Search Results - "Wurm, A A"

Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid by Kukat, Christian, Davies, Karen M., Wurm, Christian A., Spåhr, Henrik, Bonekamp, Nina A., Kühl, Inge, Joos, Friederike, Polosa, Paola Loguercio, Park, Chan Bae, Posse, Viktor, Falkenberg, Maria, Jakobs, Stefan, Kühlbrandt, Werner, Larsson, Nils-Göran

“…Mammalian mitochondrial DNA (mtDNA) is packaged by mitochondrial transcription factor A (TFAM) into mitochondrial nucleoids that are of key importance in…”
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MINFLUX nanometer-scale 3D imaging and microsecond-range tracking on a common fluorescence microscope by Schmidt, Roman, Weihs, Tobias, Wurm, Christian A., Jansen, Isabelle, Rehman, Jasmin, Sahl, Steffen J., Hell, Stefan W.

“…The recently introduced minimal photon fluxes (MINFLUX) concept pushed the resolution of fluorescence microscopy to molecular dimensions. Initial…”
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Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA by Kukat, Christian, Wurm, Christian A, Spåhr, Henrik, Falkenberg, Maria, Larsson, Nils-Göran, Jakobs, Stefan

“…Mammalian mtDNA is packaged in DNA-protein complexes denoted mitochondrial nucleoids. The organization of the nucleoid is a very fundamental question in…”
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Coaligned Dual-Channel STED Nanoscopy and Molecular Diffusion Analysis at 20 nm Resolution by Göttfert, Fabian, Wurm, Christian A., Mueller, Veronika, Berning, Sebastian, Cordes, Volker C., Honigmann, Alf, Hell, Stefan W.

“…We report on a fiber laser-based stimulated emission-depletion microscope providing down to ∼20 nm resolution in raw data images as well as 15–19 nm diameter…”
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Predicting the membrane permeability of organic fluorescent probes by the deep neural network based lipophilicity descriptor DeepFl-LogP by Soliman, Kareem, Grimm, Florian, Wurm, Christian A., Egner, Alexander

“…Light microscopy has become an indispensable tool for the life sciences, as it enables the rapid acquisition of three-dimensional images from the interior of…”
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Spherical nanosized focal spot unravels the interior of cells by Wurm, Christian A, Engelhardt, Johann, Egner, Alexander, Hell, Stefan W, Jakobs, Stefan, Schmidt, Roman

“…A fluorescence microscope relying entirely on focused light allows the generation of spherical focal fluorescence spots much smaller than the wavelength of…”
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Long Non-coding RNAs as Functional and Structural Chromatin Modulators in Acute Myeloid Leukemia by Wurm, Alexander A., Pina, Cristina

“…Acute myeloid leukemia is a hematopoietic neoplasm of dismal prognosis that results from the accumulation of immature myeloid blasts in the bone marrow and the…”
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NF-κB/STAT5/miR-155 network targets PU.1 in FLT3-ITD-driven acute myeloid leukemia by Gerloff, D, Grundler, R, Wurm, A A, Bräuer-Hartmann, D, Katzerke, C, Hartmann, J-U, Madan, V, Müller-Tidow, C, Duyster, J, Tenen, D G, Niederwieser, D, Behre, G

“…Almost 30% of all acute myeloid leukemias (AML) are associated with an internal tandem duplication (ITD) in the juxtamembrane domain of FMS-like tyrosine…”
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STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria by Jans, Daniel C., Wurm, Christian A., Riedel, Dietmar, Wenzel, Dirk, Stagge, Franziska, Deckers, Markus, Rehling, Peter, Jakobs, Stefan

“…The mitochondrial inner membrane organizing system (MINOS) is a conserved large hetero-oligomeric protein complex in the mitochondrial inner membrane, crucial…”
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Organization of Mitochondrial Gene Expression in Two Distinct Ribosome-Containing Assemblies by Kehrein, Kirsten, Schilling, Ramon, Möller-Hergt, Braulio Vargas, Wurm, Christian A., Jakobs, Stefan, Lamkemeyer, Tobias, Langer, Thomas, Ott, Martin

