Search Results - "Wu, Zuotian"
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The Effects and Mechanisms of Exercise on the Treatment of Depression
Published in Frontiers in psychiatry (05-11-2021)“…Background: It is necessary to seek alternative therapies for depression, because side effects of medications lead to poor adherence and some patients do not…”
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Brief Maternal Separation Promotes Resilience to Anxiety-like and Depressive-like Behaviors in Female C57BL/6J Offspring with Imiquimod-Induced Psoriasis
Published in Brain sciences (15-09-2022)“…Background: Psoriasis is a common chronic inflammatory skin disease that often causes depression. Early life experience affects brain development and relates…”
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Neurogenic hypothesis of positive psychology in stress-induced depression: Adult hippocampal neurogenesis, neuroinflammation, and stress resilience
Published in International immunopharmacology (01-08-2021)“…•Stress-induced neuroinflammation affects AHN related pattern separation.•Neuroprotection is a self-protection measure of the brain against…”
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4
Long-term maternal separation potentiates depressive-like behaviours and neuroinflammation in adult male C57/BL6J mice
Published in Pharmacology, biochemistry and behavior (01-09-2020)“…Early life experience is closely related to depression caused by stress in adulthood. Early life experience, including maternal separation (MS), has been shown…”
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5
Perinatal running training reversed postnatal anxiety and depressive-like behavior and cognitive impairment in mice following prenatal subchronic variable stress
Published in Pharmacology, biochemistry and behavior (01-12-2024)“…Pregnancy is a very complex and highly stressful time in women. Despite the high prevalence of postpartum depression, more than 50 % of mothers are undiagnosed…”
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Brief Pup Separation in Lactation Confers Stress Resistance with Increased Prolactin and Adult Hippocampal Neurogenesis in Postpartum C57BL/6J Dams
Published in Neurochemical research (01-11-2024)“…Prolactin (PRL) assumes a pivotal role during the postpartum phase, particularly within the hippocampus—a region densely populated with receptors for stress…”
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Brief postpartum separation from offspring promotes resilience to lipopolysaccharide challenge-induced anxiety and depressive-like behaviors and inhibits neuroinflammation in C57BL/6J dams
Published in Brain, behavior, and immunity (01-07-2021)“…•LPS immune challenge resulted in depressive-like behaviors and enhanced neuroinflammation expression in dams.•Brief postpartum separation from offspring…”
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PI3K/AKT/GSK3β/CRMP-2-mediated neuroplasticity in depression induced by stress
Published in Neuroreport (17-10-2018)“…Early neurodevelopmental dysplasia or disorder is an important stimulus for depression, but early stress can easily damage nerve development and lead to…”
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Sex-dependent impact of different degrees of maternal separation experience on OFT behavioral performances after adult chronic unpredictable mild stress exposure in rats
Published in Physiology & behavior (01-10-2018)“…Early-life social-environmental factors are important for normal development, and different degrees of early-life stress experience have different impacts on…”
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10
Intermittent hypoxia exacerbated depressive and anxiety-like behaviors in the bleomycin-induced pulmonary fibrosis mice
Published in Brain research bulletin (15-06-2023)“…Depression and anxiety are prevalent in patients with idiopathic pulmonary fibrosis (IPF). Recent researchers reveal that intermittent hypoxia (IH) increases…”
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Swimming exercise reverses chronic unpredictable mild stress–induced depression-like behaviors and alleviates neuroinflammation and collapsing response mediator protein-2–mediated neuroplasticity injury in adult male mice
Published in Neuroreport (06-04-2022)“…Impaired neuroplasticity and neuroinflammation are vital in the mechanisms of depression. Exercise alleviates depressive symptoms and ameliorates body…”
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Resilience in the LPS-induced acute depressive-like behaviors: Increase of CRMP2 neuroprotection and microtubule dynamics in hippocampus
Published in Brain research bulletin (01-09-2020)“…•Resilience in the LPS-induced acute depressive-like behaviors was firstly confirmed.•LPS induced acute depressive-like behaviors in rats.•CRMP2…”
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Maternal deprivation induces cytoskeletal alterations and depressive-like behavior in adult male rats by regulating the AKT/GSK3β/CRMP2 signaling pathway
Published in Physiology & behavior (01-12-2021)“…•Adult male rats with maternal deprivation experience show depressive-like behaviors.•Brief maternal separation does not alter the behavioral performance of…”
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14
Neuroinflammation decreased hippocampal microtubule dynamics in the acute behavioral deficits induced by intracerebroventricular injection of lipopolysaccharide in male adult rats
Published in Neuroreport (05-05-2021)“…Neuroinflammation plays a vital role in the pathology of depression. Microtubule dynamics produces an immediate response to stress, but the effect of…”
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15
Brief pup separation during lactation confers resilience in behavioural deficits induced by chronic restraint stress in postpartum C57BL/6J dams
Published in Journal of psychiatry & neuroscience (01-05-2023)“…The postpartum period is a complex time for females that affects health recovery. Stress during this period is one of the main risk factors for depression…”
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16
Maternal separation during lactation affects recognition memory, emotional behaviors, hippocampus and gut microbiota composition in C57BL6J adolescent female mice
Published in Behavioural brain research (05-01-2025)“…Maternal separation (MS) in rodents is a paradigm of early life events that affects neurological development in depression. Adolescence is a time of dramatic…”
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Swimming exercise reduces the vulnerability to stress and contributes to the AKT/GSK3β/CRMP2 pathway and microtubule dynamics mediated protective effects on neuroplasticity in male C57BL/6 mice
Published in Pharmacology, biochemistry and behavior (01-12-2021)“…While swimming exercise has been shown to positively affect the development of the nervous system, it still remains unclear whether it reduces the…”
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18
Neuroinflammation decreased hippocampal microtubule dynamics in the acute behavioral deficits induced by intracerebroventricular injection of lipopolysaccharide in male adult rats
Published in Neuroreport (12-04-2021)“…Neuroinflammation plays a vital role in the pathology of depression. Microtubule dynamics produces an immediate response to stress, but the effect of…”
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19
Fluoxetine exposure for more than 2 days decreases the neuronal plasticity mediated by CRMP2 in differentiated PC12 cells
Published in Brain research bulletin (01-05-2020)“…•FLU exposure increased neuronal plasticity at day 1.•FLU exposure for longer periods has an opposite effect on the regulation of neuronal plasticity at day 1…”
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20
Swimming Exercise Modulates Gut Microbiota in CUMS-Induced Depressed Mice
Published in Neuropsychiatric disease and treatment (31-05-2022)“…Gut microbiota is associated with anxiety and depression, while exercise has been proved to alleviate depressive symptoms. However, the interaction of…”
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