Search Results - "Wu, Yue‐E"

Machine Learning: A New Approach for Dose Individualization by Li, Qiu‐Yue, Tang, Bo‐Hao, Wu, Yue‐E, Yao, Bu‐Fan, Zhang, Wei, Zheng, Yi, Zhou, Yue, Anker, John, Hao, Guo‐Xiang, Zhao, Wei

“…The application of machine learning (ML) has shown promising results in precision medicine due to its exceptional performance in dealing with complex…”
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Prognostic value of infarct-related-lead Tpeak–Tend/QT ratio in patients with ST-segment elevation myocardial infarction by Wu, Yue-e, Ma, Lan, Hu, Ze-ping

“…Tpeak–Tend/QT ratio (Tp–e/QT) in patients with ST-segment elevation myocardial infarction (STEMI) is reportedly associated with major adverse cardiac events…”
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Population pharmacokinetics and dose optimization of levofloxacin in elderly patients with pneumonia by He, Yun‐Ying, Sun, Jing, Wu, Yue‐E, Wang, Yong‐Bin, Anker, John, Hao, Guo‐Xiang, Sun, De‐Qing, Zhao, Wei

“…Aims Levofloxacin is a quinolone antibiotic with a broad antibacterial spectrum. It is frequently used in elderly patients with pneumonia. The pharmacokinetic…”
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Use of Machine Learning for Dosage Individualization of Vancomycin in Neonates by Tang, Bo-Hao, Zhang, Jin-Yuan, Allegaert, Karel, Hao, Guo-Xiang, Yao, Bu-Fan, Leroux, Stephanie, Thomson, Alison H., Yu, Ze, Gao, Fei, Zheng, Yi, Zhou, Yue, Capparelli, Edmund V., Biran, Valerie, Simon, Nicolas, Meibohm, Bernd, Lo, Yoke-Lin, Marques, Remedios, Peris, Jose-Esteban, Lutsar, Irja, Saito, Jumpei, Jacqz-Aigrain, Evelyne, van den Anker, John, Wu, Yue-E., Zhao, Wei

“…Background and Objective High variability in vancomycin exposure in neonates requires advanced individualized dosing regimens. Achieving steady-state trough…”
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Population pharmacokinetics and dosing optimization of mezlocillin in neonates and young infants by Zhou, Jing, Jiang, Li, Zhang, Zhi Ling, Wang, Zhao Rui, Zhang, Yan Xiu, Lin, Xu, Tang, Bo Hao, Yao, Bu Fan, Guo, Zi Xuan, Yang, Jing Jing, Van Den Anker, John, Wu, Yue E, Zhao, Wei

“…Abstract Objectives Mezlocillin is used in the treatment of neonatal infectious diseases. However, due to the absence of population pharmacokinetic studies in…”
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Developmental population pharmacokinetics of caffeine in Chinese premature infants with apnoea of prematurity: A post‐marketing study to support paediatric labelling in China by Gao, Xiang‐Bo, Zheng, Yi, Yang, Fan, Wang, Chen‐Hong, Jiang, Zhou‐Hong, Wu, Yue‐E, Jacqz‐Aigrain, Evelyne, Ni, Shao‐Qing, Zhao, Wei

“…Aims The aim of the study was to evaluate the suitability of the current caffeine dosing regimen for the Chinese population using modelling and simulation…”
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Drug Clearance in Neonates: A Combination of Population Pharmacokinetic Modelling and Machine Learning Approaches to Improve Individual Prediction by Tang, Bo-Hao, Guan, Zheng, Allegaert, Karel, Wu, Yue-E., Manolis, Efthymios, Leroux, Stephanie, Yao, Bu-Fan, Shi, Hai-Yan, Li, Xiao, Huang, Xin, Wang, Wen-Qi, Shen, A.-Dong, Wang, Xiao-Ling, Wang, Tian-You, Kou, Chen, Xu, Hai-Yan, Zhou, Yue, Zheng, Yi, Hao, Guo-Xiang, Xu, Bao-Ping, Thomson, Alison H., Capparelli, Edmund V., Biran, Valerie, Simon, Nicolas, Meibohm, Bernd, Lo, Yoke-Lin, Marques, Remedios, Peris, Jose-Esteban, Lutsar, Irja, Saito, Jumpei, Burggraaf, Jacobus, Jacqz-Aigrain, Evelyne, van den Anker, John, Zhao, Wei

“…Background Population pharmacokinetic evaluations have been widely used in neonatal pharmacokinetic studies, while machine learning has become a popular…”
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Clinical utility of a model‐based amoxicillin dosage regimen in neonates with early‐onset sepsis by Kou, Chen, Li, Di‐Fei, Tang, Bo‐Hao, Dong, Lei, Yao, Bu‐Fan, Anker, John, You, Dian‐Ping, Wu, Yue‐E, Zhao, Wei

“…Early‐onset sepsis (EOS) is one of the most significant causes of morbidity and mortality in neonates. Currently, amoxicillin is empirically used to treat…”
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Epithelial lining fluid concentrations of ceftriaxone in children with community‐acquired pneumonia by Dong, Yi‐Ning, Wang, Ya‐Kun, Li, Qian, Tang, Bo‐Hao, Anker, John, Hao, Guo‐Xiang, Zheng, Yi, Tian, Li‐Yuan, You, Dian‐Ping, Wu, Yue‐E, Zhao, Wei

