Search Results - "Wu, Shuangjie"

Optimization of novel benzofuro[3,2-b]pyridin-2(1H)-one derivatives as dual inhibitors of BTK and PI3Kδ by Liu, Linyi, Li, Xinyu, Cheng, Yu, Wang, Lianjian, Yang, Huizhu, Li, Jiurong, He, Siying, shuangjie Wu, Yin, Qianqian, Xiang, Hua

“…BTK and PI3Kδ play crucial roles in the progression of leukemia, and studies confirmed that the dual inhibition against BTK and PI3Kδ could provide superior…”
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SKAP1 Expression in Cancer Cells Enhances Colon Tumor Growth and Impairs Cytotoxic Immunity by Promoting Neutrophil Extracellular Trap Formation via the NFATc1/CXCL8 Axis by Gao, Jian, Liu, Jun, Lu, Jilin, Zhang, Xiaofei, Zhang, Wei, Li, Qian, Cai, Jiayi, Li, Mengjun, Gan, Yu, Tang, Yifan, Wu, Shuangjie

“…The mechanisms underlying the development and progression of colon cancer are not fully understood. Herein, Src kinase associated phosphoprotein 1 (SKAP1), an…”
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PIK3CA mutation is associated with poor survival among patients with metastatic colorectal cancer following anti-EGFR monoclonal antibody therapy: a meta-analysis by Wu, Shuangjie, Gan, Yu, Wang, Xinhai, Liu, Jun, Li, Mengjun, Tang, Yifan

“…Purpose PIK3CA mutation appears to predict a lack of response to anti-EGFR monoclonal antibody (mAb) treatment in patients with metastatic colorectal cancer…”
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Onion-like carbon nanoparticles as additives in lubricant oil deform inelastically during the wear testing for improved lubrication performances by Dai, Yijun, Feng, Xiaohua, Liu, Yi, Huang, Jing, Wu, Shuangjie, Zhou, Ping, Li, Hua

“…Nano-carbon has been extensively investigated as an additive to lubricant oil for improved performance. It is still far from a final verdict as to how the…”
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High microwave absorption performance in Nd-substituted BaM/GO through sol-gel and high energy ball milling process by Liu, Jinjie, Feng, Xiaohua, Wu, Shuangjie, Zhou, Ping, Huang, Jing, Li, Hua, Liang, Tongxiang

“…In this paper, a series of compound materials with different proportions of rare earth neodymium (Nd) doped M-type barium ferrite (BaM) and the mixture Nd-BaM…”
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Development of novel tetrahydroisoquinoline-hydroxamate conjugates as potent dual SERDs/HDAC inhibitors for the treatment of breast cancer by Luo, Guoshun, Lin, Xin, Ren, Shengnan, Wu, Shuangjie, Wang, Xin, Ma, Luyu, Xiang, Hua

“…Concomitant inhibition of estrogen receptor alpha (ERα) and histone deacetylase (HDAC) signaling has been proven effective in endocrine-resistant ER+ breast…”
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Design and synthesis of novel benzothiophene analogs as selective estrogen receptor covalent antagonists against breast cancer by Bai, Chengfeng, Ren, Shengnan, Wu, Shuangjie, Zhu, Meiqi, Luo, Guoshun, Xiang, Hua

“…Endocrine therapy (ET) has benefited patients with estrogen receptor alpha (ERα) positive breast cancer for decades. Selective estrogen receptor modulator…”
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Benzothiophene derivatives as selective estrogen receptor covalent antagonists: Design, synthesis and anti-ERα activities by Bai, Chengfeng, Wu, Shuangjie, Ren, Shengnan, Zhu, Meiqi, Luo, Guoshun, Xiang, Hua

“…[Display omitted] •Compound 19d exhibited potent antiproliferative effect in MCF-7 and Ishikawa cell lines in vitro.•19d could attenuate the expression of…”
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Effect of cavitation on corrosion behavior of HVOF-sprayed WC-10Co4Cr coating with post-sealing in artificial seawater by Tian, Ye, Zhang, Haijun, Chen, Xiuyong, McDonald, André, Wu, Shuangjie, Xiao, Tonghu, Li, Hua

“…This study aims to further improve the cavitation-corrosion performances of high-velocity oxygen-fuel (HVOF) sprayed WC-10Co4Cr coatings by post-sealing…”
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Synthesis and evaluation of novel thiosemicarbazone and semicarbazone analogs with both anti-proliferative and anti-metastatic activities against triple negative breast cancer by Bai, Chengfeng, Wu, Shuangjie, Ren, Shengnan, Zhu, Meiqi, Luo, Guoshun, Xiang, Hua

“…[Display omitted] •Hecogenin thiosemicarbazone and semicarbazone hybrids are helpful for design of triple-negative breast cancer agents.•4c possesses…”
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Association of obesity and overweight with overall survival in colorectal cancer patients: a meta-analysis of 29 studies by Wu, Shuangjie, Liu, Jun, Wang, Xinhai, Li, Mengjun, Gan, Yu, Tang, Yifan

