Search Results - "Wu, Runlong"
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Miniature two-photon microscopy for enlarged field-of-view, multi-plane and long-term brain imaging
Published in Nature methods (01-01-2021)“…We have developed a miniature two-photon microscope equipped with an axial scanning mechanism and a long-working-distance miniature objective to enable…”
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Fast high-resolution miniature two-photon microscopy for brain imaging in freely behaving mice
Published in Nature methods (01-07-2017)“…FHIRM-TPM is a miniature two-photon microscope capable of imaging fluorescently labeled neurons in the brains of freely behaving mice. It allows for imaging of…”
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An optimized acetylcholine sensor for monitoring in vivo cholinergic activity
Published in Nature methods (01-11-2020)“…The ability to directly measure acetylcholine (ACh) release is an essential step toward understanding its physiological function. Here we optimized the GRAB…”
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Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy
Published in Nature biotechnology (01-04-2022)“…A main determinant of the spatial resolution of live-cell super-resolution (SR) microscopes is the maximum photon flux that can be collected. To further…”
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Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition
Published in Neuron (Cambridge, Mass.) (02-02-2022)“…Social competition plays a pivotal role in determining individuals’ social status. While the dorsomedial prefrontal cortex (dmPFC) is essential in regulating…”
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Long-term, in toto live imaging of cardiomyocyte behaviour during mouse ventricle chamber formation at single-cell resolution
Published in Nature cell biology (01-03-2020)“…Mapping of the holistic cell behaviours sculpting the four-chambered mammalian heart has been a goal or previous studies, but so far only success in…”
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In vivo imaging of β-cell function reveals glucose-mediated heterogeneity of β-cell functional development
Published in eLife (29-01-2019)“…How pancreatic β-cells acquire function in vivo is a long-standing mystery due to the lack of technology to visualize β-cell function in living animals. Here,…”
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Publisher Correction: Miniature two-photon microscopy for enlarged field-of-view, multi-plane and long-term brain imaging
Published in Nature methods (01-02-2021)“…A Correction to this paper has been published: https://doi.org/10.1038/s41592-021-01066-x…”
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Non-Invasive Skin Imaging Assessment of Human Stress During Head-Down Bed Rest Using a Portable Handheld Two-Photon Microscope
Published in Frontiers in physiology (25-07-2022)“…Spaceflight presents a series of physiological and pathological challenges to astronauts resulting from ionizing radiation, microgravity, isolation, and other…”
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Lensed Fiber-Optic Two-Photon Endomicroscopy for Field-of-View Enhancement
Published in Photonics (01-03-2023)“…Two-photon endomicroscopy is a promising technique with the ability to achieve in situ imaging and diagnosis at subcellular resolution. The large field-of-view…”
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Angiorganoid: vitalizing the organoid with blood vessels
Published in Vascular biology (01-09-2022)“…The emergence of the organoid simulates the native organs and this mini organ offers an excellent platform for probing multicellular interaction, disease…”
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Robust hollow-fiber-pigtailed 930 nm femtosecond Nd:fiber laser for volumetric two-photon imaging
Published in Optics express (18-09-2017)Get full text
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Fast, long-term, super-resolution imaging with Hessian structured illumination microscopy
Published in Nature biotechnology (01-06-2018)“…An improved image reconstruction algorithm increases time resolution and maximal imaging time for super-resolution microscopy. To increase the temporal…”
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Millimeter field-of-view miniature two-photon microscopy for brain imaging in freely moving mice
Published in Optics express (25-09-2023)“…Development of miniature two-photon microscopy (m2PM) has made it possible to observe fine structure and activity of neurons in the brain of freely moving…”
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Miniature three-photon microscopy maximized for scattered fluorescence collection
Published in Nature methods (01-04-2023)“…In deep-tissue multiphoton microscopy, diffusion and scattering of fluorescent photons, rather than ballistic emanation from the focal point, have been a…”
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Miniature Two-Photon Microscopic Imaging Using Dielectric Metalens
Published in Nano letters (13-09-2023)“…Miniature two-photon microscopy has emerged as a powerful technique for investigating brain activity in freely moving animals. Ongoing research objectives…”
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Spiral scanning fiber-optic two-photon endomicroscopy with a double-cladding antiresonant fiber
Published in Optics express (20-12-2021)“…Two-photon endomicroscopy is an optical biopsy tool that satisfies clinical requirements for real-time subcellular-resolution imaging to assist pathological…”
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Miniature Fluorescence Microscopy for Imaging Brain Activity in Freely-Behaving Animals
Published in Neuroscience bulletin (01-10-2020)“…An ultimate goal of neuroscience is to decipher the principles underlying neuronal information processing at the molecular, cellular, circuit, and system…”
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Robust hollow-fiber-pigtailed 930 nm femtosecond Nd:fiber laser for volumetric two-photon imaging
Published in Optics express (18-09-2017)“…We demonstrate a robust high power 930 nm femtosecond Nd:fiber laser system with hollow-core photonic bandgap fiber (HC-PBGF) as the output delivery, which can…”
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Two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement
Published in Optics express (18-07-2022)“…We demonstrate a miniature fiber-optic two two-photon endomicroscopy with microsphere-spliced double-cladding antiresonant fiber for resolution enhancement. An…”
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