Search Results - "Wu, Qinjie"

Biodegradable and injectable in situ cross-linking chitosan-hyaluronic acid based hydrogels for postoperative adhesion prevention by Li, Ling, Wang, Ning, Jin, Xun, Deng, Rui, Nie, Shihong, Sun, Lu, Wu, Qinjie, Wei, Yuquan, Gong, Changyang

“…Abstract Postsurgical peritoneal adhesions are very common and serious complication after surgery. Biodegradable and injectable hydrogels derived from natural…”
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A cooperative nano-CRISPR scaffold potentiates immunotherapy via activation of tumour-intrinsic pyroptosis by Wang, Ning, Liu, Chao, Li, Yingjie, Huang, Dongxue, Wu, Xinyue, Kou, Xiaorong, Wang, Xiye, Wu, Qinjie, Gong, Changyang

“…Efficient cancer immunotherapy depends on selective targeting of high bioactivity therapeutic agents to the tumours. However, delivering exogenous medication…”
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Recent advances in enhancing reactive oxygen species based chemodynamic therapy by Li, Xinchao, Luo, Rui, Liang, Xiuqi, Wu, Qinjie, Gong, Changyang

“…Chemodynamic therapy (CDT), defined as an in situ oxidative stress response catalyzed by the Fenton or Fenton-like reactions to generate cytotoxic hydroxyl…”
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Artificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice by Li, Ling, Song, Linjiang, Liu, Xiaowei, Yang, Xi, Li, Xia, He, Tao, Wang, Ning, Yang, Suleixin, Yu, Chuan, Yin, Tao, Wen, Yanzhu, He, Zhiyao, Wei, Xiawei, Su, Weijun, Wu, Qinjie, Yao, Shaohua, Gong, Changyang, Wei, Yuquan

“…CRISPR-Cas9 has emerged as a versatile genome-editing platform. However, due to the large size of the commonly used CRISPR-Cas9 system, its effective delivery…”
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Improving antiangiogenesis and anti-tumor activity of curcumin by biodegradable polymeric micelles by Gong, Changyang, Deng, Senyi, Wu, Qinjie, Xiang, Mingli, Wei, Xiawei, Li, Ling, Gao, Xiang, Wang, Bilan, Sun, Lu, Chen, Yishan, Li, Yuchen, Liu, Lei, Qian, Zhiyong, Wei, Yuquan

“…Abstract For developing aqueous formulation and improving anti-tumor activity of curcumin (Cur), we prepared Cur encapsulated MPEG-PCL micelles by solid…”
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A spontaneously formed and self-adjuvanted hydrogel vaccine triggers strong immune responses by He, Tao, Liang, Xiuqi, Li, Lu, Gong, Songlin, Li, Xinchao, Zhang, Miaomiao, Zhu, Shunyao, Xiao, Haitao, Wu, Qinjie, Gong, Changyang

“…Hydrogel is a promising vaccine delivery vehicle, and have been applied to deliver antigens and adjuvants to enhance the immunogenicity of antigens. However,…”
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Curcumin-Encapsulated Polymeric Micelles Suppress the Development of Colon Cancer In Vitro and In Vivo by Yang, Xi, Li, Zhaojun, Wang, Ning, Li, Ling, Song, Linjiang, He, Tao, Sun, Lu, Wang, Zhihan, Wu, Qinjie, Luo, Na, Yi, Cheng, Gong, Changyang

“…To develop injectable formulation and improve the stability of curcumin (Cur), Cur was encapsulated into monomethyl poly (ethylene glycol)-poly…”
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Nanotechnology‐based CRISPR/Cas9 delivery system for genome editing in cancer treatment by Zhou, Shiyao, Li, Yingjie, Wu, Qinjie, Gong, Changyang

“…The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR associated protein 9 (CRISPR/Cas9) systems initiate a revolution in genome…”
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Gambogic acid-encapsulated polymeric micelles improved therapeutic effects on pancreatic cancer by Wang, Yan, Wang, Xinxin, Zhang, Jing, Wang, Li, Ou, Chunqing, Shu, Yaqian, Wu, Qinjie, Ma, Guolin, Gong, Changyang

“…Monomethyl poly(ethylene glycol)-poly(ε-caprolactone)-poly(trimethylene carbonate) (MPEG-P(CL-ran-TMC)) copolymer was synthesized, which could encapsulate GA…”
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A self-sustaining nanoplatform overcomes TRAIL-resistance of pancreatic cancer by a source-broadening and expenditure-reducing apoptosis strategy by Huang, Xianzhou, Li, Haijun, Ou, Chunqing, Shu, Yaqian, Luo, Rui, Li, Xinchao, Chen, Shouchun, Wu, Qinjie, Gong, Changyang, Liu, Lei

