Search Results - "Wu, Tianding"

LncGBP9/miR-34a axis drives macrophages toward a phenotype conducive for spinal cord injury repair via STAT1/STAT6 and SOCS3 by Zhou, Jiahui, Li, Zhiyue, Wu, Tianding, Zhao, Qun, Zhao, Qiancheng, Cao, Yong

“…Acute spinal cord injury (SCI) could cause mainly two types of pathological sequelae, the primary mechanical injury, and the secondary injury. The macrophage…”
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Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain by Zhu, Shouan, Zhu, Jianxi, Zhen, Gehua, Hu, Yihe, An, Senbo, Li, Yusheng, Zheng, Qin, Chen, Zhiyong, Yang, Ya, Wan, Mei, Skolasky, Richard Leroy, Cao, Yong, Wu, Tianding, Gao, Bo, Yang, Mi, Gao, Manman, Kuliwaba, Julia, Ni, Shuangfei, Wang, Lei, Wu, Chuanlong, Findlay, David, Eltzschig, Holger K, Ouyang, Hong Wei, Crane, Janet, Zhou, Feng-Quan, Guan, Yun, Dong, Xinzhong, Cao, Xu

“…Joint pain is the defining symptom of osteoarthritis (OA) but its origin and mechanisms remain unclear. Here, we investigated an unprecedented role of…”
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Knockdown of SNHG1 alleviates autophagy and apoptosis by regulating miR-362-3p/Jak2/stat3 pathway in LPS-injured PC12 cells by Zhou, Jiahui, Li, Zhiyue, Zhao, Qun, Wu, Tianding, Zhao, Qiancheng, Cao, Yong

“…Spinal cord injury (SCI) is a serious neurological disease. Long non-coding RNA (lncRNA) small nucleolar RNA host gene (SNHG1) and microRNA-362-3p (miR-362-3p)…”
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The Long Non-coding RNA NEAT1/miR-224-5p/IL-33 Axis Modulates Macrophage M2a Polarization and A1 Astrocyte Activation by Liu, Dongliang, Wei, Yuehua, Liu, Yudong, Wu, Tianding, Hu, Jianzhong, Lu, Hongbin

“…To identify potential regulators and investigate the molecular mechanism of macrophage polarization affecting astrocyte activation from the perspective of…”
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Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice by Ni, Shuangfei, Ling, Zemin, Wang, Xiao, Cao, Yong, Wu, Tianding, Deng, Ruoxian, Crane, Janet L., Skolasky, Richard, Demehri, Shadpour, Zhen, Gehua, Jain, Amit, Wu, Panfeng, Pan, Dayu, Hu, Bo, Lyu, Xiao, Li, Yusheng, Chen, Hao, Qi, Huabin, Guan, Yun, Dong, Xinzhong, Wan, Mei, Zou, Xuenong, Lu, Hongbin, Hu, Jianzhong, Cao, Xu

“…Spinal pain is a major clinical problem, however, its origins and underlying mechanisms remain unclear. Here we report that in mice, osteoclasts induce sensory…”
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The Angiogenic Effect of microRNA-21 Targeting TIMP3 through the Regulation of MMP2 and MMP9 by Hu, Jianzhong, Ni, Shuangfei, Cao, Yong, Zhang, Tao, Wu, Tianding, Yin, Xianzhen, Lang, Ye, Lu, Hongbin

“…microRNAs are a novel set of small, non-protein-coding nucleotide RNAs that negatively regulate the expression of target mRNAs. miRNA-21 is a microRNA that is…”
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UTX/KDM6A Deletion Promotes Recovery of Spinal Cord Injury by Epigenetically Regulating Vascular Regeneration by Ni, Shuangfei, Luo, Zixiang, Jiang, Liyuan, Guo, Zhu, Li, Ping, Xu, Xiang, Cao, Yong, Duan, Chunyue, Wu, Tianding, Li, Chengjun, Lu, Hongbin, Hu, Jianzhong

“…The regeneration of the blood vessel system post spinal cord injury (SCI) is essential for the repair of neurological function. As a significant means to…”
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BMSCs‐Derived Exosomes Ameliorate Pain Via Abrogation of Aberrant Nerve Invasion in Subchondral Bone in Lumbar Facet Joint Osteoarthritis by Li, Jinsong, Ding, Zhiyu, Li, Yuezhan, Wang, Weiguo, Wang, Jianlong, Yu, Haiyang, Liu, Ansong, Miao, Jinglei, Chen, Shijie, Wu, Tianding, Cao, Yong

“…ABSTRACT Lumbar facet joint osteoarthritis (LFJ OA) is regarded as one of the common causes of low back pain (LBP). The pathogenesis and underlying mechanism…”
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Three-dimensional imaging of microvasculature in the rat spinal cord following injury by Cao, Yong, Wu, Tianding, yuan, Zhou, Li, Dongzhe, Ni, Shuangfei, Hu, Jianzhong, Lu, Hongbin

“…Research studies on the three-dimensional (3D) morphological alterations of the spinal cord microvasculature after injury provide insight into the pathology of…”
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High‐resolution three‐dimensional visualization of the rat spinal cord microvasculature by synchrotron radiation micro‐CT by Hu, Jianzhong, Cao, Yong, Wu, Tianding, Li, Dongzhe, Lu, Hongbin

