Search Results - "Wu, Weikun"
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Computational Prediction of Mutational Effects on SARS-CoV‑2 Binding by Relative Free Energy Calculations
Published in Journal of chemical information and modeling (28-12-2020)“…The ability of coronaviruses to infect humans is invariably associated with their binding strengths to human receptor proteins. Both SARS-CoV-2, initially…”
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Single point mutations can potentially enhance infectivity of SARS-CoV-2 revealed by in silico affinity maturation and SPR assay
Published in RSC advances (15-04-2021)“…The RBD (receptor binding domain) of the SARS-CoV-2 virus S (spike) protein mediates viral cell attachment and serves as a promising target for therapeutics…”
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Selective ensemble learning method for belief-rule-base classification system based on PAES
Published in Big Data Mining and Analytics (01-12-2019)“…Traditional Belief-Rule-Based (BRB) ensemble learning methods integrate all of the trained sub-BRB systems to obtain better results than a single…”
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The quality difference in five oolong tea accessions under different planting management patterns in south Fujian of China
Published in Frontiers in agronomy (08-05-2024)“…IntroductionOolong tea, celebrated for its significance in Chinese tea culture, was the subject of investigation in this study.MethodsFive varieties of Minnan…”
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Profiling of circulating serum exosomal microRNAs in elderly patients with infectious stress hyperglycaemia
Published in Clinical and translational discovery (01-08-2023)“…Background Early diagnosis of hospitalized elderly patients with infectious stress hyperglycaemia (ISH) is clinically important, especially under the global…”
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Improved thermostability of lipase Lip2 from Yarrowia lipolytica through disulfide bond design for preparation of medium-long-medium structured lipids
Published in Food science & technology (15-08-2022)“…Lipase Lip2 from Yarrowia lipolytica with great potential value in the enzymatic preparation of medium-long-medium structured lipids (MLM-SLs), but the…”
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Prediction of network pharmacology, molecular docking-based strategy, and vitro assays to determine potential pharmacological mechanism of Dioscoreae bulbiferae and Bruceae fructus against laryngocarcinoma
Published in Medicine (Baltimore) (22-12-2023)“…Based on network pharmacology, molecular docking, and vitro assays, investigate the probable pharmacological mechanism of Dioscoreae bulbiferae and Bruceae…”
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Enhancing thermostability of Yarrowia lipolytica lipase 2 through engineering multiple disulfide bonds and mitigating reduced lipase production associated with disulfide bonds
Published in Enzyme and microbial technology (01-07-2019)“…•Thermostability of Yarrowia lipolytica lipase 2 was enhanced by combining disulfide bonds.•Combining different regional disulfide bonds had greater effect…”
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CELSR3 is a prognostic marker in HNSCC and correlates with immune cell infiltration in the tumor microenvironment
Published in European archives of oto-rhino-laryngology (01-06-2024)“…Purpose To look at the diagnostic value of the CELSR receptor 3 ( CELSR3 ) gene in head and neck squamous cell carcinoma (HNSCC) and its effect on tumor immune…”
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Prediction of network pharmacology and molecular docking-based strategy to determine potential pharmacological mechanism of Liuwei Dihuang pill against tinnitus
Published in Medicine (Baltimore) (18-11-2022)“…Liuwei Dihuang Pill is widely used to treat tinnitus in China. However, the underlying mechanism of Liuwei Dihuang Pill in treating tinnitus still remains…”
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SLA2 is a prognostic marker in HNSCC and correlates with immune cell infiltration in the tumor microenvironment
Published in European archives of oto-rhino-laryngology (01-01-2024)“…Purpose To investigate Src-like adaptor 2 gene ( SLA2 ) expression in head and neck squamous cell carcinoma (HNSCC), its potential prognostic value, and its…”
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Single point mutations can potentially enhance infectivity of SARS-CoV-2 revealed by affinity maturation and SPR assay
Published in RSC advances (10-05-2021)“…The RBD (receptor binding domain) of the SARS-CoV-2 virus S (spike) protein mediates viral cell attachment and serves as a promising target for therapeutics…”
Get full text
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Edge Computing Device to Implement Integration of BMS Master Control and Battery Prognostic Safety System
Published in 2023 International Conference on Power System Technology (PowerCon) (21-09-2023)“…Drawbacks of traditional separate implementation of Battery Management System (BMS) master control and battery Prognostic Safety System (PSS) in different…”
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Conference Proceeding -
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SK-Net: Deep Learning on Point Cloud via End-to-end Discovery of Spatial Keypoints
Published 31-03-2020“…Since the PointNet was proposed, deep learning on point cloud has been the concentration of intense 3D research. However, existing point-based methods usually…”
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Optimal nonlinear–nonquadratic feedback control for nonlinear discrete-time systems with l and l disturbances
Published in Nonlinear analysis (01-07-2000)Get full text
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Analysis of nonlinear-nonquadratic discrete-time systems with /spl Lscr//sub 2/ and /spl Lscr//sub /spl infin// disturbances
Published in Proceedings of the 37th IEEE Conference on Decision and Control (Cat. No.98CH36171) (1998)“…A unified optimality-based framework is developed to address the problem of nonlinear-nonquadratic discrete time systems with bounded exogeneous disturbances…”
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Conference Proceeding