Search Results - "Wu, Shan‐Ying"

Degradative autophagy selectively regulates CCND1 (cyclin D1) and MIR224, two oncogenic factors involved in hepatocellular carcinoma tumorigenesis by Wu, Shan-Ying, Lan, Sheng-Hui, Liu, Hsiao-Sheng

“…Overexpressed CCND1 (cyclin D1) is associated with hepatocellular carcinoma (HCC) and we used 147 tumor tissue samples from HCC patients and 3 murine models to…”
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Hepatocellular carcinoma–related cyclin D1 is selectively regulated by autophagy degradation system by Wu, Shan‐Ying, Lan, Sheng‐Hui, Wu, Shang‐Rung, Chiu, Yen‐Chi, Lin, Xi‐Zhang, Su, Ih‐Jen, Tsai, Ting‐Fen, Yen, Chia‐Jui, Lu, Tsung‐Hsueh, Liang, Fu‐Wen, Li, Chung‐Yi, Su, Huey‐Jen, Su, Chun‐Li, Liu, Hsiao‐Sheng

“…Dysfunction of degradation machineries causes cancers, including hepatocellular carcinoma (HCC). Overexpression of cyclin D1 in HCC has been reported. We…”
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Autophagy suppresses tumorigenesis of hepatitis B virus‐associated hepatocellular carcinoma through degradation of microRNA‐224 by Lan, Sheng‐Hui, Wu, Shan‐Ying, Zuchini, Roberto, Lin, Xi‐Zhang, Su, Ih‐Jen, Tsai, Ting‐Fen, Lin, Yen‐Ju, Wu, Cheng‐Tao, Liu, Hsiao‐Sheng

“…In hepatocellular carcinoma (HCC), dysregulated expression of microRNA‐224 (miR‐224) and impaired autophagy have been reported separately. However, the…”
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Saponin Formosanin C-Induced Ferritinophagy and Ferroptosis in Human Hepatocellular Carcinoma Cells by Lin, Pin-Lun, Tang, Han-Hsuan, Wu, Shan-Ying, Shaw, Ning-Sing, Su, Chun-Li

“…Ferroptosis, a recently discovered form of iron-dependent cell death, requires an increased level of lipid-reactive oxygen species (ROS). Ferritinophagy, a…”
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Secretory autophagy promotes Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 by Wu, Shan-Ying, Chen, Jia-Wen, Liu, Hsi-Yu, Wang, Yi-Ching, Chu, Yeh-Shiu, Huang, Chi-Ying, Lan, Kai-Ying, Liu, Hsiao-Sheng, Lan, Sheng-Hui

“…Abstract Background Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 (TIMP1), an inflammatory cytokine, under serum-depleted conditions…”
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Formosanin C suppresses cancer cell proliferation and migration by impeding autophagy machinery by Chu, Man‐Ling, Lin, Pei‐Wen, Liu, Yu‐Wen, Wu, Shan‐Ying, Lan, Sheng‐Hui, Su, Chun‐Li, Liu, Hsiao‐Sheng

“…Formosanin C (FC) is a natural compound extracted from Paris formosana Hayata with anticancer activity. FC induces both autophagy and apoptosis in human lung…”
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Depression and self-care maintenance in patients with heart failure: A moderated mediation model of self-care confidence and resilience by Chang, Ling-Yin, Wu, Shan-Ying, Chiang, Chern-En, Tsai, Pei-Shan

“…Background: Despite the recognition of the negative effects of depressive symptoms on self-care confidence and self-care maintenance in patients with heart…”
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Regulation of autophagy, glucose uptake, and glycolysis under dengue virus infection by Lee, Ying‐Ray, Wu, Shan‐Ying, Chen, Ruei‐Yi, Lin, Yee‐Shin, Yeh, Trai‐Ming, Liu, Hsiao‐Sheng

“…We previously reported that dengue virus (DENV)‐induced autophagy plays a promoting role in viral replication and pathogenesis both in vitro and in vivo…”
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The role of Atg5 gene in tumorigenesis under autophagy deficiency conditions by Liu, Hsiao‐Sheng, Wang, Yin‐Ping, Lin, Pei‐Wen, Chu, Man‐Ling, Lan, Sheng‐Hui, Wu, Shan‐Ying, Lee, Ying‐Ray, Chang, Hong‐Yi

“…Autophagy is a self‐recycling machinery to maintain cellular homeostasis by degrading harmful materials in the cell. Autophagy‐related gene 5 (Atg5) is…”
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The Autophagosomes Containing Dengue Virus Proteins and Full-Length Genomic RNA Are Infectious by Wu, Shan-Ying, Chen, Yu-Lun, Lee, Ying-Ray, Lin, Chiou-Feng, Lan, Sheng-Hui, Lan, Kai-Ying, Chu, Man-Ling, Lin, Pei-Wen, Yang, Zong-Lin, Chen, Yen-Hsu, Wang, Wen-Hung, Liu, Hsiao-Sheng

