Search Results - "Wu, Zhengming"

Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity by Zhu, Huang, Blum, Robert H., Bernareggi, Davide, Ask, Eivind Heggernes, Wu, Zhengming, Hoel, Hanna Julie, Meng, Zhipeng, Wu, Chengsheng, Guan, Kun-Liang, Malmberg, Karl-Johan, Kaufman, Dan S.

“…Cytokine-inducible SH2-containing protein (CIS; encoded by the gene CISH) is a key negative regulator of interleukin-15 (IL-15) signaling in natural killer…”
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OGT regulated O-GlcNAcylation promotes papillary thyroid cancer malignancy via activating YAP by Li, Xiaoyan, Wu, Zhengming, He, Jing, Jin, Yiting, Chu, Chengyu, Cao, Yun, Gu, Fei, Wang, Hongying, Hou, Chenjian, Liu, Xiuping, Zou, Qiang

“…The incidence of thyroid cancer is growing rapidly during the past decades worldwide. Although most thyroid tumors are curable, some patients diagnosed with…”
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TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells by Wu, ZhengMing, Wei, Dong, Gao, WenChao, Xu, YuTing, Hu, ZhiQian, Ma, ZhenYu, Gao, ChunFang, Zhu, XiaoYan, Li, QingQuan

“…Liver metastasis is a leading cause of death in patients with colorectal cancer. We previously found that colorectal cancer tumor-initiating cells (TICs)…”
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YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis by Wu, Zhengming, Su, Junhui, Li, Fu-long, Chen, Tao, Mayner, Jaimie, Engler, Adam, Ma, Shenghong, Li, Qingquan, Guan, Kun-Liang

“…Small cell lung cancer (SCLC) is highly lethal due to its prevalent metastasis. Most SCLCs have inactivating mutations in TP53 and RB1 . We find that loss of…”
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Targeting a Sirt5-Positive Subpopulation Overcomes Multidrug Resistance in Wild-Type Kras Colorectal Carcinomas by Du, ZunGuo, Liu, XiuJuan, Chen, Tao, Gao, WenChao, Wu, ZhengMing, Hu, ZhiQian, Wei, Dong, Gao, ChunFang, Li, QingQuan

“…A major obstacle for successful management of patients with colorectal carcinoma (CRC) is resistance to anti-cancer cytotoxic treatments. Here, we identified a…”
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Combined HASPIN and mTOR inhibition is synergistic against KRAS-driven carcinomas by Xu, Chenyue, Gao, Qiongmei, Wu, Zhengming, Lou, Weijuan, Li, Xiaoyan, Wang, Menghui, Wang, Nianhong, Li, Qingquan

“…•Combined inhibition of HASPIN and mTOR has a synergistic inhibitory effect on the proliferation of KRAS-mutant tumor cells.•In a xenograft tumor model of…”
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Solubility Model of Solid Solute in Supercritical Fluid Solvent Based on UNIFAC by Zhao, Yueqiang, Liu, Weiwei, Wu, Zhengming

“…A semitheoretical model based on UNIFAC was proposed to correlate the solubility of solid solute in supercritical fluid (SF) solvent simply and reliably, which…”
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Insights into recent findings and clinical application of YAP and TAZ in cancer by Franklin, J. Matthew, Wu, Zhengming, Guan, Kun-Liang

“…Decades of research have mapped out the basic mechanics of the Hippo pathway. The paralogues Yes-associated protein (YAP) and transcriptional co-activator with…”
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Acetyl-CoA, protein acetylation, and liver cancer by Wu, Zhengming, Guan, Kun-Liang

“…Using multi-omics approaches, Park et al. (2022) show that reduced cellular acetyl-CoA and protein hypoacetylation promote liver cancer growth and…”
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Hippo Signaling in Embryogenesis and Development by Wu, Zhengming, Guan, Kun-Liang

“…Hippo pathway components are structurally and functionally conserved and are notable for their role in controlling organ size. More diverse functions of the…”
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Hippo signalling maintains ER expression and ER+ breast cancer growth by Ma, Shenghong, Wu, Zhengming, Yang, Feng, Zhang, Jianmin, Johnson, Randy L., Rosenfeld, Michael G., Guan, Kun-Liang