“…Purpose: Understanding the three‐dimensional (3D) morphology of the spinal cord microvasculature has been limited by the lack of an effective high‐resolution…”
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Mechanical overloading-induced miR-325-3p reduction promoted chondrocyte senescence and exacerbated facet joint degeneration by Zhao, Jinyun, Li, Chengjun, Qin, Tian, Jin, Yuxin, He, Rundong, Sun, Yi, Liu, Zhide, Wu, Tianding, Duan, Chunyue, Cao, Yong, Hu, Jianzhong

“…Lumbar facet joint (LFJ) degeneration is one of the main causes of low back pain (LBP). Mechanical stress leads to the exacerbation of LFJ degeneration, but…”
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3D Digital Anatomic Angioarchitecture of the Rat Spinal Cord: A Synchrotron Radiation Micro-CT Study by Li, Ping, Xu, Yan, Cao, Yong, Wu, Tianding

“…Comprehensive analysis of 3D angioarchitecture within the intact rat spinal cord remains technically challenging due to its sophisticated anatomical…”
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Hypoxia-treated adipose mesenchymal stem cell-derived exosomes attenuate lumbar facet joint osteoarthritis by Zhao, Jinyun, Sun, Yi, Sheng, Xiaolong, Xu, Jiaqi, Dai, Guoyu, He, Rundong, Jin, Yuxin, Liu, Zhide, Xie, Yong, Wu, Tianding, Cao, Yong, Hu, Jianzhong, Duan, Chunyue

“…Abstract Background Lumbar facet joint osteoarthritis (LFJ OA) is a common disease, and there is still a lack of effective disease-modifying therapies. Our aim…”
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Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway by Xie, Yong, Luo, Zixiang, Peng, Wei, Liu, Yudong, Yuan, Feifei, Xu, Jiaqi, Sun, Yi, Lu, Hongbin, Wu, Tianding, Jiang, Liyuan, Hu, Jianzhong

“…Abstract Spinal cord injury (SCI) can prompt an immediate disruption to the blood–spinal cord barrier (BSCB). Restoring the integrity of this barrier is vital…”
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Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Accelerate Functional Recovery After Spinal Cord Injury by Promoting the Phagocytosis of Macrophages to Clean Myelin Debris by Sheng, Xiaolong, Zhao, Jinyun, Li, Miao, Xu, Yan, Zhou, Yi, Xu, Jiaqi, He, Rundong, Lu, Hongbin, Wu, Tianding, Duan, Chunyue, Cao, Yong, Hu, Jianzhong

“…Macrophage phagocytosis contributes predominantly to processing central nervous system (CNS) debris and further facilitates neurological function restoration…”
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Genetic factors of cervical spondylotic myelopathy-a systemic review by Wang, Guohua, Cao, Yong, Wu, Tianding, Duan, Chunyue, Wu, Jianhuang, Hu, Jianzhong, Lu, Hongbin

“…•The polymorphisms of 6 genes were associated with CSM.•The polymorphisms of 3 genes were associated with the postoperative outcome.•The polymorphism of BDNF,…”
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Unilateral Limited Laminectomy for Debridement to Treat Localized Short‐Segment Lumbosacral Spinal Tuberculosis: A Retrospective Case Series by Li, Miao, Huang, Jianjun, Chen, Jinbiao, Liu, Shaohua, Deng, Zhansheng, Hu, Jianzhong, Cao, Yong, Wu, Tianding

“…Objective This study aimed to investigate the clinical effects of surgically treating lumbosacral tuberculosis with a modified posterior unilateral limited…”
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Kdm6a-CNN1 axis orchestrates epigenetic control of trauma-induced spinal cord microvascular endothelial cell senescence to balance neuroinflammation for improved neurological repair by Li, Chengjun, Qin, Tian, Zhao, Jinyun, Jin, Yuxin, Qin, Yiming, He, Rundong, Wu, Tianding, Duan, Chunyue, Jiang, Liyuan, Yuan, Feifei, Lu, Hongbin, Cao, Yong, Hu, Jianzhong

“…Cellular senescence assumes pivotal roles in various diseases through the secretion of proinflammatory factors. Despite extensive investigations into vascular…”
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Author Correction: Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice by Ni, Shuangfei, Ling, Zemin, Wang, Xiao, Cao, Yong, Wu, Tianding, Deng, Ruoxian, Crane, Janet L., Skolasky, Richard, Demehri, Shadpour, Zhen, Gehua, Jain, Amit, Wu, Panfeng, Pan, Dayu, Hu, Bo, Lyu, Xiao, Li, Yusheng, Chen, Hao, Qi, Huabin, Guan, Yun, Dong, Xinzhong, Wan, Mei, Zou, Xuenong, Lu, Hongbin, Hu, Jianzhong, Cao, Xu

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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3D angioarchitecture of spinal cord in a rat model detected by synchrotron radiation micro-computed tomography by Cao, Yong, Hu, Jianzhong, Wu, Tianding, Li, Dongzhe, Lu, Hongbin

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