Search Results - "Wu, Ryan T.Y."

Nutritional and supranutritional levels of selenate differentially suppress prostate tumor growth in adult but not young nude mice by Holmstrom, Alexandra, Wu, Ryan, T.Y, Zeng, Huawei, Lei, K.Y, Cheng, Wen-Hsing

“…The inhibitory effect of oral methylseleninic acid or methylselenocysteine administration on cancer cell xenograft development in nude mice is well…”
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Role for p53 in Selenium-Induced Senescence by Wu, Min, Wu, Ryan T. Y, Wang, Thomas T. Y, Cheng, Wen-Hsing

“…The tumor suppressor p53 and the ataxia-telangiectasia mutated (ATM) kinase play important roles in the senescence response to oncogene activation and DNA…”
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Effect of Sex on the Selenotranscriptomic Changes by Long‐term Dietary Selenium Deprivation and Aging in Short Telomere Mice by Cao, Lei, Wu, Ryan T.Y., Cheng, Wen‐Hsing

“…Abstract only Male Terc −/− short telomere mice on a diet deficient in selenium (Se) and during the aging process show selenotranscriptomic changes in a…”
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Sex Differences in the Responses of Gut Microbiome to Long‐term Dietary Selenium Deprivation and Aging in Short Telomere Mice by Lu, Hsin‐Yi, Wu, Ryan T.Y., Cheng, Wen‐Hsing

“…Abstract only How sex, dietary selenium (Se) and aging interact and affect mammalian gut microbiome is not known. Here, we sequenced bacterial 16S ribosomal…”
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Selenoprotein H Suppresses Cellular Senescence through Genome Maintenance and Redox Regulation by Wu, Ryan T.Y., Cao, Lei, Chen, Benjamin P.C., Cheng, Wen-Hsing

“…Oxidative stress and persistent DNA damage response contribute to cellular senescence, a degeneration process critically involving ataxia…”
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Sonic hedgehog pathway activation increases mitochondrial abundance and activity in hippocampal neurons by Yao, Pamela J, Manor, Uri, Petralia, Ronald S, Brose, Rebecca D, Wu, Ryan T Y, Ott, Carolyn, Wang, Ya-Xian, Charnoff, Ari, Lippincott-Schwartz, Jennifer, Mattson, Mark P

“…Mitochondria are essential organelles whose biogenesis, structure, and function are regulated by many signaling pathways. We present evidence that, in…”
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Selenoprotein H suppresses cellular senescence through genome maintenance and redox regulation by Wu, Ryan T.Y., Mattson, Elliot, Cheng, Wen‐Hsing

“…Abstract only Oxidative stress and persistent DNA damage can lead to cellular senescence and aging. Selenoprotein H (SelH) is known to carry redox domains and…”
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Loss of Selenium-Binding Protein 1 Decreases Sensitivity to Clastogens and Intracellular Selenium Content in HeLa Cells by Zhao, Changhui, Zeng, Huawei, Wu, Ryan T Y, Cheng, Wen-Hsing

“…Selenium-binding protein 1 (SBP1) is not a selenoprotein but structurally binds selenium. Loss of SBP1 during carcinogenesis usually predicts poor prognosis…”
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Selenoprotein H protects against oxidative DNA damage in the nucleus by Wu, Ryan T.Y., Wang, Thomas T.Y., Cheng, Wen‐Hsing

“…Selenoprotein H (SelH), a newly identified selenoprotein, is a nuclear protein known to protect cancer and neuronal cells from oxidative stress and radiation…”
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Critical roles of p53 and p16 in selenium‐induced senescence by Wu, Min, Wang, Thomas T.Y., Wu, Ryan T.Y., Cheng, Wen‐Hsing

“…We have reported recently that selenium compounds can induce an ATM‐dependent senescence response that depends on reactive oxygen species in normal pulmonary…”
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Effect of dietary selenium on T cell immunity and cancer xenograft in nude mice by Holmstrom, Alexandra, Li, Xiangdong, Wu, Ryan T.Y., Xiao, Zhengguo, Zeng, Huawei, Lei, K.Y., Cheng, Wen‐Hsing

“…Selenium is known to regulate carcinogenesis and immunity at nutritional and supranutritional levels. Because the immune system provides one of the main body…”
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Targeting Werner syndrome protein sensitizes U-2 OS osteosarcoma cells to selenium-induced DNA damage response and necrotic death by Cheng, Wen-Hsing, Wu, Ryan T.Y., Wu, Min, Rocourt, Caroline R.B., Carrillo, Jose A., Song, Jiuzhou, Bohr, Christina T., Tzeng, Tiffany J.

“…► We investigate novel strategy improving selenium effect on cancer cytotoxicity. ► Werner syndrome protein facilitates the repair of selenium-induced DNA…”
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Effect of Dietary Selenium and Cancer Cell Xenograft on Peripheral T and B Lymphocytes in Adult Nude Mice by Cheng, Wen-Hsing, Holmstrom, Alexandra, Li, Xiangdong, Wu, Ryan T. Y., Zeng, Huawei, Xiao, Zhengguo

“…Selenium (Se) is known to regulate tumorigenesis and immunity at the nutritional and supranutritional levels. Because the immune system provides critical…”
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New insight into telomere maintenance by Wu, Ryan T Y, Cheng, Wen-Hsing

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