Search Results - "Wu, Songfeng"
-
1
Molecular evolution in different subtypes of multifocal hepatocellular carcinoma
Published in Hepatology international (01-12-2023)“…Background Multifocal hepatocellular carcinoma (MF-HCC) accounts for > 40% of HCCs, exhibiting a poor prognosis than single primary HCCs. Characterizing…”
Get full text
Journal Article -
2
Longitudinal Serum Proteome Characterization of COVID-19 Patients With Different Severities Revealed Potential Therapeutic Strategies
Published in Frontiers in immunology (26-07-2022)“…The COVID-19 pandemic caused by SARS-CoV-2 is exerting huge pressure on global healthcare. Understanding of the molecular pathophysiological alterations in…”
Get full text
Journal Article -
3
Proteome Analysis of Hepatocellular Carcinoma by Two-dimensional Difference Gel Electrophoresis
Published in Molecular & cellular proteomics (01-10-2007)“…Hepatocellular carcinoma (HCC) is a highly malignant tumor, and chronic infection with hepatitis B virus is one of its major risk factors. To identify the…”
Get full text
Journal Article -
4
BioLadder: A bioinformatic platform primarily focused on proteomic data analysis
Published in iMeta (01-08-2024)“…BioLadder (https://www.bioladder.cn/) is an online data analysis platform designed for proteomics research, which includes three classes of experimental data…”
Get full text
Journal Article -
5
Functional proteomic analysis of nonalcoholic fatty liver disease in rat models: Enoyl–coenzyme a hydratase down‐regulation exacerbates hepatic steatosis
Published in Hepatology (Baltimore, Md.) (01-04-2010)“…Nonalcoholic fatty liver disease (NAFLD) has emerged as a common public health problem that can progress to end‐stage liver disease. A high‐fat diet (HFD) may…”
Get full text
Journal Article -
6
Validation of a multi-omics strategy for prioritizing personalized candidate driver genes
Published in Oncotarget (21-06-2016)“…Significant heterogeneity between different tumors prevents the discovery of cancer driver genes, especially in a patient-specific manner. We previously…”
Get full text
Journal Article -
7
PepDistiller: A quality control tool to improve the sensitivity and accuracy of peptide identifications in shotgun proteomics
Published in Proteomics (Weinheim) (01-06-2012)“…In this study, we presented a quality control tool named PepDistiller to facilitate the validation of MASCOT search results. By including the number of tryptic…”
Get full text
Journal Article -
8
Bayesian Nonparametric Model for the Validation of Peptide Identification in Shotgun Proteomics
Published in Molecular & cellular proteomics (01-03-2009)“…Tandem mass spectrometry combined with database searching allows high throughput identification of peptides in shotgun proteomics. However, validating database…”
Get full text
Journal Article -
9
Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles
Published in PloS one (28-10-2009)“…In fetal hematopoietic organs, the switch from hematopoiesis is hypothesized to be a critical time point for organogenesis, but it is not yet evidenced. The…”
Get full text
Journal Article -
10
Regular patterns for proteome-wide distribution of protein abundance across species
Published in PloS one (09-03-2012)“…A proteome of the bio-entity, including cell, tissue, organ, and organism, consists of proteins of diverse abundance. The principle that determines the…”
Get full text
Journal Article -
11
Improving the sensitivity of MASCOT search results validation by combining new features with Bayesian nonparametric model
Published in Proteomics (Weinheim) (01-12-2010)“…The probability‐based search engine MASCOT has been widely used to identify peptides and proteins in shotgun proteomic research. Most subsequent quality…”
Get full text
Journal Article -
12
Computational identification of rare codons of Escherichia coli based on codon pairs preference
Published in BMC bioinformatics (28-01-2010)“…Codon bias is believed to play an important role in the control of gene expression. In Escherichia coli, some rare codons, which can limit the expression level…”
Get full text
Journal Article -
13
Analysis of human liver proteome using replicate shotgun strategy
Published in Proteomics (Weinheim) (01-07-2007)“…In this study, a liquid‐based shotgun strategy was used to comprehensively identify the expression of human liver proteome. Proteins were extracted from human…”
Get full text
Journal Article -
14
A Dataset of Human Fetal Liver Proteome Identified by Subcellular Fractionation and Multiple Protein Separation and Identification Technology
Published in Molecular & cellular proteomics (01-09-2006)“…A high throughput process including subcellular fractionation and multiple protein separation and identification technology allowed us to establish the protein…”
Get full text
Journal Article -
15
Multi-modality of pI distribution in whole proteome
Published in Proteomics (Weinheim) (01-01-2006)“…Multi‐modality of pI distribution is a common feature in different whole proteomes. Some researchers considered it relate to the proteins with different…”
Get full text
Journal Article -
16
Asia Oceania Human Proteome Organisation Membrane Proteomics Initiative. Preparation and characterisation of the carbonate‐washed membrane standard
Published in Proteomics (Weinheim) (01-11-2010)“…The Asia Oceania Human Proteome Organisation (AOHUPO) has embarked on a Membrane Proteomics Initiative with goals of systematic comparison of strategies for…”
Get full text
Journal Article -
17
Proteomic analysis on structural proteins of Severe Acute Respiratory Syndrome coronavirus
Published in Proteomics (Weinheim) (01-02-2004)“…Recently, a new coronavirus was isolated from the lung tissue of autopsy sample and nasal/throat swabs of the patients with Severe Acute Respiratory Syndrome…”
Get full text
Journal Article -
18
iProX: an integrated proteome resource
Published in Nucleic acids research (08-01-2019)“…Abstract Sharing of research data in public repositories has become best practice in academia. With the accumulation of massive data, network bandwidth and…”
Get full text
Journal Article -
19
Protein probabilities in shotgun proteomics: Evaluating different estimation methods using a semi-random sampling model
Published in Proteomics (Weinheim) (01-12-2006)“…The calculation of protein probabilities is one of the most intractable problems in large‐scale proteomic research. Current available estimating methods, for…”
Get full text
Journal Article -
20
iProX in 2021: connecting proteomics data sharing with big data
Published in Nucleic acids research (07-01-2022)“…Abstract The rapid development of proteomics studies has resulted in large volumes of experimental data. The emergence of big data platform provides the…”
Get full text
Journal Article