Search Results - "Wu, T John"

Chronically stressed male and female mice show a similar peripheral and central pro-inflammatory profile after an immune challenge by Bodemeier Loayza Careaga, Mariella, Wu, T John

“…Although acute stressors are known for stimulating the production of glucocorticoids and pro-inflammatory cytokines in rodents, the effects of chronic…”
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The Effects of Chronic Variable Stress and Photoperiod Alteration on the Hypothalamic–Pituitary–Adrenal Axis Response and Behavior of Mice by Miller, Lauren, Careaga, Mariella Bodemeier Loayza, Handa, Robert J., Wu, T. John

“…•Chronic variable stress attenuated the HPA axis reactivity in response to an acute stressor.•Chronic variable stress decreased body weight.•Key regulators of…”
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Gigantism and Acromegaly Due to Xq26 Microduplications and GPR101 Mutation by Trivellin, Giampaolo, Daly, Adrian F, Faucz, Fabio R, Yuan, Bo, Rostomyan, Liliya, Larco, Darwin O, Schernthaner-Reiter, Marie Helene, Szarek, Eva, Leal, Letícia F, Caberg, Jean-Hubert, Castermans, Emilie, Villa, Chiara, Dimopoulos, Aggeliki, Chittiboina, Prashant, Xekouki, Paraskevi, Shah, Nalini, Metzger, Daniel, Lysy, Philippe A, Ferrante, Emanuele, Strebkova, Natalia, Mazerkina, Nadia, Zatelli, Maria Chiara, Lodish, Maya, Horvath, Anelia, de Alexandre, Rodrigo Bertollo, Manning, Allison D, Levy, Isaac, Keil, Margaret F, Sierra, Maria de la Luz, Palmeira, Leonor, Coppieters, Wouter, Georges, Michel, Naves, Luciana A, Jamar, Mauricette, Bours, Vincent, Wu, T. John, Choong, Catherine S, Bertherat, Jerome, Chanson, Philippe, Kamenický, Peter, Farrell, William E, Barlier, Anne, Quezado, Martha, Bjelobaba, Ivana, Stojilkovic, Stanko S, Wess, Jurgen, Costanzi, Stefano, Liu, Pengfei, Lupski, James R, Beckers, Albert, Stratakis, Constantine A

“…A duplicated segment of the X chromosome causes pediatric gigantism through increased levels of growth hormone. A gene in the duplicated region that encodes a…”
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Editorial: The bidirectional relationship between sleep and neuroendocrinology by Suchecki, Deborah, Meerlo, Peter, Wu, T John

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Alterations in the activation of corticotropin-releasing factor neurons in the paraventricular nucleus following a single or multiple days of sleep restriction by Buban, Katelyn N., Saperstein, Samantha E., Oyola, Mario G., Rothwell, Stephen W., John Wu, T.

“…•Sleep restriction suppresses CRF neuronal activation.•Sleep restriction suppresses paraventricular nucleus activation.•Sleep restriction attenuates neuronal…”
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Knockout of the circadian gene, Per2, disrupts corticosterone secretion and results in depressive-like behaviors and deficits in startle responses by Russell, Ashley L, Miller, Lauren, Yi, Hannah, Keil, Rita, Handa, Robert J, Wu, T John

“…The Period Circadian Regulator 2 (Per2) gene is important for the modulation of circadian rhythms that influence biological processes. Circadian control of the…”
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The role of GnRH metabolite, GnRH-(1-5), in endometrial cancer by Cho-Clark, Madelaine J, Watkins, Allison, Wu, T John

“…From the time of its discovery and isolation in the mammalian hypothalamus, the decapeptide, gonadotropin-releasing hormone (GnRH), has also been found to be…”
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RNA-sequencing of AVPV and ARH reveals vastly different temporal and transcriptomic responses to estradiol in the female rat hypothalamus by Mohr, Margaret A, Wong, Angela M, Sukumar, Gauthaman, Dalgard, Clifton L, Hong, Weizhe, Wu, T John, Wu, Ye Emily, Micevych, Paul E

“…In females, estrogens have two main modes of action relating to gonadotropin secretion: positive feedback and negative feedback. Estrogen positive and negative…”
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GnRH-(1–5) Transactivates EGFR in Ishikawa Human Endometrial Cells via an Orphan G Protein-Coupled Receptor by Cho-Clark, Madelaine, Larco, Darwin O, Semsarzadeh, Nina N, Vasta, Florencia, Mani, Shaila K, Wu, T. John

