Search Results - "Wu, William K.K."

Trends in Incidence and Clinical Outcomes of Clostridioides difficile Infection, Hong Kong by Guo, Cosmos L T, Kwong, Thomas N Y, Mak, Joyce W Y, Zhang, Lin, Lui, Grace C Y, Wong, Grace L H, Ip, Margaret, Yu, Jun, Sung, Joseph J Y, Wu, William K K, Wong, Sunny H

“…We conducted a territorywide survey to investigate the epidemiology, risk factors, and clinical outcomes of Clostridioides difficile infection (CDI) among…”
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Dysregulation and crosstalk of cellular signaling pathways in colon carcinogenesis by Wu, William K.K, Wang, Xiao J, Cheng, Alfred S.L, Luo, Millore X.M, Ng, Simon S.M, To, Ka F, Chan, Francis K.L, Cho, Chi H, Sung, Joseph J.Y, Yu, Jun

“…Abstract Multiple intracellular signaling pathways, such as Wnt/β-catenin signaling, epidermal growth factor receptor/Ras signaling, and p53 signaling are…”
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MicroRNA-10b downregulation mediates acute rejection of renal allografts by derepressing BCL2L11 by Liu, Xiaoyou, Dong, Changgui, Jiang, Zhengyao, Wu, William K.K., Chan, Matthew T.V., Zhang, Jie, Li, Haibin, Qin, Ke, Sun, Xuyong

“…Kidney transplantation is the major therapeutic option for end-stage kidney diseases. However, acute rejection could cause allograft loss in some of these…”
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Disease Burden of Clostridium difficile Infections in Adults, Hong Kong, China, 2006-2014 by Ho, Jeffery, Dai, Rudin Z W, Kwong, Thomas N Y, Wang, Xiansong, Zhang, Lin, Ip, Margaret, Chan, Raphael, Hawkey, Peter M K, Lam, Kelvin L Y, Wong, Martin C S, Tse, Gary, Chan, Matthew T V, Chan, Francis K L, Yu, Jun, Ng, Siew C, Lee, Nelson, Wu, Justin C Y, Sung, Joseph J Y, Wu, William K K, Wong, Sunny H

“…Cross-sectional studies suggest an increasing trend in incidence and relatively low recurrence rates of Clostridium difficile infections in Asia than in Europe…”
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Cigarette Smoking and the Risk of Colorectal Cancer: A Meta-analysis of Prospective Cohort Studies by Tsoi, Kelvin K.F, Pau, Carol Y.Y, Wu, William K.K, Chan, Francis K.L, Griffiths, Sian, Sung, Joseph J.Y

“…Background & Aims Smoking has been implicated in many malignant diseases, but its association with colorectal cancer (CRC) is controversial. We quantitatively…”
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Clostridium difficile toxin B induces autophagic cell death in colonocytes by Chan, Hung, Zhao, Shan, Zhang, Lin, Ho, Jeffery, Leung, Czarina C.H., Wong, Wai T., Tian, Yuanyuan, Liu, Xiaodong, Kwong, Thomas N.Y., Chan, Raphael C.Y., Yu, Sidney S.B., Wang, Maggie H.T., Tse, Gary, Wong, Sunny H., Chan, Matthew T.V., Wu, William K.K.

“…Toxin B (TcdB) is a major pathogenic factor of Clostridum difficile. However, the mechanism by which TcdB exerts its cytotoxic action in host cells is still…”
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Co-inhibition of microRNA-10b and microRNA-21 exerts synergistic inhibition on the proliferation and invasion of human glioma cells by DONG, CHANG G, WU, WILLIAM K.K, FENG, SU Y, WANG, XIAO J, SHAO, JUN F, QIAO, JIAN

“…MicroRNAs (miRNAs) are small non-coding RNAs that function as negative gene regulators. Alterations in the expression of miRNAs have been implicated in the…”
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Genome-wide association and sequencing studies on colorectal cancer by Wong, Sunny H, Sung, Joseph J.Y, Chan, Francis K.L, To, Ka F, Ng, Simon S.M, Wang, Xiao J, Yu, Jun, Wu, William K.K

“…Abstract Colorectal cancer is a leading cause of morbidity and mortality worldwide. Understanding its genetic mechanisms is key to improving risk prediction,…”
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Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) in clinical practice by Li, Ka Hou Christien, Bazoukis, George, Liu, Tong, Li, Guangping, Wu, William K. K., Wong, Sunny Hei, Wong, Wing Tak, Chan, Yat Sun, Wong, Martin C. S., Wassilew, Katharina, Vassiliou, Vassilios S., Tse, Gary

“…Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is an inherited myocardial disease characterized by fibro‐fatty replacement of the right…”
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Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer by Kwong, Thomas N.Y., Wang, Xiansong, Nakatsu, Geicho, Chow, Tai Cheong, Tipoe, Timothy, Dai, Rudin Z.W., Tsoi, Kelvin K.K., Wong, Martin C.S., Tse, Gary, Chan, Matthew T.V., Chan, Francis K.L., Ng, Siew C., Wu, Justin C.Y., Wu, William K.K., Yu, Jun, Sung, Joseph J.Y., Wong, Sunny H.

