by Maestre, Juan P, Jennings, Wiley, Wylie, Dennis, Horner, Sharon D, Siegel, Jeffrey, Kinney, Kerry A

“…Establishing reliable methods for assessing the microbiome within the built environment is critical for understanding the impact of biological exposures on…”
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eIFiso4G Augments the Synthesis of Specific Plant Proteins Involved in Normal Chloroplast Function by Lellis, Andrew D, Patrick, Ryan M, Mayberry, Laura K, Lorence, Argelia, Campbell, Zachary C, Roose, Johnna L, Frankel, Laurie K, Bricker, Terry M, Hellmann, Hanjo A, Mayberry, Roderick W, Zavala, Ana Solis, Choy, Grace S, Wylie, Dennis C, Abdul-Moheeth, Mustafa, Masood, Adeeb, Prater, Amy G, Van Hoorn, Hailey E, Cole, Nicola A, Browning, Karen S

“…The plant-specific translation initiation complex eIFiso4F is encoded by three genes in Arabidopsis ( )-genes encoding the cap binding protein eIFiso4E ( ) and…”
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Massively Parallel Selection of NanoCluster Beacons (Adv. Mater. 41/2022) by Kuo, Yu‐An, Jung, Cheulhee, Chen, Yu‐An, Kuo, Hung‐Che, Zhao, Oliver S., Nguyen, Trung D., Rybarski, James R., Hong, Soonwoo, Chen, Yuan‐I, Wylie, Dennis C., Hawkins, John A., Walker, Jada N., Shields, Samuel W. J., Brodbelt, Jennifer S., Petty, Jeffrey T., Finkelstein, Ilya J., Yeh, Hsin‐Chih

“…Fluorescent Nanomaterials By repurposing next‐generation sequencing chips, millions of fluorescent NanoCluster Beacons (NCBs) can be screened in a single…”
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A Case Series Exploration of Multi-Regional Expression Heterogeneity in Triple-Negative Breast Cancer Patients by Xu, Qi, Kaur, Jaspreet, Wylie, Dennis, Mittal, Karuna, Li, Hongxiao, Kolachina, Rishab, Aleskandarany, Mohammed, Toss, Michael S., Green, Andrew R., Yang, Jianchen, Yankeelov, Thomas E., Bhattarai, Shristi, Janssen, Emiel A. M., Kong, Jun, Rakha, Emad A., Kowalski, Jeanne, Aneja, Ritu

“…Extensive intratumoral heterogeneity (ITH) is believed to contribute to therapeutic failure and tumor recurrence, as treatment-resistant cell clones can…”
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A Protein Antagonist of Activation-Induced Cytidine Deaminase Encoded by a Complex Mouse Retrovirus by Singh, Gurvani B, Byun, Hyewon, Ali, Almas F, Medina, Frank, Wylie, Dennis, Shivram, Haridha, Nash, Andrea K, Lozano, Mary M, Dudley, Jaquelin P

“…Complex human-pathogenic retroviruses cause high morbidity and mortality worldwide, but resist antiviral drugs and vaccine development due to evasion of the…”
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A novel mean-centering method for normalizing microRNA expression from high-throughput RT-qPCR data by Wylie, Dennis, Shelton, Jeffrey, Choudhary, Ashish, Adai, Alex T

“…Normalization is critical for accurate gene expression analysis. A significant challenge in the quantitation of gene expression from biofluids samples is the…”
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