“…Ceftriaxone is widely used in children with community‐acquired pneumonia. Currently, there are no available data regarding epithelial lining fluid (ELF)…”
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Relationship Between Linezolid Exposure and the Typical Clinical Laboratory Safety and Bacterial Clearance in Chinese Pediatric Patients by Huo, Ben-Nian, Wu, Yue-E., Shu, Ling, Zhang, Ruo-Qi, Xiao, Jian-Wen, Li, Qian-Bo, Zhao, Wei, Jia, Yun-Tao, Song, Lin

“…Objectives: There have been limited studies concerning the safety and efficacy of linezolid (LZD) in children. This study aimed to evaluate the association…”
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Editorial: Model-Based Evaluation of Antimicrobial Agents in Children by Zhao, Wei, Wu, Yue-E, van den Anker, John

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Optimal dose of cefotaxime in neonates with early-onset sepsis: A developmental pharmacokinetic model-based evaluation by Shang, Zhen-Hai, Wu, Yue-E, Lv, Dong-Mei, Zhang, Wei, Liu, Wen-Qiang, van den Anker, John, Xu, Yan, Zhao, Wei

“…Objective: The perspective of real-world study is especially relevant to newborns, enabling dosage regimen optimization and regulatory approval of medications…”
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Clinical utiliy of a model‐based piperacillin dose in neonates with early‐onset sepsis by Wu, Yue‐E, Hou, Shan‐Shan, Fang, Zeng‐Yu, Tang, Bo‐Hao, Yao, Bu‐Fan, Dong, Yi‐Ning, Li, Xue, Shi, Hai‐Yan, Zheng, Yi, Hao, Guo‐Xiang, Huang, Xin, Van Den Anker, John, Yu, Yong‐Hui, Zhao, Wei

“…Aims Early‐onset sepsis (EOS) is a common disease in neonates with a high morbidity and mortality rate. Piperacillin/tazobactam has been used extensively and…”
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Population Pharmacokinetics and Dosing Optimization of Amoxicillin in Chinese Infants by Wu, Yue‐E, Wang, Ya‐Kun, Tang, Bo‐Hao, Dong, Lei, Li, Xue, Zhang, Wei, Li, Di‐Fei, Tian, Li‐Yuan, den Anker, John, You, Dian‐Ping, Zhao, Wei

“…Amoxicillin is used to treat various bacterial infections (eg, pneumonia, sepsis, meningitis) in infants. Despite its frequent use, there is a lack of…”
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Population pharmacokinetics-pharmacodynamics of ceftazidime in neonates and young infants: Dosing optimization for neonatal sepsis by Li, Xue, Qi, Hui, Jin, Fei, Yao, Bu-Fan, Wu, Yue-E, Qi, Yu-Jie, Kou, Chen, Wu, Xi-Rong, Luo, Xiao-Jing, Shen, Yan-Hua, Zheng, Xu, Wang, Yong-Hong, Xu, Fang, Jiao, Wei-Wei, Li, Jie-Qiong, Xiao, Jing, Dong, Yi-Ning, Du, Bin, Shi, Hai-Yan, Xu, Bao-Ping, Shen, A-Dong, Zhao, Wei

“…Ceftazidime is a third-generation cephalosporin with high activity against many pathogens. But the ambiguity and diversity of the dosing regimens in neonates…”
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Systematic review of efficacy, safety and pharmacokinetics of intravenous and intraventricular vancomycin for central nervous system infections by Liu, Shu-Ping, Xiao, Jing, Liu, Ya-Li, Wu, Yue-E, Qi, Hui, Wang, Zhuang-Zhuang, Shen, A-Dong, Liu, Gang, Zhao, Wei

“…The decision of vancomycin dosage for central nervous system (CNS) infections is still a challenge because its bactericidal nature in cerebrospinal fluid (CSF)…”
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Developmental Population Pharmacokinetics and Dosing Optimization of Cefepime in Neonates and Young Infants by Zhao, Yang, Yao, Bu-Fan, Kou, Chen, Xu, Hai-Yan, Tang, Bo-Hao, Wu, Yue-E, Hao, Guo-Xiang, Zhang, Xin-Ping, Zhao, Wei

“…Cefepime is used to treat severe infections in neonates. Pharmacokinetic data have only been evaluated among preterm neonates and population pharmacokinetic…”
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Carbapenem-Resistant Enterobacteriaceae Bloodstream Infection Treated Successfully With High-Dose Meropenem in a Preterm Neonate by Wu, Yue-E, Xu, Hai-Yan, Shi, Hai-Yan, van den Anker, John, Chen, Xiao-Yu, Zhao, Wei

“…Carbapenem-resistant enterobacteriaceae (CRE) bloodstream infections have been rapidly spreading worldwide with a high mortality and pose a challenge to…”
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Meropenem for children with severe pneumonia: Protocol for a randomized controlled trial by Tian, Xue, Dong, Lei, Jiang, Ting-Ting, Tang, Bo-Hao, Wang, Ze-Ming, Wu, Yue-E, You, Dian-Ping, Bi, Jing, Qian, Su-Yun, Qi, Hui, Shen, A-Dong

“…Background: Pneumonia, caused by infection or other factors, seriously endangers the health of children. Meropenem is an effective broad-spectrum antibiotic…”
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Developmental Pharmacogenetics of CYP2D6 in Chinese Children: Loratadine as a Substrate Drug by Li, Qian, Wu, Yue-E, Wang, Kai, Shi, Hai-Yan, Zhou, Yue, Zheng, Yi, Hao, Guo-Xiang, Yang, Yi-Lei, Su, Le-Qun, Wang, Wen-Qi, Yang, Xin-Mei, Zhao, Wei

“…Objective: The elucidation of CYP2D6 developmental pharmacogenetics in children has improved, however, these findings have been largely limited to studies of…”
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