Search Results - "Wu, Shenshen"
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CircPTK2 (hsa_circ_0005273) as a novel therapeutic target for metastatic colorectal cancer
Published in Molecular cancer (23-01-2020)“…As a novel class of noncoding RNAs, circRNAs have been recently identified to regulate tumorigenesis and aggressiveness. However, the function of circRNAs in…”
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NAT10 accelerates pulmonary fibrosis through N4-acetylated TGFB1-initiated epithelial-to-mesenchymal transition upon ambient fine particulate matter exposure
Published in Environmental pollution (1987) (01-04-2023)“…Exposure to ambient fine particulate matter (PM2.5) has been linked to a higher pulmonary fibrosis risk. Dysregulation of the epitranscriptome results in…”
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HER2-specific chimeric antigen receptor-T cells for targeted therapy of metastatic colorectal cancer
Published in Cell death & disease (27-11-2021)“…Chimeric antigen receptor (CAR) - T cell therapy is a new class of cellular immunotherapies, which has made great achievements in the treatment of malignant…”
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A pan-Zea genome map for enhancing maize improvement
Published in Genome Biology (23-08-2022)“…Abstract Background Maize ( Zea mays L.) is at the vanguard facing the upcoming breeding challenges. However, both a super pan-genome for the Zea genus and a…”
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Response mechanism of groundwater dynamics to Freeze–thaw process in seasonally frozen soil areas: A comprehensive analysis from site to regional scale
Published in Journal of hydrology (Amsterdam) (01-10-2023)“…•Integrated analysis of meteorological-soil-groundwater information based on two typical monitoring sites and the plain area of Jilin Province, China.•Reveals…”
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Prediction of COPD acute exacerbation in response to air pollution using exosomal circRNA profile and Machine learning
Published in Environment international (01-10-2022)“…Air pollution has been intensively associated with acute exacerbation in COPD patients. In this study, we characterize COPD acute exacerbation (aeCOPD) in…”
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Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrogenase genes
Published in Proceedings of the National Academy of Sciences - PNAS (07-11-2017)“…Chronic obstructive pulmonary disease (COPD) has been linked to particulate matter (PM) exposure. Using transcriptomic analysis, we demonstrate that diesel…”
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Activation of NLRP3 in microglia exacerbates diesel exhaust particles-induced impairment in learning and memory in mice
Published in Environment international (01-03-2020)“…•DEPs-induced neural disorders are triggered by sustained activation of microglia.•Inhibition of NLRP3 inflammasome activation ameliorates the neural…”
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Correction: CircPTK2 (hsa_circ_0005273) as a novel therapeutic target for metastatic colorectal cancer
Published in Molecular cancer (02-04-2024)Get full text
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MPO Promoter Polymorphism rs2333227 Enhances Malignant Phenotypes of Colorectal Cancer by Altering the Binding Affinity of AP-2α
Published in Cancer research (Chicago, Ill.) (15-05-2018)“…Myeloperoxidase ( ) promoter SNPs rs2243828 (-764T>C) and rs2333227 (G-463A) program malignant phenotypes by regulating transcriptional activity. In this…”
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ZEAMAP, a Comprehensive Database Adapted to the Maize Multi-Omics Era
Published in iScience (26-06-2020)“…As one of the most extensively cultivated crops, maize (Zea mays L.) has been extensively studied by researchers and breeders for over a century. With advances…”
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gcaPDA: a haplotype-resolved diploid assembler
Published in BMC bioinformatics (14-02-2022)“…Generating chromosome-scale haplotype resolved assembly is important for functional studies. However, current de novo assemblers are either haploid assemblers…”
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Chemotherapeutic Risk lncRNA-PVT1 SNP Sensitizes Metastatic Colorectal Cancer to FOLFOX Regimen
Published in Frontiers in oncology (31-03-2022)“…Recent studies have identified that long noncoding RNA (lncRNA) might affect the responses to anticancer drug treatment, including colorectal cancer (CRC)…”
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Epstein–Barr Virus‐Encoded MicroRNA‐BART18‐3p Promotes Colorectal Cancer Progression by Targeting De Novo Lipogenesis
Published in Advanced science (01-12-2022)“…The Epstein–Barr virus (EBV) genome encodes a cluster of 22 viral microRNAs, called miR‐BamHI‐A rightward transcripts (miR‐BARTs), which are shown to promote…”
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Probiotics Ameliorate Colon Epithelial Injury Induced by Ambient Ultrafine Particles Exposure
Published in Advanced science (01-09-2019)“…Diesel exhaust particles (DEPs) are common airborne ultrafine particles (UFPs); however, few studies have examined their effects on the gastrointestinal tract…”
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Suppression of PTPN6 exacerbates aluminum oxide nanoparticle-induced COPD-like lesions in mice through activation of STAT pathway
Published in Particle and fibre toxicology (12-12-2017)“…Inhaled nanoparticles can deposit in the deep lung where they interact with pulmonary cells. Despite numerous studies on pulmonary nanotoxicity, detailed…”
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Colonic Injuries Induced by Inhalational Exposure to Particulate‐Matter Air Pollution
Published in Advanced science (05-06-2019)“…Particulate matter (PM) exposure has been associated with intestinal disorders. Therefore, there is an urgent need to understand the precise molecular…”
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Efficacy and Safety of Ultrasonic Bone Curette‐assisted Dome‐like Laminoplasty in the Treatment of Cervical Ossification of Longitudinal Ligament
Published in Orthopaedic surgery (01-02-2021)“…Objective To assess the efficacy and safety of ultrasonic bone curette‐assisted dome‐like laminoplasty in the treatment of ossification of longitudinal…”
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Intervertebral Foramen Width Is an Important Factor in Deciding Additional Uncinate Process Resection in ACDF—a Retrospective Study
Published in Frontiers in surgery (19-11-2021)“…Background: Anterior cervical discectomy and fusion (ACDF) has been established as a classic procedure for the management of cervical radiculopathy. However,…”
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