“…Autophagic machinery is involved in selective and non-selective recruitment as well as degradation or exocytosis of cargoes, including pathogens. Dengue virus…”
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Vulnerability of Triple-Negative Breast Cancer to Saponin Formosanin C-Induced Ferroptosis by Chen, Hsin-Chih, Tang, Han-Hsuan, Hsu, Wei-Hsiang, Wu, Shan-Ying, Cheng, Wen-Hsing, Wang, Bao-Yuan, Su, Chun-Li

“…Targeting ferritin via autophagy (ferritinophagy) to induce ferroptosis, an iron- and reactive oxygen species (ROS)-dependent cell death, provides novel…”
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Autophagy Upregulates miR-449a Expression to Suppress Progression of Colorectal Cancer by Lan, Sheng-Hui, Lin, Shu-Ching, Wang, Wei-Chen, Yang, Yu-Chan, Lee, Jenq-Chang, Lin, Pei-Wen, Chu, Man-Ling, Lan, Kai-Ying, Zuchini, Roberto, Liu, Hsiao-Sheng, Wu, Shan-Ying

“…Many studies reported that microRNAs (miRNAs) target autophagy-related genes to affect carcinogenesis, however, autophagy-deficiency-related miRNA dysfunction…”
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Justicidin A-Induced Autophagy Flux Enhances Apoptosis of Human Colorectal Cancer Cells via Class III PI3K and Atg5 Pathway by Won, Shen-Jeu, Yen, Cheng-Hsin, Liu, Hsiao-Sheng, Wu, Shan-Ying, Lan, Sheng-Hui, Jiang-Shieh, Ya-Fen, Lin, Chun-Nan, Su, Chun-Li

“…Our previous reports showed that justicidin A (JA), a novel and pure arylnaphthalide lignan isolated from Justicia procumbens, induces apoptosis of human…”
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Arsenic treatment increase Aurora-A overexpression through E2F1 activation in bladder cells by Kao, Yu-Ting, Wu, Chin-Han, Wu, Shan-Ying, Lan, Sheng-Hui, Liu, Hsiao-Sheng, Tseng, Ya-Shih

“…Arsenic is a widely distributed metalloid compound that has biphasic effects on cultured cells. In large doses, arsenic can be toxic enough to trigger cell…”
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Ras-Related Tumorigenesis Is Suppressed by BNIP3-Mediated Autophagy through Inhibition of Cell Proliferation by Wu, Shan-Ying, Lan, Sheng-Hui, Cheng, Da-En, Chen, Wei-Kai, Shen, Cheng-Huang, Lee, Ying-Ray, Zuchini, Roberto, Liu, Hsiao-Sheng

“…Abstract Autophagy plays diverse roles in Ras-related tumorigenesis. H- rasval12 induces autophagy through multiple signaling pathways including Raf-1/ERK…”
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Pterostilbene Sensitizes Cisplatin-Resistant Human Bladder Cancer Cells with Oncogenic HRAS by Chen, Yi-Ting, Huang, Zi-Yi, Tang, Han-Hsuan, Kuo, Wan-Ting, Wu, Shan-Ying, Lan, Sheng-Hui, Chang, Kai-Hsun, Lin, Pin-Lun, Lee, Ming-Fen, Cheng, Hung-Chi, Liu, Hsiao-Sheng, Huang, Chi-Ying F., Huang, Guan-Cheng, Su, Chun-Li

“…Analysis of various public databases revealed that HRAS gene mutation frequency and mRNA expression are higher in bladder urothelial carcinoma. Further…”
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Induction of apoptotic death by curcumin in human tongue squamous cell carcinoma SCC-4 cells is mediated through endoplasmic reticulum stress and mitochondria-dependent pathways by Ip, Siu-Wan, Wu, Shan-Ying, Yu, Chien-Chih, Kuo, Chao-Lin, Yu, Chun-Shu, Yang, Jai-Sing, Lin, Zen-Pin, Chiou, Shang-Ming, Chung, Hsiung-Kwang, Ho, Heng-Chien, Chung, Jing-Gung

“…Curcumin from the rhizome of the Curcuma longa plant has been noted for its chemo‐preventative and chemo‐therapy activities, and it inhibits the growth of many…”
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Degradative autophagy regulates the homeostasis of miRnas to control cancer development by Wu, Shan-Ying, Chu, Chien-An, Lan, Sheng-Hui, Liu, Hsiao-Sheng

“…Macroautophagy/autophagy acts as an anti-tumor mechanism in early cancer stages but promotes growth in established tumors. Similarly, miRNAs function as tumor…”
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Secretory autophagy-promoted cargo exocytosis requires active RAB37 by Wu, Shan-Ying, Wang, Yi-Ching, Zuchini, Roberto, Lan, Kai-Ying, Liu, Hsiao-Sheng, Lan, Sheng-Hui

“…RAB37 GTPase regulates cargo exocytosis by cycling between an inactive GDP-bound form and an active GTP-bound form. We reveal that RAB37 simultaneously…”
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Autophagy and microRNA in hepatitis B virus-related hepatocellular carcinoma by Wu, Shan-Ying, Lan, Sheng-Hui, Liu, Hsiao-Sheng

“…Approximately 350 million people worldwide are chronically infected by hepatitis B virus (HBV). HBV causes severe liver diseases including cirrhosis and…”
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