Search Results - "Wu, Yuxuan"
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Ethical Considerations of Using ChatGPT in Health Care
Published in Journal of medical Internet research (11-08-2023)“…ChatGPT has promising applications in health care, but potential ethical issues need to be addressed proactively to prevent harm. ChatGPT presents potential…”
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Therapeutic base editing of human hematopoietic stem cells
Published in Nature medicine (01-04-2020)“…Base editing by nucleotide deaminases linked to programmable DNA-binding proteins represents a promising approach to permanently remedy blood disorders,…”
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3
Dual base editor catalyzes both cytosine and adenine base conversions in human cells
Published in Nature biotechnology (01-07-2020)“…Although base editors are useful tools for precise genome editing, current base editors can only convert either adenines or cytosines. We developed a dual…”
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Solid surface frustrated Lewis pair constructed on layered AlOOH for hydrogenation reaction
Published in Nature communications (28-04-2022)“…Designing heterogeneous solid surface frustrated Lewis pair (ssFLP) catalyst for hydrogenation is a new challenge in catalysis and no research has been…”
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Highly efficient therapeutic gene editing of human hematopoietic stem cells
Published in Nature medicine (01-05-2019)“…Re-expression of the paralogous γ-globin genes ( HBG1/2 ) could be a universal strategy to ameliorate the severe β-globin disorders sickle cell disease (SCD)…”
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A novel high-strength poly(ionic liquid)/PVA hydrogel dressing for antibacterial applications
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (01-06-2019)“…[Display omitted] •The poly(ionic liquid)/PVA hydrogel dressing does not release antibacterial agents.•This hydrogel dressing exhibits effective antibacterial…”
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Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9
Published in Cell stem cell (05-12-2013)“…The CRISPR-Cas9 system has been employed to generate mutant alleles in a range of different organisms. However, so far there have not been reports of use of…”
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Clinicopathological variables influencing overall survival, recurrence and post-recurrence survival in resected stage I non-small-cell lung cancer
Published in BMC cancer (24-02-2020)“…To investigate clinicopathological variables influencing overall survival, overall recurrence, and post-recurrence survival (PRS) in patients who experienced…”
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Trajectory-based characteristic analysis and decision modeling of the lane-changing process in intertunnel weaving sections
Published in PloS one (04-04-2022)“…Existing lane-changing models generally neglect the detailed modeling of lane-changing actions and model lane-changing only as an instantaneous event. In this…”
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Risk factors for mortality among lung cancer patients with covid-19 infection: A systematic review and meta-analysis
Published in PloS one (08-09-2023)“…Background Lung cancer patients with coronavirus disease 2019 (COVID-19) infection experience high mortality rates. The study aims to determine the risk…”
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Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain
Published in Nature cell biology (01-06-2020)“…Cytidine base editors are powerful genetic tools that catalyse cytidine to thymidine conversion at specific genomic loci, and further improvement of the…”
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MILE: Memory-Interactive Learning Engine for Neuro-Symbolic Solutions to Mathematical Problems
Published in IEEE access (2024)“…Mathematical problem solving is a task that examines the capacity of machine learning systems to perform quantitative and logical reasoning. Existing work…”
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Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells
Published in Cell research (01-01-2015)“…Spermatogonial stem cells (SSCs) can produce numerous male gametes after transplantation into recipient testes, presenting a valuable approach for gene therapy…”
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14
Three-Dimensional Reconstruction Method of Rapeseed Plants in the Whole Growth Period Using RGB-D Camera
Published in Sensors (Basel, Switzerland) (06-07-2021)“…The three-dimensional reconstruction method using RGB-D camera has a good balance in hardware cost and point cloud quality. However, due to the limitation of…”
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Evaluating significance of European-associated index SNPs in the East Asian population for 31 complex phenotypes
Published in BMC genomics (13-06-2023)“…Genome-wide association studies (GWASs) have identified many single-nucleotide polymorphisms (SNPs) associated with complex phenotypes in the European (EUR)…”
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Genesis mechanism and Mg isotope difference between the Sinian and Cambrian dolomites in Tarim Basin
Published in Science China. Earth sciences (01-02-2023)“…Dolomite genesis is a century-old mystery in sedimentology. To reveal the mechanism of dolomite genesis, two core problems need to be addressed. The first is…”
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Therapeutic adenine base editing of human hematopoietic stem cells
Published in Nature communications (13-01-2023)“…In β-thalassemia, either γ-globin induction to form fetal hemoglobin (α2γ2) or β-globin repair to restore adult hemoglobin (α2β2) could be therapeutic. ABE8e,…”
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Detecting associated genes for complex traits shared across East Asian and European populations under the framework of composite null hypothesis testing
Published in Journal of translational medicine (23-09-2022)“…Abstract Background Detecting trans-ethnic common associated genetic loci can offer important insights into shared genetic components underlying complex…”
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Techno-economic feasibility analysis of optimally sized a biomass/PV/DG hybrid system under different operation modes in the remote area
Published in Sustainable energy technologies and assessments (01-08-2022)“…•A photovoltaic/biomass generator/diesel generator hybrid energy system for remote areas.•Comparison of hybrid energy system under different system design is…”
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Conservative behavior of Mg isotopes in dolomite during diagenesis and hydrothermal alteration: A case study in the Lower Cambrian Qiulitage Formation, Gucheng area, Tarim Basin
Published in Applied geochemistry (01-01-2023)“…Recovering the Mg isotopic composition of seawater using penecontemporaneous dolomite is possible; however, the Mg isotopic composition of dolomite may be…”
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