“…Purpose: Previous studies that assessed the relationship between obesity, overweight, and survival in colorectal cancer (CRC) have provided conflicting…”
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Carbonized-nitridated Mo2N-MoC heterostructures towards universal-medium hydrogen evolution reaction by Chen, Xiang, Xie, Song, Zhou, Fang, Gao, Biao, Zhang, Xuming, Wu, Shuangjie, Huang, Li, Li, Yun, Chu, Paul K., Peng, Xiang

“…A one-step carbonization/nitridation technique is designed to synthesize the Mo2N-MoC heterostructure with strong electronic interactions as well as enhanced…”
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Degradation of curcumin‐mediated photodynamic technology (PDT) on polycyclic aromatic hydrocarbons in oysters and toxicity evaluation of PDT‐treated oysters by Zhi, Jinjin, Tang, Qingjuan, Wu, Shuangjie, Kong, Biao, Jiang, Jiali, Li, Zhaojie, Wang, Yuming, Xue, Changhu

“…Summary This study investigated the degradation effect of curcumin‐mediated photodynamic technology (PDT) on polycyclic aromatic hydrocarbons (PAHs) in…”
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Tailoring the Adsorption and Antibacterial Bifunctions of Newly Constructed Porous Alginate–Chitosan–Graphene Oxide Nanosheets Gel Beads by Wang, Songtao, Feng, Xiaohua, Liu, Yi, Huang, Jing, Zhou, Ping, Wu, Shuangjie, Zhang, Botao, Li, Hua

“…Organic dye molecules and pathogenic microorganisms exist widely in printing and dyeing wastewater, causing persisting concerns about water environment safety…”
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Identification of Core Prognosis-Related Candidate Genes in Chinese Gastric Cancer Population Based on Integrated Bioinformatics by Wu, Shuangjie, Wang, Zhouyu, Li, Dongbing, Mao, Xiang, Liu, Jun, Wang, Xinhai, Li, Mengjun, Tang, Yifan

“…Background. Gastric cancer (GC) is one of the leading causes of cancer-related mortality worldwide. There are great geographical differences in the incidence…”
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Suspension Flame Spray Construction of Porous Polycaprolactone/Hydroxyapatite Coatings for Marine Ecological Remediation by Xu, Zhiyuan, Feng, Xiaohua, Huang, Jing, Wu, Shuangjie, Zhou, Ping, Li, Hua

“…Porous polycaprolactone (PCL)/hydroxyapatite (HA) composite coatings are deposited via suspension flame spraying for marine ecological remediation. The…”
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Novel 6-amino-1,3,5-triazine derivatives as potent BTK inhibitors: structure-activity relationship (SAR) analysis and preliminary mechanism investigation by Xiao, Maoxu, Zhu, Meiqi, Wu, Shuangjie, Ma, Luyu, Qi, Lin, Ha, Si, Xiong, Shuangshuang, Chen, Mingqi, Chen, Deying, Luo, Guoshun, Xiang, Hua

“…[Display omitted] •A series of Novel 6-amino-1,3,5-triazine scaffold-based BTK irreversible inhibitors.•Representative compound C11 potently blocked activation…”
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Meta-analysis of SIRT1 expression as a prognostic marker for overall survival in gastrointestinal cancer by Wu, Shuangjie, Jiang, Jinghui, Liu, Jun, Wang, Xinhai, Gan, Yu, Tang, Yifan

“…Sirtuin 1 (SIRT1), a well-characterized NAD -dependent histone deacetylase, is generally up-regulated in gastrointestinal cancers. However, the prognostic…”
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Effects of curcumin‐based photodynamic treatment combined with low‐temperature storage on shelf life and purine content of Litopenaeus vannamei by Wang, Zhiguang, Zeng, Qingqing, Wu, Shuangjie, Guo, Min, Li, Zhaojie, Xue, Yong, Xue, Changhu, Wang, Zhe, Tang, Qingjuan

“…In this study, the effects of photodynamic treatment on the shelf life and purine content of Litopenaeus vannamei under low‐temperature storage conditions were…”
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X-ray crystallography study and optimization of novel benzothiophene analogs as potent selective estrogen receptor covalent antagonists (SERCAs) with improved potency and safety profiles by Bai, Chengfeng, Lv, Yang, Xiong, Shuangshuang, Wu, Shuangjie, Qi, Lin, Ren, Shengnan, Zhu, Meiqi, Dong, Haijuan, Shen, Hongtao, Li, Zhaoxing, Zhu, Yinxue, Ye, Hui, Hao, Haiping, Xiao, Yibei, Xiang, Hua, Luo, Guoshun

“…[Display omitted] •Cocrystal structure of ERαY537S bound to 15b (PDB ID: 7WNV).•Intact Mass spectrometry-based validation for ERαC417S-39d.•Superior antitumor…”
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