“…Mitochondria contain their own genetic system that provides subunits of the complexes driving oxidative phosphorylation. A quarter of the mitochondrial…”
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Two-color nanoscopy of three-dimensional volumes by 4Pi detection of stochastically switched fluorophores by Aquino, Daniel, Schönle, Andreas, Geisler, Claudia, Middendorff, Claas v, Wurm, Christian A, Okamura, Yosuke, Lang, Thorsten, Hell, Stefan W, Egner, Alexander

“…Analyzing the first and higher-order moments of the diffraction spot of a 4Pi fluorescence detection scheme facilitates two-color, three-dimensional…”
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SNAP-, CLIP- and Halo-tag labelling of budding yeast cells by Stagge, Franziska, Mitronova, Gyuzel Y, Belov, Vladimir N, Wurm, Christian A, Jakobs, Stefan

“…Fluorescence microscopy of the localization and the spatial and temporal dynamics of specifically labelled proteins is an indispensable tool in cell biology…”
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Eastern Australian Farmers Managing and Thinking Differently: Innovative Adaptation Cycles by McKenzie, David K., Joyce, Janine, Zander, Kerstin K., Wurm, Penelope A. S., Caudwell, Kim M.

“…The uncertainty of climate change is a significant challenge prompting Australian farmers to create different thinking and different management systems that…”
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Rhodamines NN: A Novel Class of Caged Fluorescent Dyes by Belov, Vladimir N, Wurm, Christian A, Boyarskiy, Vadim P, Jakobs, Stefan, Hell, Stefan W

“…A bright future: The reaction of diazomethane with acid chlorides obtained from N,N,N′,N′‐tetraalkylrhodamines affords…”
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Differential protein distributions define two sub-compartments of the mitochondrial inner membrane in yeast by Wurm, Christian A., Jakobs, Stefan

“…The mitochondrial inner membrane exhibits a complex topology. Its infolds, the cristae membranes, are contiguous with the inner boundary membrane (IBM), which…”
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Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient by Wurm, Christian A, Neumann, Daniel, Lauterbach, Marcel A, Harke, Benjamin, Egner, Alexander, Hell, Stefan W, Jakobs, Stefan

“…The translocase of the mitochondrial outer membrane (TOM) complex is the main import pore for nuclear-encoded proteins into mitochondria, yet little is known…”
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Three dimensional live-cell STED microscopy at increased depth using a water immersion objective by Heine, Jörn, Wurm, Christian A, Keller-Findeisen, Jan, Schönle, Andreas, Harke, Benjamin, Reuss, Matthias, Winter, Franziska R, Donnert, Gerald

“…Modern fluorescence superresolution microscopes are capable of imaging living cells on the nanometer scale. One of those techniques is stimulated emission…”
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Stimulated Emission Depletion Nanoscopy of Living Cells Using SNAP-Tag Fusion Proteins by Hein, Birka, Willig, Katrin I., Wurm, Christian A., Westphal, Volker, Jakobs, Stefan, Hell, Stefan W.

“…We show far-field fluorescence nanoscopy of different structural elements labeled with an organic dye within living mammalian cells. The diffraction barrier…”
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Far-Red Emitting Fluorescent Dyes for Optical Nanoscopy: Fluorinated Silicon-Rhodamines (SiRF Dyes) and Phosphorylated Oxazines by Kolmakov, Kirill, Hebisch, Elke, Wolfram, Thomas, Nordwig, Lars A., Wurm, Christian A., Ta, Haisen, Westphal, Volker, Belov, Vladimir N., Hell, Stefan W.

“…Far‐red emitting fluorescent dyes for optical microscopy, stimulated emission depletion (STED), and ground‐state depletion (GSDIM) super‐resolution microscopy…”
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Raman microscopic spectroscopy as a diagnostic tool to detect Staphylococcus epidermidis in bone grafts by Wurm, A., Kühn, J., Kugel, K., Putzer, D., Arora, R., Coraça-Huber, D.C., Zelger, P., Badzoka, J., Kappacher, C., Huck, C.W., Pallua, J.D.

“…[Display omitted] •Raman microscopic spectroscopy can be a reliable, cost-effective, and quick alternative for detecting Staphylococcus epidermidis in human…”
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