Search Results - "Wu Chou"

AZD9291 in EGFR Inhibitor–Resistant Non–Small-Cell Lung Cancer by Jänne, Pasi A, Yang, James Chih-Hsin, Kim, Dong-Wan, Planchard, David, Ohe, Yuichiro, Ramalingam, Suresh S, Ahn, Myung-Ju, Kim, Sang-We, Su, Wu-Chou, Horn, Leora, Haggstrom, Daniel, Felip, Enriqueta, Kim, Joo-Hang, Frewer, Paul, Cantarini, Mireille, Brown, Kathryn H, Dickinson, Paul A, Ghiorghiu, Serban, Ranson, Malcolm

“…AZD9291, an irreversible inhibitor of epidermal growth factor receptor, was associated with tumor responses in the majority of patients with advanced…”
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Overall Survival with Osimertinib in Resected EGFR-Mutated NSCLC by Tsuboi, Masahiro, Herbst, Roy S., John, Thomas, Kato, Terufumi, Majem, Margarita, Grohé, Christian, Wang, Jie, Goldman, Jonathan W., Lu, Shun, Su, Wu-Chou, de Marinis, Filippo, Shepherd, Frances A., Lee, Ki Hyeong, Le, Nhieu Thi, Dechaphunkul, Arunee, Kowalski, Dariusz, Poole, Lynne, Bolanos, Ana, Rukazenkov, Yuri, Wu, Yi-Long

“…Patients with resected, EGFR -mutated, stage IB to IIIA NSCLC were randomly assigned to receive adjuvant osimertinib or placebo for 3 years. The 5-year overall…”
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Osimertinib plus savolitinib in patients with EGFR mutation-positive, MET-amplified, non-small-cell lung cancer after progression on EGFR tyrosine kinase inhibitors: interim results from a multicentre, open-label, phase 1b study by Sequist, Lecia V, Han, Ji-Youn, Ahn, Myung-Ju, Cho, Byoung Chul, Yu, Helena, Kim, Sang-We, Yang, James Chih-Hsin, Lee, Jong Seok, Su, Wu-Chou, Kowalski, Dariusz, Orlov, Sergey, Cantarini, Mireille, Verheijen, Remy B, Mellemgaard, Anders, Ottesen, Lone, Frewer, Paul, Ou, Xiaoling, Oxnard, Geoffrey

“…Preclinical data suggest that EGFR tyrosine kinase inhibitors (TKIs) plus MET TKIs are a possible treatment for EGFR mutation-positive lung cancers with…”
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Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma With EGFR Mutations by SEQUIST, Lecia V, YANG, James Chih-Hsin, SU, Wu-Chou, BENNOUNA, Jaafar, KATO, Terufumi, GORBUNOVA, Vera, KI HYEONG LEE, SHAH, Riyaz, MASSEY, Dan, ZAZULINA, Victoria, SHAHIDI, Mehdi, SCHULER, Martin, YAMAMOTO, Nobuyuki, O'BYRNE, Kenneth, HIRSH, Vera, MOK, Tony, GEATER, Sarayut Lucien, ORLOV, Sergey, TSAI, Chun-Ming, BOYER, Michael

“…The LUX-Lung 3 study investigated the efficacy of chemotherapy compared with afatinib, a selective, orally bioavailable ErbB family blocker that irreversibly…”
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Osimertinib in Pretreated T790M-Positive Advanced Non-Small-Cell Lung Cancer: AURA Study Phase II Extension Component by Yang, James Chih-Hsin, Ahn, Myung-Ju, Kim, Dong-Wan, Ramalingam, Suresh S, Sequist, Lecia V, Su, Wu-Chou, Kim, Sang-We, Kim, Joo-Hang, Planchard, David, Felip, Enriqueta, Blackhall, Fiona, Haggstrom, Daniel, Yoh, Kiyotaka, Novello, Silvia, Gold, Kathryn, Hirashima, Tomonori, Lin, Chia-Chi, Mann, Helen, Cantarini, Mireille, Ghiorghiu, Serban, Jänne, Pasi A

“…Purpose Osimertinib is an irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) selective for both EGFR-TKI sensitizing ( EGFRm)…”
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Phase 1 study of capmatinib in MET‐positive solid tumor patients: Dose escalation and expansion of selected cohorts by Bang, Yung‐Jue, Su, Wu‐Chou, Schuler, Martin, Nam, Do‐Hyun, Lim, Wan Teck, Bauer, Todd M., Azaro, Analia, Poon, Ronnie Tung Ping, Hong, David, Lin, Chia‐Chi, Akimov, Mikhail, Ghebremariam, Samson, Zhao, Sylvia, Giovannini, Monica, Ma, Brigette

