Search Results - "Wunderling, Klaus"
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Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation
Published in Immunity (Cambridge, Mass.) (14-04-2020)“…Innate lymphoid cells (ILCs) play an important role in the control and maintenance of barrier immunity. However, chronic activation of ILCs results in…”
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Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction
Published in Journal of lipid research (01-01-2017)“…1-Deoxysphingolipids (deoxySLs) are atypical sphingolipids that are elevated in the plasma of patients with type 2 diabetes and hereditary sensory and…”
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Hepatic synthesis of triacylglycerols containing medium-chain fatty acids is dominated by diacylglycerol acyltransferase 1 and efficiently inhibited by etomoxir
Published in Molecular metabolism (Germany) (01-03-2021)“…Medium-chain fatty acids (MCFAs) play an increasing role in human nutrition. In the liver, one fraction is used for synthesis of MCFA-containing…”
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Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis
Published in Molecular metabolism (Germany) (01-07-2024)“…The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor regulating xenobiotic responses as well as physiological metabolism. Dietary AhR…”
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Multiplexed and single cell tracing of lipid metabolism
Published in Nature methods (01-11-2019)“…Cellular lipid metabolism is a complex network process comprising dozens of enzymes, multiple organelles and more than a thousand lipid species. Tracing…”
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Triglyceride cycling enables modification of stored fatty acids
Published in Nature metabolism (01-04-2023)“…Triglyceride cycling is the process of continuous degradation and re-synthesis of triglyceride in cellular stores. We show in 3T3-L1 adipocytes that…”
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Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation
Published in Immunity (Cambridge, Mass.) (19-05-2020)Get full text
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Creld2 function during unfolded protein response is essential for liver metabolism homeostasis
Published in The FASEB journal (01-10-2021)“…The unfolded protein response (UPR) is associated with hepatic metabolic function, yet it is not well understood how endoplasmic reticulum (ER) disturbance…”
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Temperature Differences between Arctic and Alpine Meadows and Their Ecological Significance
Published in Oecologia (01-01-1970)Get full text
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