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Oxygen-assisted Cathodic Deposition of Copper-Carboxylate Metal–Organic Framework Films by Xiao, Yushuang, Wu, Zhengming, Zhang, Qing, Li, Pingping, Yu, Huijun, Lu, Guang

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Deletion of CISH in Human Pluripotent Stem Cell-Derived Natural Killer Cells Enhances Anti-Tumor Activity Via Metabolic Reprogramming by Zhu, Huang, Blum, Robert, Wu, Zhengming, Meng, Zhipeng, Guan, Kun-Liang, Kaufman, Dan S

“…Cellular metabolism is now recognized to play a key role in regulating function and differentiation of immune cells. Immune cells undergo dynamic metabolic…”
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Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides by Li, Fu-Long, Fu, Vivian, Liu, Guangbo, Tang, Tracy, Konradi, Andrei W., Peng, Xiao, Kemper, Esther, Cravatt, Benjamin F., Franklin, J. Matthew, Wu, Zhengming, Mayfield, Joshua, Dixon, Jack E., Gerwick, William H., Guan, Kun-Liang

“…The Hippo pathway plays a key role in development, organ size control and tissue homeostasis, and its dysregulation contributes to cancer. The LATS tumor…”
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Towards Human-Compatible Autonomous Car: A Study of Non-Verbal Turing Test in Automated Driving With Affective Transition Modelling by Li, Zhaoning, Jiang, Qiaoli, Wu, Zhengming, Liu, Anqi, Wu, Haiyan, Huang, Miner, Huang, Kai, Ku, Yixuan

“…Autonomous cars are indispensable when humans go further down the hands-free route. Although existing literature highlights that the acceptance of the…”
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Oxygen‐Assisted Cathodic Deposition of Zeolitic Imidazolate Frameworks with Controlled Thickness by Zhang, Qing, Wu, Zhengming, Lv, Yuan, Li, Yali, Zhao, Yajing, Zhang, Rui, Xiao, Yushuang, Shi, Xiaofei, Zhang, Danrui, Hua, Rui, Yao, Jianlin, Guo, Jun, Huang, Rong, Cui, Yi, Kang, Zhenhui, Goswami, Subhadip, Robison, Lee, Song, Kepeng, Li, Xinghua, Han, Yu, Chi, Lifeng, Farha, Omar K., Lu, Guang

“…Processing metal–organic frameworks (MOFs) as films with controllable thickness on a substrate is increasingly crucial for many applications to realize…”
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ZnO@ZIF Core-Shell Single Crystals Formed by in Situ Conversion of ZnO Particles by Sun, Ying, Zhang, Qing, Xu, Xiaona, Zhang, Lin, Wu, Zhengming, Guo, Jun, Lu, Guang

“…We herein report the formation of two types of ZnO@ZIF core–shell single crystals through the in situ conversion of ZnO particles. The hybrid core–shell single…”
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Hippo signalling maintains ER expression and ER breast cancer growth/Reply by Ma, Shenghong, Wu, Zhengming, Yang, Feng, Zhang, Jianmin, Johnson, Randy L, Rosenfeld, Michael G, Guan, Kun-Liang, Britschgi, Adrian, Couto, Joana Pinto, Bentires-Alj, Mohamed

“…By gene ontology enrichment analysis of the differentially expressed genes, we found an enrichment in the signatures for YAP target genes, as well as apoptosis…”
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Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB by Li, Fu‐Long, Wu, Zhengming, Gao, Yong‐Qi, Bowling, Forrest Z, Franklin, J Matthew, Hu, Chongze, Suhandynata, Raymond T, Frohman, Michael A, Airola, Michael V, Zhou, Huilin, Guan, Kun‐Liang

“…The Arf GTPase family is involved in a wide range of cellular regulation including membrane trafficking and organelle–structure assembly. Here, we have…”
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Statistical mechanical theory of fluid mixtures by Zhao, Yueqiang, Wu, Zhengming, Liu, Weiwei

“…A general statistical mechanical theory of fluid mixtures (liquid mixtures and gas mixtures) is developed based on the statistical mechanical expression of…”
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