“…Capmatinib is an oral, ATP‐competitive, and highly potent, type 1b MET inhibitor. Herein, we report phase 1 dose‐escalation results for capmatinib in advanced…”
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A roadmap for traffic engineering in SDN-OpenFlow networks by Akyildiz, Ian F., Lee, Ahyoung, Wang, Pu, Luo, Min, Chou, Wu

“…Software Defined Networking (SDN) is an emerging networking paradigm that separates the network control plane from the data forwarding plane with the promise…”
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Efficacy and Safety of Patritumab Deruxtecan (HER3-DXd) in EGFR Inhibitor-Resistant, EGFR -Mutated Non-Small Cell Lung Cancer by Jänne, Pasi A, Baik, Christina, Su, Wu-Chou, Johnson, Melissa L, Hayashi, Hidetoshi, Nishio, Makoto, Kim, Dong-Wan, Koczywas, Marianna, Gold, Kathryn A, Steuer, Conor E, Murakami, Haruyasu, Yang, James Chih-Hsin, Kim, Sang-We, Vigliotti, Michele, Shi, Rong, Qi, Zhenhao, Qiu, Yang, Zhao, Lihui, Sternberg, David, Yu, Channing, Yu, Helena A

“…Receptor tyrosine-protein kinase ERBB3 (HER3) is expressed in most -mutated lung cancers but is not a known mechanism of resistance to EGFR inhibitors…”
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A ternary nanostructured α-Fe2O3/Au/TiO2 photoanode with reconstructed interfaces for efficient photoelectrocatalytic water splitting by Fu, Yanming, Dong, Chung-Li, Zhou, Wu, Lu, Ying-Rui, Huang, Yu-Cheng, Liu, Ya, Guo, Penghui, Zhao, Liang, Chou, Wu-Ching, Shen, Shaohua

“…[Display omitted] •A ternary nanostructured α-Fe2O3/Au/TiO2 photoanode is fabricated.•The photocurrent density is increased by ∼4-folds for…”
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Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials by Yang, James Chih-Hsin, Prof, Wu, Yi-Long, Prof, Schuler, Martin, Prof, Sebastian, Martin, MD, Popat, Sanjay, FRCP, Yamamoto, Nobuyuki, Prof, Zhou, Caicun, Prof, Hu, Cheng-Ping, Prof, O'Byrne, Kenneth, Prof, Feng, Jifeng, Prof, Lu, Shun, Prof, Huang, Yunchao, Prof, Geater, Sarayut L, MD, Lee, Kye Young, Prof, Tsai, Chun-Ming, Prof, Gorbunova, Vera, Prof, Hirsh, Vera, Prof, Bennouna, Jaafar, Prof, Orlov, Sergey, Prof, Mok, Tony, Prof, Boyer, Michael, Prof, Su, Wu-Chou, Prof, Lee, Ki Hyeong, Prof, Kato, Terufumi, MD, Massey, Dan, MSc, Shahidi, Mehdi, MD, Zazulina, Victoria, MD, Sequist, Lecia V, MD

“…Summary Background We aimed to assess the effect of afatinib on overall survival of patients with EGFR mutation-positive lung adenocarcinoma through an…”
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Iron oxide@chlorophyll clustered nanoparticles eliminate bladder cancer by photodynamic immunotherapy-initiated ferroptosis and immunostimulation by Chin, Yu-Cheng, Yang, Li-Xing, Hsu, Fei-Ting, Hsu, Che-Wei, Chang, Te-Wei, Chen, Hsi-Ying, Chen, Linda Yen-Chien, Chia, Zi Chun, Hung, Chun-Hua, Su, Wu-Chou, Chiu, Yi-Chun, Huang, Chih-Chia, Liao, Mei-Yi

“…Abstract The escape of bladder cancer from immunosurveillance causes monotherapy to exhibit poor efficacy; therefore, designing a multifunctional nanoparticle…”
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Uterine leiomyoma is associated with the risk of developing endometriosis: A nationwide cohort study involving 156,195 women by Lin, Kent Yu-Hsien, Yang, Chih-Yi, Lam, Alan, Chang, Cherry Yin-Yi, Lin, Wu-Chou

“…Evidence for an association between uterine leiomyoma and increased risk of endometriosis is limited by small sample sizes and short follow-up periods. We…”
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Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial by Miller, Vincent A, Prof, Hirsh, Vera, MD, Cadranel, Jacques, Prof, Chen, Yuh-Min, MD, Park, Keunchil, Prof, Kim, Sang-We, Prof, Zhou, Caicun, Prof, Su, Wu-Chou, Prof, Wang, Mengzhao, Prof, Sun, Yan, Prof, Heo, Dae Seog, Prof, Crino, Lucio, Prof, Tan, Eng-Huat, MD, Chao, Tsu-Yi, Prof, Shahidi, Mehdi, MD, Cong, Xiuyu Julie, PhD, Lorence, Robert M, MD, Yang, James Chih-Hsin, Prof

