Search Results - "Wyke, J.A."

Overview — burgeoning promise in metastasis research by Wyke, J.A

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Mutations in v-Src SH3 and catalytic domains that jointly confer temperature-sensitive transformation with minimal temperature-dependent changes in cellular tyrosine phosphorylation by Catling, A.D, Fincham, V.J, Frame, M.C, Haefner, B, Wyke, J.A

“…We have analyzed two functionally significant amino acid alterations encoded by the temperature-sensitive (ts) v-src mutant of Rous sarcoma virus, LA32. The…”
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Genetic analysis of the form and function of the viral src oncogene product by Wyke, J A, Stoker, A W

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Active viral genes in transformed cells lie close to the nuclear cage by Cook, P.R., Lang, J., Hayday, A., Lania, L., Fried, M., Chiswell, D.J., Wyke, J.A.

“…Nuclear DNA is looped by attachment to a matrix or cage. Using nine different lines transformed by polyoma or avian sarcoma virus, we have mapped viral…”
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Infection of rat cells by avian sarcoma virus: factors affecting transformation and subsequent reversion by Wyke, J A, Quade, K

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Comparison of the relative importance of tyrosine-specific vinculin phosphorylation and the loss of surface-associated fibronectin in the morphology of cells transformed by Rous sarcoma virus by Kellie, S, Patel, B, Mitchell, A, Critchley, D.R, Wigglesworth, N.M, Wyke, J.A

“…We have investigated the relative importance of tyrosine-specific phosphorylation of vinculin and the loss of surface-associated fibronectin in the maintenance…”
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Expression of the ASV src gene in hybrids between normal and virally transformed cells: specific suppression occurs in some hybrids but not others by Dyson, P J, Quade, K, Wyke, J A

“…Somatic cell hybrids have been made between clones of rat cells transformed by avian sarcoma virus and rat or mouse cells that are untransformed. Intraspecies…”
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Expression of integrated Rous sarcoma viruses: DNA rearrangements 5′ to the provirus are common in transformed rat cells but not seen in infected but untransformed cells by Green, A.R., Searle, S., Gillespie, D.A., Bissell, M., Wyke, J.A.

“…The study of Rous sarcoma virus (RSV)‐infected rat cell clones offers a novel approach to unravelling the mechanisms controlling eukaryotic gene expression…”
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The chromatin structure of Rous sarcoma proviruses is changed by factors that act in trans in cell hybrids by Dyson, P.J., Cook, P.R., Searle, S., Wyke, J.A.

“…In several lines of Rous sarcoma virus (RSV)‐transformed rat cells the proviruses are in a configuration typical of active eukaryotic genes. They are sensitive…”
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Altered pathogenicity of avian myelocytomatosis (MC29) viruses with mutations in the v-myc gene by Enrietto, P J, Hayman, M J, Ramsay, G M, Wyke, J A, Payne, L N

“…Avian myelocytomatosis virus MC29 inoculated into the wing web of 1-day-old Brown Leghorn chickens causes a high incidence of tumors, predominantly…”
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Functional domains of the pp60v-src protein as revealed by analysis of temperature-sensitive rous sarcoma virus mutants by Stoker, A.W, Enrietto, P.J, Wyke, J.A

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Effects of inhibitors of lipid synthesis on the replication of Rous sarcoma virus. A specific effect of cerulenin on the processing of major non-glycosylated viral structural proteins by Goldfine, H, Harley, J B, Wyke, J A

“…The effects of two inhibitors of lipid biosynthesis on the replication of Rous sarcoma virus Prague C strain in chick embryo fibroblasts have been examined in…”
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Genetic recombination in Rous sarcoma virus: the genesis of recombinants and lack of evidence for linkage between pol, env and src genes in three factor crosses by Wyke, J.A, Beamand, J.A

“…Imperial Cancer Research Fund Laboratories, Lincoln's Inn Fields, London WC2A 3PX, U.K. Three factor crosses were performed between Rous sarcoma virus mutants…”
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Cell surface and metabolic labelling of the proteins of normal and transformed chicken cells by Critchley, D R, Wyke, J A, Hynes, R O

“…We have studied the surface proteins of normal and transformed chick cells using four-labelling techniques with different specificities, (a) lactoperoxidase…”
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Glycolipids of chick embryo fibroblasts infected with temperature-sensitive mutants of avian sarcoma viruses by Hakomori, S I, Wyke, J A, Vogt, P K

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The genetics of C-type RNA tumor viruses by Wyke, J A

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Restriction of replication of Rous sarcoma virus mediated by the src region of the genome: analysis of the formation and integration of viral DNA and the effects of conditional and nonconditional mutations in src by Neiman, P E, Stone, J, Gilbert, L, Fincham, V J, McMillin-Helsel, C, Wyke, J A

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