Search Results - "Wu, Ronghu"

Mass Spectrometry-Based Chemical and Enzymatic Methods for Global Analysis of Protein Glycosylation by Xiao, Haopeng, Suttapitugsakul, Suttipong, Sun, Fangxu, Wu, Ronghu

“…Conspectus Glycosylation is one of the most common protein modifications, and it is essential for mammalian cell survival. It often determines protein folding…”
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An enrichment method based on synergistic and reversible covalent interactions for large-scale analysis of glycoproteins by Xiao, Haopeng, Chen, Weixuan, Smeekens, Johanna M., Wu, Ronghu

“…Protein glycosylation is ubiquitous in biological systems and essential for cell survival. However, the heterogeneity of glycans and the low abundance of many…”
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Quantitative investigation of human cell surface N -glycoprotein dynamics by Xiao, Haopeng, Wu, Ronghu

“…Surface glycoproteins regulate nearly every extracellular event and they are dynamic for cells to adapt to the ever-changing extracellular environment. These…”
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A Chemoenzymatic Method Based on Easily Accessible Enzymes for Profiling Protein O‑GlcNAcylation by Xu, Senhan, Sun, Fangxu, Wu, Ronghu

“…O-GlcNAcylation has gradually been recognized as a critically important protein post-translational modification in mammalian cells. Besides regulation of gene…”
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An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome by Sun, Fangxu, Suttapitugsakul, Suttipong, Wu, Ronghu

“…The tyrosine residue of proteins participates in a wide range of activities including enzymatic catalysis, protein–protein interaction, and protein–ligand…”
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Enhancing Comprehensive Analysis of Secreted Glycoproteins from Cultured Cells without Serum Starvation by Suttapitugsakul, Suttipong, Tong, Ming, Sun, Fangxu, Wu, Ronghu

“…Glycoproteins secreted by cells play essential roles in the regulation of extracellular activities. Secreted glycoproteins are often reflective of cellular…”
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Effective Method for Accurate and Sensitive Quantitation of Rapid Changes of Newly Synthesized Proteins by Tong, Ming, Suttapitugsakul, Suttipong, Wu, Ronghu

“…Protein synthesis is quickly and tightly regulated in cells to adapt to the ever-changing extracellular and intracellular environment. Accurate quantitation of…”
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Spatial and temporal proteomics reveals the distinct distributions and dynamics of O-GlcNAcylated proteins by Xu, Senhan, Tong, Ming, Suttapitugsakul, Suttipong, Wu, Ronghu

“…Protein O-GlcNAcylation plays critical roles in many cellular events, and its dysregulation is related to multiple diseases. Integrating bioorthogonal…”
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Systematic analysis of the impact of phosphorylation and O-GlcNAcylation on protein subcellular localization by Xu, Senhan, Suttapitugsakul, Suttipong, Tong, Ming, Wu, Ronghu

“…The subcellular localization of proteins is critical for their functions in eukaryotic cells and is tightly correlated with protein modifications. Here, we…”
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Targeting cancer cell integrins using gold nanorods in photothermal therapy inhibits migration through affecting cytoskeletal proteins by Ali, Moustafa R. K., Wu, Yue, Tang, Yan, Xiao, Haopeng, Chen, Kuangcai, Han, Tiegang, Fang, Ning, Wu, Ronghu, El-Sayed, Mostafa A.

“…Metastasis is responsible for most cancer-related deaths, but the current clinical treatments are not effective. Recently, gold nanoparticles (AuNPs) were…”
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Comprehensive Analysis of Protein Glycation Reveals Its Potential Impacts on Protein Degradation and Gene Expression in Human Cells by Sun, Fangxu, Suttapitugsakul, Suttipong, Xiao, Haopeng, Wu, Ronghu

“…Glycation as a type of non-enzymatic protein modification is related to aging and chronic diseases, especially diabetes. Global analysis of protein glycation…”
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Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion by Nguyen, Doan C., Garimalla, Swetha, Xiao, Haopeng, Kyu, Shuya, Albizua, Igor, Galipeau, Jacques, Chiang, Kuang-Yueh, Waller, Edmund K., Wu, Ronghu, Gibson, Greg, Roberson, James, Lund, Frances E., Randall, Troy D., Sanz, Iñaki, Lee, F. Eun-Hyung

“…Human antibody-secreting cells (ASC) in peripheral blood are found after vaccination or infection but rapidly apoptose unless they migrate to the bone marrow…”
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A large-scale method to measure absolute protein phosphorylation stoichiometries by Wu, Ronghu, Haas, Wilhelm, Dephoure, Noah, Huttlin, Edward L, Zhai, Bo, Sowa, Mathew E, Gygi, Steven P

“…The functional role of protein phosphorylation is determined not just by whether a particular site is phosphorylated or not but also by the site's…”
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Correct Interpretation of Comprehensive Phosphorylation Dynamics Requires Normalization by Protein Expression Changes by Wu, Ronghu, Dephoure, Noah, Haas, Wilhelm, Huttlin, Edward L., Zhai, Bo, Sowa, Mathew E., Gygi, Steven P.

“…The interpretation of quantitative phosphoproteomics studies is complicated because each differential phosphorylation event integrates both changes in protein…”
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Protonation Sites and Conformations of Peptides of Glycine (Gly1−5H+) by IRMPD Spectroscopy by Wu, Ronghu, McMahon, Terry B

“…The protonation sites and conformations of protonated glycine and its peptides (Gly1−5) have been investigated using infrared multiple photon dossociation…”
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Infrared Multiple Photon Dissociation Spectra of Proline and Glycine Proton-Bound Homodimers. Evidence for Zwitterionic Structure by Wu, Ronghu, McMahon, Terry B

“…Infrared multiple photon dissociation (IRMPD) spectroscopy is a very powerful technique to characterize the structures of ions and ionic clusters. The…”
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An Investigation of Protonation Sites and Conformations of Protonated Amino Acids by IRMPD Spectroscopy by Wu, Ronghu, McMahon, Terry B.

“…The protonation sites and structures of a series of protonated amino acids (Gly, Ala, Pro, Phe, Lys and Ser) are investigated by means of infrared…”
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Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage by Lopez-Martinez, David, Kupculak, Marian, Yang, Di, Yoshikawa, Yasunaga, Liang, Chih-Chao, Wu, Ronghu, Gygi, Steven P, Cohn, Martin A

“…Interstrand crosslinks (ICLs) of the DNA helix are a deleterious form of DNA damage. ICLs can be repaired by the Fanconi anemia pathway. At the center of the…”
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Carfilzomib Treatment Causes Molecular and Functional Alterations of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Forghani, Parvin, Rashid, Aysha, Sun, Fangxu, Liu, Rui, Li, Dong, Lee, Megan R, Hwang, Hyun, Maxwell, Joshua T, Mandawat, Anant, Wu, Ronghu, Salaita, Khalid, Xu, Chunhui

“…Background Anticancer therapies have significantly improved patient outcomes; however, cardiac side effects from cancer therapies remain a significant…”
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Author Correction: Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion by Nguyen, Doan C., Garimalla, Swetha, Xiao, Haopeng, Kyu, Shuya, Albizua, Igor, Galipeau, Jacques, Chiang, Kuang-Yueh, Waller, Edmund K., Wu, Ronghu, Gibson, Greg, Roberson, James, Lund, Frances E., Randall, Troy D., Sanz, Iñaki, Lee, F. Eun-Hyung

“…The original version of this Article omitted a declaration from the Competing Interests statement, which should have included the following: ‘A patent has been…”
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