Search Results - "Wu, Yinrong"

Small molecule-based immunomodulators for cancer therapy by Wu, Yinrong, Yang, Zichao, Cheng, Kui, Bi, Huichang, Chen, Jianjun

“…Immunotherapy has led to a paradigm shift in the treatment of cancer. Current cancer immunotherapies are mostly antibody-based, thus possessing advantages in…”
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Copper-Mediated Decarboxylative Coupling of 3-Indoleacetic Acids with Pyrazolones by Wen, Kangmei, Wu, Yinrong, Chen, Jiewen, Shi, Jie, Zheng, Mulin, Yao, Xingang, Tang, Xiaodong

“…A copper-mediated decarboxylative coupling reaction of 3-indoleacetic acids with pyrazolones was described. This protocol realized new functionalization of…”
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Toward establishing a rapid constant temperature detection method for canine parvovirus based on endonuclease activities by Weng, Shaoting, Ma, Shengming, Xing, Yueteng, Zhang, Wenhui, Wu, Yinrong, Fu, Mengyao, Luo, Zhongyi, Li, Qiuying, Lin, Sen, Zhang, Longfei, Wang, Yao

“…Canine parvovirus (CPV) can cause high morbidity and mortality rates in puppies, posing a significant threat to both pet dogs and the breeding industry. Rapid,…”
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Copper-Mediated Decarboxylative Sulfonylation of Arylacetic Acids with Sodium Sulfinates by Wu, Yinrong, Chen, Jiewen, Li, Lu, Wen, Kangmei, Yao, Xingang, Pang, Jianxin, Wu, Ting, Tang, Xiaodong

“…Herein, we present a copper-mediated decarboxylative sulfonylation of arylacetic acids with sodium sulfinates that provides viable access to sulfone compounds…”
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Efficient sulfonylation of ketones with sodium sulfinates for the synthesis of β-keto sulfones by Deng, Siqi, Liang, En, Wu, Yinrong, Tang, Xiaodong

“…[Display omitted] •Direct formation of β-keto sulfones.•Dimethyl sulfoxide (DMSO) serves as green oxidant.•Available starting materials, good functional group…”
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Copper-Mediated Decarboxylative Coupling between Arylacetic Acids and 1,3-Dicarbonyl Compounds by Wu, Yinrong, Wen, Kangmei, Chen, Jiewen, Shi, Jie, Yao, Xingang, Tang, Xiaodong

“…A copper-mediated decarboxylative coupling reaction between arylacetic acids and 1,3-dicarbonyl compounds was described. Significantly,…”
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α‐Benzylation of Carbonyl Compounds Enabled by Synergistic Copper/Amine Catalyzed Decarboxylation of Arylacetic Acids by Wen, Kangmei, Feng, Mengxia, Gao, Qiwen, Chen, Chen, Wu, Yinrong, Zhou, Jiamin, Huang, Liangbin, Tang, Xiaodong

“…Herein, we report synergistic copper/amine‐catalyzed reactions for directly α‐benzylating carbonyl compounds with arylacetic acids. These reactions represent…”
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Transition Metal Catalyst-Free C‑3 Sulfonylmethylation of Imidazo[1,2‑a]pyridines with Glyoxylic Acid and Sodium Sulfinates in Water by Chen, Jiewen, Wen, Kangmei, Wu, Yinrong, Shi, Jie, Yao, Xingang, Tang, Xiaodong

“…Herein, we describe an efficient and benign protocol for direct C-3 sulfonylmethylation of imidazo­[1,2-a]­pyridines with glyoxylic acid and sodium sulfinates…”
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Copper-Catalyzed C‑3 Functionalization of Imidazo[1,2‑a]pyridines with 3‑Indoleacetic Acids by Wu, Yinrong, Li, Lu, Wen, Kangmei, Deng, Jie, Chen, Jiewen, Shi, Jie, Wu, Ting, Pang, Jianxin, Tang, Xiaodong

“…A copper-catalyzed C-3 functionalization of imidazo­[1,2-a]­pyridines with 3-indoleacetic acids through an aerobic oxidative decarboxylative process has been…”
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Copper-catalyzed aerobic oxidative cyclization protocol for the synthesis of quinazolines via amination of C(sp3)-H bonds of methylazaarenes by Liang, En, Wu, Yinrong, Chen, Jiewen, Xiong, Wei, Zhao, Jinwu, Yao, Xingang, Tang, Xiaodong

