Search Results - "Wu, Yixing"

Deciphering the molecular regulatory of RAB32/GPRC5A axis in chronic obstructive pulmonary disease by Wu, Yixing, He, Binfeng, Hua, Jianlan, Hu, Weiping, Han, Yaopin, Zhang, Jing

“…Chronic obstructive pulmonary disease (COPD) is a significant public health problem characterized by persistent airflow limitation. Despite previous research…”
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Comparisons between In-Check DIAL® and PF810® in evaluation and training inspiratory capacity for using dry powder inhalers by Wu, Yixing, Li, Li, Gong, Ying, Li, Xingjing, Ye, Xiaofen, Zhang, Jing

“…Dry powder inhalers (DPIs) rely on both internal resistance and patients' inspiratory capacity for effective operation. Optimal inspiratory technique is…”
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The antioxidant protein Oxr1 influences aspects of mitochondrial morphology by Wu, Yixing, Davies, Kay E., Oliver, Peter L.

“…Oxidative stress (OS) and mitochondrial dysfunction are implicated in neurodegenerative disease, suggesting that antioxidant defence systems are critical for…”
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Editorial: New insights into the role of neuroinflammation and glial cells in the development of neurological disorders by Pérez-González, Marta, Solas, Maite, Wu, Yixing, Mela, Virginia

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The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model by Wu, Yixing, Whittaker, Heather T, Noy, Suzanna, Cleverley, Karen, Brault, Veronique, Herault, Yann, Fisher, Elizabeth M C, Wiseman, Frances K

“…People with Down syndrome (DS), caused by trisomy of chromosome 21 have a greatly increased risk of developing Alzheimer's disease (AD). This is in part…”
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A Wars2 Mutant Mouse Model Displays OXPHOS Deficiencies and Activation of Tissue-Specific Stress Response Pathways by Agnew, Thomas, Goldsworthy, Michelle, Aguilar, Carlos, Morgan, Anna, Simon, Michelle, Hilton, Helen, Esapa, Chris, Wu, Yixing, Cater, Heather, Bentley, Liz, Scudamore, Cheryl, Poulton, Joanna, Morten, Karl J., Thompson, Kyle, He, Langping, Brown, Steve D.M., Taylor, Robert W., Bowl, Michael R., Cox, Roger D.

“…Mutations in genes essential for mitochondrial function have pleiotropic effects. The mechanisms underlying these traits yield insights into metabolic…”
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High lead exposure is associated with telomere length shortening in Chinese battery manufacturing plant workers by Wu, Yixing, Liu, Yimin, Ni, Na, Bao, Bei, Zhang, Cheng, Lu, Lingeng

“…ObjectivesCritically shortening of telomere length caused by various factors including environmental pollutants results in genome instability and…”
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Next‐generation spatial transcriptomics: unleashing the power to gear up translational oncology by Wang, Nan, Hong, Weifeng, Wu, Yixing, Chen, Zhe‐Sheng, Bai, Minghua, Wang, Weixin, Zhu, Ji

“…The growing advances in spatial transcriptomics (ST) stand as the new frontier bringing unprecedented influences in the realm of translational oncology. This…”
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Role of RhoB in the Regulation of Pulmonary Endothelial and Smooth Muscle Cell Responses to Hypoxia by Wojciak-Stothard, Beata, Zhao, Lan, Oliver, Eduardo, Dubois, Olivier, Wu, Yixing, Kardassis, Dimitris, Vasilaki, Eleftheria, Huang, Minzhou, Mitchell, Jane A, Harrington, Louise S, Prendergast, George C, Wilkins, Martin R

“…RATIONALE:RhoA and Rho kinase contribute to pulmonary vasoconstriction and vascular remodeling in pulmonary hypertension. RhoB, a protein homologous to RhoA…”
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Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis by Wu, Yixing, Bai, Ying, McEwan, David G, Bentley, Liz, Aravani, Dimitra, Cox, Roger D