“…Summary Background Afatinib, an irreversible ErbB-family blocker, has shown preclinical activity when tested in EGFR mutant models with mutations that confer…”
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Elucidating Quantum Confinement in Graphene Oxide Dots Based On Excitation-Wavelength-Independent Photoluminescence by Yeh, Te-Fu, Huang, Wei-Lun, Chung, Chung-Jen, Chiang, I-Ting, Chen, Liang-Che, Chang, Hsin-Yu, Su, Wu-Chou, Cheng, Ching, Chen, Shean-Jen, Teng, Hsisheng

“…Investigating quantum confinement in graphene under ambient conditions remains a challenge. In this study, we present graphene oxide quantum dots (GOQDs) that…”
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The simultaneous electrochemical detection of ascorbic acid, dopamine, and uric acid using graphene/size-selected Pt nanocomposites by Sun, Chia-Liang, Lee, Hsin-Hsien, Yang, Jen-Ming, Wu, Ching-Chou

“…In this study, a graphene/Pt-modified glassy carbon (GC) electrode was created to simultaneously characterize ascorbic acid (AA), dopamine (DA), and uric acid…”
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Phase Ib/II Study of Capmatinib (INC280) Plus Gefitinib After Failure of Epidermal Growth Factor Receptor (EGFR) Inhibitor Therapy in Patients With EGFR-Mutated, MET Factor-Dysregulated Non-Small-Cell Lung Cancer by Wu, Yi-Long, Zhang, Li, Kim, Dong-Wan, Liu, Xiaoqing, Lee, Dae Ho, Yang, James Chih-Hsin, Ahn, Myung-Ju, Vansteenkiste, Johan F, Su, Wu-Chou, Felip, Enriqueta, Chia, Vincent, Glaser, Sabine, Pultar, Philippe, Zhao, Sylvia, Peng, Bin, Akimov, Mikhail, Tan, Daniel S W

“…MET dysregulation occurs in up to 26% of non-small-cell lung cancers (NSCLCs) after epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI)…”
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Prognostic Value of Whole-Body Total Lesion Glycolysis at Pretreatment FDG PET/CT in Non―Small Cell Lung Cancer by CHEN, Helen H. W, CHIU, Nan-Tsing, SU, Wu-Chou, GUO, How-Ran, LEE, Bi-Fang

“…To determine whether whole-body total lesion glycolysis (TLG), which combines volumetric and metabolic information from fluorine 18 fluorodeoxyglucose (FDG)…”
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EIF2AK2 Missense Variants Associated with Early Onset Generalized Dystonia by Kuipers, Demy J. S., Mandemakers, Wim, Lu, Chin‐Song, Olgiati, Simone, Breedveld, Guido J., Fevga, Christina, Tadic, Vera, Carecchio, Miryam, Osterman, Bradley, Sagi‐Dain, Lena, Wu‐Chou, Yah‐Huei, Chen, Chiung C., Chang, Hsiu‐Chen, Wu, Shey‐Lin, Yeh, Tu‐Hsueh, Weng, Yi‐Hsin, Elia, Antonio E., Panteghini, Celeste, Marotta, Nicolas, Pauly, Martje G., Kühn, Andrea A., Volkmann, Jens, Lace, Baiba, Meijer, Inge A., Kandaswamy, Krishna, Quadri, Marialuisa, Garavaglia, Barbara, Lohmann, Katja, Bauer, Peter, Mencacci, Niccolò E., Lubbe, Steven J., Klein, Christine, Bertoli‐Avella, Aida M., Bonifati, Vincenzo

“…Objective The study was undertaken to identify a monogenic cause of early onset, generalized dystonia. Methods Methods consisted of genome‐wide linkage…”
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The impact of EGFR mutations on the incidence and survival of stages I to III NSCLC patients with subsequent brain metastasis by Chang, Wei-Yuan, Wu, Yi-Lin, Su, Po-Lan, Yang, Szu-Chun, Lin, Chien-Chung, Su, Wu-Chou

“…Previous studies have demonstrated the association between EGFR mutations and distant metastasis. However, the association for subsequent brain metastasis (BM)…”
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Research challenges for traffic engineering in software defined networks by Akyildiz, Ian F., Ahyoung Lee, Pu Wang, Min Luo, Wu Chou

“…SDN is an emerging networking paradigm that separates the network control plane from the data forwarding plane with the promise to dramatically improve network…”
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