Search Results - "Wun-Jae Kim"
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1
Role of Exosomal miRNA in Bladder Cancer: A Promising Liquid Biopsy Biomarker
Published in International journal of molecular sciences (08-02-2021)“…Bladder cancer (BCa) is the most prevalent neoplasia of the urinary tract. Unfortunately, limited improvements in effective BCa management have meant that it…”
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2
TCF4 induces enzalutamide resistance via neuroendocrine differentiation in prostate cancer
Published in PloS one (19-09-2019)“…In treating patients with castration resistant prostate cancer (CRPC), enzalutamide, the second-generation androgen receptor (AR) antagonist, is an accepted…”
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3
Anti-Proliferative and Pro-Apoptotic Effects of Licochalcone A through ROS-Mediated Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells
Published in International journal of molecular sciences (05-08-2019)“…Licochalcone A (LCA) is a chalcone that is predominantly found in the root of species, which is widely used as an herbal medicine. Although previous studies…”
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4
Urinary cell‐free microRNA biomarker could discriminate bladder cancer from benign hematuria
Published in International journal of cancer (15-01-2019)“…The most common symptom of bladder cancer (BC) is hematuria. However, not all patients with hematuria are diagnosed with BC. Here, we explored a novel method…”
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5
HSPA6 augments garlic extract-induced inhibition of proliferation, migration, and invasion of bladder cancer EJ cells; Implication for cell cycle dysregulation, signaling pathway alteration, and transcription factor-associated MMP-9 regulation
Published in PloS one (10-02-2017)“…Although recent studies have demonstrated the anti-tumor effects of garlic extract (GE), the exact molecular mechanism is still unclear. In this study, we…”
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6
Molecular biomarkers in urothelial bladder cancer
Published in Cancer science (01-04-2008)“…Bladder cancers are a mixture of heterogeneous cell populations, and numerous factors are likely to be involved in dictating their recurrence, progression, and…”
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7
Activation of EZH2 and SUZ12 Regulated by E2F1 Predicts the Disease Progression and Aggressive Characteristics of Bladder Cancer
Published in Clinical cancer research (01-12-2015)“…Previous study identified E2F1 as a key mediator of non-muscle-invasive bladder cancer (NMIBC) progression. The aim of this study was to identify the…”
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HOXA9, ISL1 and ALDH1A3 methylation patterns as prognostic markers for nonmuscle invasive bladder cancer: Array‐based DNA methylation and expression profiling
Published in International journal of cancer (01-09-2013)“…DNA methylation patterns are associated with the development and prognosis of cancer. The aim of this study was to identify novel methylation markers for the…”
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9
Induction of Apoptosis by Coptisine in Hep3B Hepatocellular Carcinoma Cells through Activation of the ROS-Mediated JNK Signaling Pathway
Published in International journal of molecular sciences (31-07-2020)“…Hepatocellular carcinoma (HCC) has a high mortality rate worldwide, and treatment is very limited due to its high recurrence and low diagnosis rate, and…”
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10
Predictive value of progression-related gene classifier in primary non-muscle invasive bladder cancer
Published in Molecular cancer (08-01-2010)“…While several molecular markers of bladder cancer prognosis have been identified, the limited value of current prognostic markers has created the need for new…”
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11
Bisphenol A regulates bladder cells responses via control of G2/M‐phase cell cycle, apoptotic signaling, MAPK pathway, and transcription factor‐associated MMP modulation
Published in Journal of biochemical and molecular toxicology (01-03-2024)“…Bisphenol A (BPA), an exogenous endocrine‐disrupting chemical, is widely used to produce polycarbonate plastics. The widely used BPA has been detected in human…”
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12
Expression Signature of E2F1 and Its Associated Genes Predict Superficial to Invasive Progression of Bladder Tumors
Published in Journal of clinical oncology (01-06-2010)“…In approximately 20% of patients with superficial bladder tumors, the tumors progress to invasive tumors after treatment. Current methods of predicting the…”
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13
The age-adjusted Charlson comorbidity index as a predictor of overall survival of surgically treated non-metastatic clear cell renal cell carcinoma
Published in Journal of cancer research and clinical oncology (01-01-2020)“…Purpose No study has evaluated the prognostic impact of the age-adjusted Charlson comorbidity index (AACI) in those with renal cell carcinoma (RCC). This study…”
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14
Anti-inflammatory effects of genistein via suppression of the toll-like receptor 4-mediated signaling pathway in lipopolysaccharide-stimulated BV2 microglia
Published in Chemico-biological interactions (05-04-2014)“…•Genistein attenuates production of pro-inflammatory mediators and cytokines in LPS-activated BV2 microglia.•Genistein exhibits anti-inflammatory properties…”
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15
The p21-activated kinase 4-Slug transcription factor axis promotes epithelial−mesenchymal transition and worsens prognosis in prostate cancer
Published in Oncogene (01-09-2018)“…Epithelial−mesenchymal transition (EMT) facilitates cancer invasion and metastasis and thus accelerates cancer progression. p21-activated kinase 4 (PAK4) is a…”
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16
Anti-Metastatic Effect of Pyruvate Dehydrogenase Kinase 4 Inhibition in Bladder Cancer via the ERK, SRC, and JNK Pathways
Published in International journal of molecular sciences (01-11-2022)“…Bladder cancer is a common global cancer with a high percentage of metastases and high mortality rate. Thus, it is necessary to identify new biomarkers that…”
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17
Utility of a Molecular Signature for Predicting Recurrence and Progression in Non-Muscle-Invasive Bladder Cancer Patients: Comparison with the EORTC, CUETO and 2021 EAU Risk Groups
Published in International journal of molecular sciences (21-11-2022)“…To evaluate the utility of different risk assessments in non-muscle-invasive bladder cancer (NMIBC) patients, a total of 178 NMIBC patients from Chungbuk…”
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18
Bisphenol A modulates proliferation, apoptosis, and wound healing process of normal prostate cells: Involvement of G2/M-phase cell cycle arrest, MAPK signaling, and transcription factor-mediated MMP regulation
Published in Ecotoxicology and environmental safety (01-01-2023)“…Bisphenol A (BPA) is commonly used to produce epoxy resins and polycarbonate plastics. BPA is an endocrine-disrupting chemical that is leaked from the polymer…”
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19
Dihydrotestosterone Increases Cytotoxic Activity of Macrophages on Prostate Cancer Cells via TRAIL
Published in Endocrinology (Philadelphia) (01-09-2019)“…Although androgen deprivation therapy (ADT) and immunotherapy are potential treatment options in men with metastatic prostate cancer (CaP), androgen has…”
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20
Association between De Ritis ratio (aspartate aminotransferase/alanine aminotransferase) and oncological outcomes in bladder cancer patients after radical cystectomy
Published in BMC urology (24-01-2019)“…New biological prognostic predictors have been studied; however, some factors have limited clinical application due to tissue-specific expression and high…”
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