“…The small GTPase ARF family member ARL15 gene locus is associated in population studies with increased risk of type 2 diabetes, lower adiponectin and higher…”
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Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B by Wu, Yixing, Mumford, Paige, Noy, Suzanna, Cleverley, Karen, Mrzyglod, Alicja, Luo, Dinghao, van Dalen, Floris, Verdoes, Martijn, Fisher, Elizabeth M C, Wiseman, Frances K

“…Cathepsin B is a cysteine protease that is implicated in multiple aspects of Alzheimer's disease pathogenesis. The endogenous inhibitor of this enzyme,…”
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Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II by Lu, Lingeng, Katsaros, Dionyssios, Shaverdashvili, Khvaramze, Qian, Biyun, Wu, Yixing, de la Longrais, Irene A. Rigault, Preti, Mario, Menato, Guido, Yu, Herbert

“…Abstract Lin-28 and lin-28B are RNA-binding proteins which can block microRNA let-7 maturation and affect the differentiation and proliferation of embryonic…”
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Standardized inhalation capability assessment: A key to optimal inhaler selection for inhalation therapy by Wu, Yixing, Zhang, Jing

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First person – Yixing Wu and Ying Bai

“…ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers…”
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MP30-14 ENHANCED CT RADIOMICS PREDICTION OF CLEAR CELL RENAL CELL CARCINOMA PD-L1 EXPRESSION WITH ADAPTIVE FEATURE ENGINEERING STRATEGIES by Wu, Yixing, Shieh, Alexander, Jogi, Pawan, Cen, Steven, Wallace, William Dean, Kuo, Jay, Duddalwar, Vinay

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In vitro culture and oxygen consumption of NSCs in size-controlled neurospheres of Ca-alginate/gelatin microbead by Song, Kedong, Yang, Yanfei, Li, Shixiao, Wu, Meiling, Wu, Yixing, Lim, Mayasari, Liu, Tianqing

“…Neural stem cells (NSCs) forming neurospheres in a conventional culture tend to develop necrotic/apoptotic centers due to mass transport limitations. In this…”
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Syndecan-1 and KRAS Gene Expression Signature Associates With Patient Survival in Pancreatic Cancer by Wu, Yixing, Huang, Huatian, Fervers, Beatrice, Lu, Lingeng

“…The purpose of this study was to investigate the association of syndecan-1 (SDC1) and KRAS molecular characteristics with patient survival in pancreatic…”
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Investigating how CSTB affects the activity of cysteine cathepsin in the AD‐DS, EOAD, and human cellular models of trisomy Hsa21 by Wu, Yixing, Cleverley, Karen, van Dalen, Floris, Verdoes, Martijn, Crawford, Samuel, Wray, Selina, Wiseman, Frances K

“…Background People with Down syndrome (DS) have a high genetic risk of developing Alzheimer’s disease (AD) ‐related dementia and pathology. Triplication of a…”
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Extracorporeal Closed-Loop Respiratory Regulation for Patients With Respiratory Difficulty Using a Soft Bionic Robot by Zhang, Yan, Ge, Qinggang, Wang, Zongyu, Qin, Yuxing, Wu, Yixing, Wang, Mingjing, Shi, Mai, Xue, Lei, Guo, Weidong, Zhang, Yuru, Wang, Guangyu, Wang, Dangxiao

“…Objective: Respiratory regulation is critical for patients with respiratory dysfunction. Clinically used ventilators can lead to long-term dependence and…”
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The effects of Cstb duplication on APP/amyloid-[beta] pathology and cathepsin B activity in a mouse model by Wu, Yixing, Whittaker, Heather T, Noy, Suzanna, Cleverley, Karen, Brault, Veronique, Herault, Yann, Fisher, Elizabeth M. C, Wiseman, Frances K

“…People with Down syndrome (DS), caused by trisomy of chromosome 21 have a greatly increased risk of developing Alzheimer's disease (AD). This is in part…”
Get full text