“…The decapeptide GnRH is known for its central role in the regulation of the hypothalamo-pituitary-gonadal axis. In addition, it is also known to have local…”
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Comparative transcriptome analysis between patient and endometrial cancer cell lines to determine common signaling pathways and markers linked to cancer progression by Cho-Clark, Madelaine J, Sukumar, Gauthaman, Vidal, Newton Medeiros, Raiciulescu, Sorana, Oyola, Mario G, Olsen, Cara, Mariño-Ramírez, Leonardo, Dalgard, Clifton L, Wu, T John

“…The rising incidence and mortality of endometrial cancer (EC) in the United States calls for an improved understanding of the disease's progression. Current…”
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Isoflavones Alter Hypothalamic–Pituitary–Adrenal Axis Response Following Photoperiod Alteration by Bauman, Bradly M., Buban, Katelyn N., Russell, Ashley L., Handa, Robert J., Wu, T. John

“…Photoperiod and diet are factors known to modulate the hypothalamic–pituitary–adrenal (HPA) axis. Specifically, shifts in photoperiod have been previously…”
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The Heart: A Novel Gonadotrophin-Releasing Hormone Target by Dong, F., Skinner, D. C., John Wu, T., Ren, J.

“…Gonadotrophin‐releasing hormone (GnRH) is a hypothalamic hormone transported by the hypophyseal portal bloodstream to the pituitary gland, where it binds to…”
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The interaction of dietary isoflavones and estradiol replacement on behavior and brain-derived neurotrophic factor in the ovariectomized rat by Russell, Ashley L., Grimes, Jamie Moran, Larco, Darwin O., Cruthirds, Danette F., Westerfield, Joanna, Wooten, Lawren, Keil, Margaret, Weiser, Michael J., Landauer, Michael R., Handa, Robert J., Wu, T. John

“…•E2 administration resulted in anxiogenic behaviors when dietary isoflavones were present.•E2 administration resulted in anxiolytic and anti-depressive like…”
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Regulation of Gonadotropin-Releasing Hormone-(1-5) Signaling Genes by Estradiol Is Age Dependent by Bauman, Bradly M, Yin, Weiling, Gore, Andrea C, Wu, T John

“…Gonadotropin-releasing hormone (GnRH) is a key regulatory molecule of the hypothalamus-pituitary (PIT)-gonadal (HPG) axis that ultimately leads to the…”
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Blast-Induced Mild Traumatic Brain Injury Alterations of Corticotropin-Releasing Factor Neuronal Activity in the Mouse Hypothalamic Paraventricular Nucleus by Simmons, Sarah, Langlois, Ludovic D, Oyola, Mario G, Gouty, Shawn, Wu, T John, Nugent, Fereshteh S

“…Blast-induced mild traumatic brain injury (mbTBI) is the most common cause of TBI in US service members and veterans. Those exposed to TBI are at greater risk…”
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CM-MM and ACE genotypes and physiological prediction of the creatine kinase response to exercise by Heled, Yuval, Bloom, Michael S, Wu, T. John, Stephens, Quiona, Deuster, Patricia A

“…Departments of 1 Military and Emergency Medicine and of 2 Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda; and 3…”
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Cuprizone demyelination of the corpus callosum in mice correlates with altered social interaction and impaired bilateral sensorimotor coordination by Hibbits, Norah, Pannu, Ravinder, Wu, T John, Armstrong, Regina C

“…For studies of remyelination in demyelinating diseases, the cuprizone model of CC (corpus callosum) demyelination has experimental advantages that include…”
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Sleep Deprivation Alters the Pituitary Stress Transcriptome in Male and Female Mice by Oyola, Mario G., Shupe, Elizabeth A., Soltis, Anthony R., Sukumar, Gauthaman, Paez-Pereda, Marcelo, Larco, Darwin O., Wilkerson, Matthew D., Rothwell, Stephen, Dalgard, Clifton L., Wu, T. John

“…Poor sleep hygiene is a growing problem, with detrimental effects on many biological systems. The pituitary gland plays a crucial role in the regulation of…”
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GnRH-(1-5) Inhibits TGF-β Signaling to Regulate the Migration of Immortalized Gonadotropin-Releasing Hormone Neurons by Larco, Darwin O, Bauman, Bradly M, Cho-Clark, Madelaine, Mani, Shaila K, Wu, T John

“…Gonadotropin-releasing hormone (GnRH) neurons originate outside the central nervous system (CNS) in the nasal placode where their migration to the basal…”
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Is the metalloendopeptidase EC 3.4.24.15 (EP24.15), the enzyme that cleaves luteinizing hormone-releasing hormone (LHRH), an activating enzyme? by Cleverly, Kirsty, Wu, T John

“…LHRH (GNRH) was first isolated in the mammalian hypothalamus and shown to be the primary regulator of the reproductive neuroendocrine axis comprising of the…”
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