“…Colorectal cancer (CRC) development has been associated with increased proportions of Bacteroides fragilis and certain Streptococcus, Fusobacterium, and…”
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miRNAs in gastrointestinal and liver cancers: their perspectives and clinical applications by Shen, Jing, Wu, William K K, Ren, Shun X, Zhang, Lin, Chan, Ruby L Y, Wong, Clover C M, Lu, Lan, Cho, Chi H

“…MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally. They have been found to be dysregulated in many pathological…”
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The Pharmacological Actions of Nicotine on the Gastrointestinal Tract by Wu, William K.K., Cho, Chi Hin

“…Increasing use of tobacco and its related health problems are a great concern in the world. Recent epidemiological findings have demonstrated the positive…”
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Dexamethasone delays ulcer healing by inhibition of angiogenesis in rat stomachs by Luo, Jiing C, Shin, Vivian Y, Liu, Edgar S.L, Ye, Yi N, Wu, William K.K, So, Wallace H.L, Chang, Full Y, Cho, Chi H

“…Using the non-ulcerogenic doses of dexamethasone, we explored the action of glucocorticoids on ulcer healing and its relationship with angiogenic factors in…”
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Autophagy in intracellular bacterial infection by Hu, Wei, Chan, Hung, Lu, Lan, Wong, Kam Tak, Wong, Sunny H., Li, Ming X., Xiao, Zhan G., Cho, Chi H., Gin, Tony, Chan, Matthew T.V., Wu, William K.K., Zhang, Lin

“…Autophagy is a conserved intracellular degradation process enclosing the bulk of cytosolic components for lysosomal degradation to maintain cellular…”
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Patent foramen ovale closure versus medical therapy for stroke prevention: A systematic review and meta-analysis of randomized controlled trials by Lai, Jenny Chi Ling, Tse, Gary, Wu, William K.K., Gong, Mengqi, Bazoukis, George, Wong, Wing Tak, Wong, Sunny Hei, Lampropoulos, Konstantinos, Baranchuk, Adrian, Tse, Lap Ah, Xia, Yunlong, Li, Guangping, Wong, Martin C.S., Chan, Yat Sun, Mu, Nan, Dong, Mei, Liu, Tong

“…Background: Previous randomized trials on patent foramen ovale (PFO) closure versus medical therapy for stroke prevention were inconclusive. Recently, two new…”
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Fibroblast growth factor 21 in cardio-metabolic disorders: a systematic review and meta-analysis by Lakhani, Ishan, Gong, Mengqi, Wong, Wing Tak, Bazoukis, George, Lampropoulos, Konstantinos, Wong, Sunny Hei, Wu, William K.K., Wong, Martin C.S., Ong, Kwok-Leung, Liu, Tong, Tse, Gary

“…Fibroblast growth factor 21 is a signalling protein involved in cell differentiation, morphogenesis, proliferation and metabolism. Recent studies have…”
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NOVA1 acts as an oncogene in melanoma via regulating FOXO3a expression by Yu, Xin, Zheng, Heyi, Chan, Matthew T.V., Wu, William K.K.

“…Increasing studies have suggested that dysregulation of RNA‐binding proteins (RBPs) contributes to cancer progression. Neuro‐oncological ventral antigen 1…”
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Pentraxin-3 as a marker of sepsis severity and predictor of mortality outcomes: A systematic review and meta-analysis by Lee, Yee Ting, Gong, Mengqi, Chau, Alex, Wong, Wing Tak, Bazoukis, George, Wong, Sunny Hei, Lampropoulos, Konstantinos, Xia, Yunlong, Li, Guangping, Wong, Martin C.S., Liu, Tong, Wu, William K.K., Tse, Gary

“…Pentraxin-3 (PTX-3) is a multi-functional pattern recognition molecule produced by various cell types of peripheral tissues in different infections. It is…”
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Sensitivity of apoptosis-resistant colon cancer cells to tanshinones is mediated by autophagic cell death and p53-independent cytotoxicity by Hu, Tao, Wang, Lin, Zhang, Lin, Lu, Lan, Shen, Jing, Chan, Ruby L.Y., Li, Mingxing, Wu, William K.K., To, Kenneth K.W., Cho, Chi Hin

“…Multidrug resistance (MDR) develops in nearly all patients with colon cancer. The reversal of MDR plays an important role in the success of colon cancer…”
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Frailty and Mortality Outcomes After Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis by Tse, Gary, Gong, Mengqi, Nunez, Julia, Sanchis, Juan, Li, Guangping, Ali-Hasan-Al-Saegh, Sadeq, Wong, Wing Tak, Wong, Sunny Hei, Wu, William K.K., Bazoukis, George, Yan, Gan-Xin, Lampropoulos, Konstantinos, Baranchuk, Adrian M., Tse, Lap Ah, Xia, Yunlong, Liu, Tong, Woo, Jean

“…Frailty has been identified as a risk factor for mortality. However, whether frailty increases mortality risk in patients undergoing percutaneous coronary…”
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