“…[Display omitted] •Death receptor on TRAIL-resistant pancreatic cancer was reversely upregulated by SSN.•The upregulation enhanced tumor cumulation of SSN,…”
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A multifunctional 'golden cicada' nanoplatform breaks the thermoresistance barrier to launch cascade augmented synergistic effects of photothermal/gene therapy by Yang, Wen, Wang, Ning, Yang, Jin, Liu, Chao, Ma, Shuang, Wang, Xiye, Li, Wenzhen, Shen, Meiling, Wu, Qinjie, Gong, Changyang

“…Photothermal therapy (PTT) is taken as a promising strategy for cancer therapy, however, its applicability is hampered by cellular thermoresistance of heat…”
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TRAIL and curcumin codelivery nanoparticles enhance TRAIL-induced apoptosis through upregulation of death receptors by Yang, Xi, Li, Zhaojun, Wu, Qinjie, Chen, Shouchun, Yi, Cheng, Gong, Changyang

“…Active targeting nanoparticles were developed to simultaneously codeliver tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Curcumin (Cur)…”
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Programmable Unlocking Nano‐Matryoshka‐CRISPR Precisely Reverses Immunosuppression to Unleash Cascade Amplified Adaptive Immune Response by Yang, Jin, Li, Zhike, Shen, Meiling, Wang, Yan, Wang, Li, Li, Jiamiao, Yang, Wen, Li, Jie, Li, Haijun, Wang, Xinxin, Wu, Qinjie, Gong, Changyang

“…Immune checkpoint blockade (ICB) is an attractive option in cancer therapy, but its efficacy is still less than expected due to the transient and incomplete…”
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Novel polyethyleneimine-R8-heparin nanogel for high-efficiency gene delivery in vitro and in vivo by Song, Linjiang, Liang, Xiuqi, Yang, Suleixin, Wang, Ning, He, Tao, Wang, Yan, Zhang, Lan, Wu, Qinjie, Gong, Changyang

“…Gene therapy is an efficient and promising approach to treat malignant tumors. However, protecting the nucleic acid from degradation in vivo and efficient…”
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Author Correction: Inhibition of A20 expression in tumor microenvironment exerts anti-tumor effect through inducing myeloid-derived suppressor cells apoptosis by Shao, Bin, Wei, Xiawei, Luo, Min, Yu, Jiayun, Tong, Aiping, Ma, Xuelei, Ye, Tinghong, Deng, Hongxin, Sang, Yaxiong, Liang, Xiao, Ma, Yu, Wu, Qinjie, Du, Wei, Du, Jing, Gao, Xiang, Wen, Yi, Fu, Ping, Shi, Huashan, Luo, Shuntao, Wei, Yuquan

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A self-assembly reproducible nanoplatform enables cancer phenotypic lethality in solid tumors by Yang, Xi, Gao, Ling, Wang, Ning, Li, Yongjiang, Song, Linjiang, He, Tao, Zhang, Wenli, Yi, Cheng, He, Gu, Wu, Qinjie, Gong, Changyang

“…The self-assembly reproducible nanoplatform (SRNA) could efficiently silence MutT Homolog1 (MTH1) expression and accumulated oxidized deoxynucleoside…”
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Self-sufficient nanoparticles with dual-enzyme activity trigger radical storms and activate cascade-amplified antitumor immunologic responses by Bai, Liping, Yang, Jin, Yu, Siting, Xiang, Zhongzheng, Zeng, Yuanyuan, Shen, Meiling, Kou, Xiaorong, Wu, Qinjie, Gong, Changyang

“…Radiotherapy (RT) can potentially induce systemic immune responses by initiating immunogenic cell death (ICD) of tumor cells. However, RT-induced antitumor…”
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Improving Anti-Tumor Activity of Curcumin by Polymeric Micelles in Thermosensitive Hydrogel System in Colorectal Peritoneal Carcinomatosis Model by Zhang, Wenli, Cui, Tao, Liu, Lei, Wu, Qinjie, Sun, Lu, Li, Ling, Wang, Ning, Gong, Changyang

“…In this work, we prepared an in situ gel-forming composite drug delivery system (DDS) to treat colorectal peritoneal carcinomatosis. The composite DDS was…”
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Thermosensitive hydrogel containing dexamethasone micelles for preventing postsurgical adhesion in a repeated-injury model by Wu, Qinjie, Wang, Ning, He, Tao, Shang, Jinfeng, Li, Ling, Song, Linjiang, Yang, Xi, Li, Xia, Luo, Na, Zhang, Wenli, Gong, Changyang

“…Tissue adhesion is a common complication after surgery. In this work, a dexamethasone loaded polymeric micelles in thermosensitive hydrogel composite (Dex…”
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A tactical nanomissile mobilizing antitumor immunity enables neoadjuvant chemo-immunotherapy to minimize postsurgical tumor metastasis and recurrence by He, Tao, Hu, Mingxing, Zhu, Shunyao, Shen, Meiling, Kou, Xiaorong, Liang, Xiuqi, Li, Lu, Li, Xinchao, Zhang, Miaomiao, Wu, Qinjie, Gong, Changyang

“…Neoadjuvant chemotherapy has become an indispensable weapon against high-risk resectable cancers, which benefits from tumor downstaging. However, the utility…”
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