“…A new aerobic copper-catalyzed three-component synthesis of azaaryl-substituted quinazolines has been developed, which featured inexpensive methylazaarenes as…”
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Discovery of KRas G12C-IN-3 and Pomalidomide-based PROTACs as degraders of endogenous KRAS G12C with potent anticancer activity by Li, Ling, Wu, Yinrong, Yang, Zichao, Xu, Chenglong, Zhao, Huiting, Liu, Jin, Chen, Jingxuan, Chen, Jianjun

“…[Display omitted] •KRas G12C-IN-3-based PROTACs were designed as degraders of endogenous KRAS G12C.•KP-14 showed the highest KRAS G12C-degrading capability in…”
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Direct Alkenylation of 2‐Methylquinolines with Aldehydes through Synergistic Catalysis of 1,3‐Dimethylbarbituric Acid and HOAc by Liang, En, Wang, Junqi, Wu, Yinrong, Huang, Liangbin, Yao, Xingang, Tang, Xiaodong

“…An efficient and practical direct alkenylation of 2‐methylquinolines with aldehydes has been achieved through a novel synergistic organocatalysis. The HOAc‐…”
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Corrigendum to “Discovery of KRas G12C-IN-3 and Pomalidomide-based PROTACs as degraders of endogenous KRAS G12C with potent anticancer activity” [Bioorgan. Chem. 117 (2021) 105447] by Li, Ling, Wu, Yinrong, Yang, Zichao, Xu, Chenglong, Zhao, Huiting, Liu, Jin, Chen, Jingxuan, Chen, Jianjun

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Corrigendum to "Discovery of KRas G12C-IN-3 and Pomalidomide-based PROTACs as degraders of endogenous KRAS G12C with potent anticancer activity" Bioorgan. Chem. 117 (2021) 105447 by Li, Ling, Wu, Yinrong, Yang, Zichao, Xu, Chenglong, Zhao, Huiting, Liu, Jin, Chen, Jingxuan, Chen, Jianjun

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Metal-free synthesis of 1,4-benzodiazepines and quinazolinones from hexafluoroisopropyl 2-aminobenzoates at room temperature by Chen, Jiewen, Liang, En, Shi, Jie, Wu, Yinrong, Wen, Kangmei, Yao, Xingang, Tang, Xiaodong

“…Herein, we describe the novel reactivity of hexafluoroisopropyl 2-aminobenzoates. The metal-free synthesis of 1,4-benzodiazepines and quinazolinones from…”
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Cell-free protein synthesis of CD1E and B2M protein and in vitro interaction by Tang, Yajie, Ma, Shengming, Lin, Sen, Wu, Yinrong, Chen, Siyang, Liu, Gang, Ma, Lisong, Wang, Zaihua, Jiang, Lele, Wang, Yao

“…CD1E, one of the most important glycolipid antigens on T cell membranes, is required for glycolipid antigen presentation on the cell surface. Cell-based…”
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A transmembrane scaffold from CD20 helps recombinant expression of a chimeric claudin 18.2 in an in vitro coupled transcription and translation system by Wang, Yao, Weng, Shaoting, Tang, Yajie, Lin, Sen, Liu, Xiayue, Zhang, Wenhui, Liu, Gang, Pandi, Boomi, Wu, Yinrong, Ma, Lei, Wang, Lin

“…Cluster of differentiation 20 (CD20) is a nonglycosylated, multispanning transmembrane protein specifically integrated by B lymphocytes. Similar to CD20,…”
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Multi-target tracking method with flexibility of illumination change by Yinrong Wu, Jianxiu Jin, Xiaofen Xing

“…Moving multi-targets tracking under variant illumination in a large range is still not highly robust, especially in changeable scenes of video sequence. In…”
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Acid‐Catalyzed Synthesis of Quinoline Derivatives from 2‐Methylquinolines and 2‐Aryloxy/Alkoxybenzaldehyde in Aqueous Medium by Wu, Yinrong, Lu, Xianchen, Wang, Hang, Liang, En, Yuan, Yingying, Zhao, Qiaorun, Zhu, Zhongzhi, Huang, Jiaping, Tang, Xiaodong

“…A HOAc‐catalyzed aryloxy/alkoxy‐assisted nucleophilic addition of 2‐methylquinolines to aldehydes in water has been described. With this highly environmentally…”
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The Monocyte-to-High-Density Lipoprotein Cholesterol Ratio as a Novel Predictor of the Prevalence of Senile Osteoporosis by Lin, Nan, Li, Dang, Lin, Si, Ke, Yilang, Lu, Jianping, Wu, Yinrong, Huang, Tianwen, Hong, Huashan

“…The prevalence of osteoporosis in elderly individuals is high, and osteoporosis is strongly associated with chronic inflammation. The monocyte-to-high-density…”
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