Search Results - "Wu, Lisa Y"

Capture and Visualization of Hydrogen Sulfide by a Fluorescent Probe by Liu, Chunrong, Pan, Jia, Li, Sheng, Zhao, Yu, Wu, Lisa Y., Berkman, Clifford E., Whorton, A. Richard, Xian, Ming

“…Reaction‐based sensing: A fluorescent probe for the detection of hydrogen sulfide was prepared and evaluated on the basis of H2S‐mediated benzodithiolone…”
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Cell-Surface labeling and internalization by a fluorescent inhibitor of prostate-specific membrane antigen by Liu, Tiancheng, Wu, Lisa Y., Kazak, Marat, Berkman, Clifford E.

“…BACKROUND Prostate‐specific membrane antigen (PSMA) remains an attractive target for imaging and therapeutic applications for prostate cancer. Recent efforts…”
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A targeted low molecular weight near-infrared fluorescent probe for prostate cancer by Liu, Tiancheng, Wu, Lisa Y., Hopkins, Mark R., Choi, Joseph K., Berkman, Clifford E.

“…A novel near-infrared imaging probe was synthesized, which exhibited potent PSMA inhibitory activity (IC 50 = 0.55 nM) and PSMA-targeted imaging of prostate…”
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Prostate-specific membrane antigen-targeted photodynamic therapy induces rapid cytoskeletal disruption by Liu, Tiancheng, Wu, Lisa Y, Berkman, Clifford E

“…Abstract Prostate-specific membrane antigen (PSMA), an established enzyme–biomarker for prostate cancer, has attracted considerable attention as a target for…”
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Substrate specificity of prostate-specific membrane antigen by Anderson, Marc O., Wu, Lisa Y., Santiago, Nicholas M., Moser, Jamie M., Rowley, Jennifer A., Bolstad, Erin S.D., Berkman, Clifford E.

“…A series of potential PSMA substrates was prepared that explored acidic residues at the P1 position and various chromophores at the P2 position, while keeping…”
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In vitro targeted photodynamic therapy with a pyropheophorbide-a conjugated inhibitor of prostate-specific membrane antigen by Liu, Tiancheng, Wu, Lisa Y., Choi, Joseph K., Berkman, Clifford E.

“…BACKGROUND The lack of specific delivery of photosensitizers (PSs), represents a significant limitation of photodynamic therapy (PDT) of cancer. The biomarker…”
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Targeting prostate cancer cells with a multivalent PSMA inhibitor-guided streptavidin conjugate by Liu, Tiancheng, Nedrow-Byers, Jessie R., Hopkins, Mark R., Wu, Lisa Y., Lee, Jeonghoon, Reilly, Peter T.A., Berkman, Clifford E.

“…A series of spacer-varied biotinylated PSMA inhibitors were synthesized and evaluated, which exhibited spacer length-dependent effects on inhibitory potency,…”
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The molecular pruning of a phosphoramidate peptidomimetic inhibitor of prostate-specific membrane antigen by Wu, Lisa Y., Anderson, Marc O., Toriyabe, Yoko, Maung, Jack, Campbell, Tammy Y., Tajon, Cheryl, Kazak, Marat, Moser, Jamie, Berkman, Clifford E.

“…To identify the pharmacophore of a phosphoramidate peptidomimetic inhibitor of prostate-specific membrane antigen (PSMA), a small analog library was designed…”
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Biochemical characterization of prostate-specific membrane antigen from canine prostate carcinoma cells by Wu, Lisa Y., Johnson, Jacqueline M., Simmons, Jessica K., Mendes, Desiree E., Geruntho, Jonathan J., Liu, Tiancheng, Dirksen, Wessel P., Rosol, Thomas J., Davis, William C., Berkman, Clifford E.

“…BACKGROUND Prostate‐specific membrane antigen (PSMA) remains an important target for diagnostic and therapeutic application for human prostate cancer. Model…”
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Flow cytometric detection of prostate tumor cells using chemoaffinity labels by Wu, Lisa Y., Liu, Tiancheng, Grimm, Amanda L., Davis, William C., Berkman, Clifford E.

“…BACKGROUND The enzyme‐biomarker prostate‐specific membrane antigen (PSMA) is an emerging target for imaging and therapeutic applications for prostate cancer…”
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Prolonged androgen deprivation leads to downregulation of androgen receptor and prostate-specific membrane antigen in prostate cancer cells by LIU, TIANCHENG, WU, LISA Y, FULTON, MELODY D, JOHNSON, JACQUELINE M, BERKMAN, CLIFFORD E

“…Emergence of androgen-independent cancer cells during androgen deprivation therapy presents a significant challenge to successful treatment outcomes in…”
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Targeted photodynamic therapy for prostate cancer: Inducing apoptosis via activation of the caspase-8/-3 cascade pathway by TIANCHENG LIU, WU, Lisa Y, CHOI, Joseph K, BERKMAN, Clifford E

“…The limitation of specific delivery of photosensitizers to tumor sites, represents a significant shortcoming of photodynamic therapy (PDT) application at…”
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Detection of prostate-specific membrane antigen on HUVECs in response to breast tumor-conditioned medium by TIANCHENG LIU, JABBES, Mohamed, NEDROW-BYERS, Jessie R, WU, Lisa Y, BRYAN, Jeffrey N, BERKMAN, Clifford E

“…Prostate-specific membrane antigen (PSMA), a well-known biomarker of prostate cancer, has also been found to be highly expressed in the neovasculature of…”
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Assessment of an 18F-Labeled Phosphoramidate Peptidomimetic as a New Prostate-Specific Membrane Antigen-Targeted Imaging Agent for Prostate Cancer by Lapi, Suzanne E, Wahnishe, Hilla, Pham, David, Wu, Lisa Y, Nedrow-Byers, Jessie R, Liu, Tiancheng, Vejdani, Kaveh, VanBrocklin, Henry F, Berkman, Clifford E, Jones, Ella F

“…Prostate-specific membrane antigen (PSMA) is a transmembrane protein commonly found on the surface of late-stage and metastatic prostate cancer and a…”
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Chemoaffinity capture of pre-targeted prostate cancer cells with magnetic beads by Wu, Lisa Y., Liu, Tiancheng, Hopkins, Mark R., Davis, William C., Berkman, Clifford E.

“…BACKROUND Prostate circulating tumor cells (PCTCs) in circulation are shed from either a primary tumor or metastases, which are directly responsible for most…”
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Capture and Visualization of Hydrogen Sulfide by a Fluorescent Probe by Liu, Chunrong, Pan, Jia, Li, Sheng, Zhao, Yu, Wu, Lisa Y., Berkman, Clifford E., Whorton, A. Richard, Xian, Ming

“…Reaktionsbasierter Nachweis: Eine Fluoreszenzsonde für den Nachweis von Schwefelwasserstoff wurde auf Basis der H2S‐vermittelten Bildung von Benzodithiolon…”
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Probing for a hydrophobic a binding register in prostate-specific membrane antigen with phenylalkylphosphonamidates by Maung, Jack, Mallari, Jeremy P., Girtsman, Teri A., Wu, Lisa Y., Rowley, Jennifer A., Santiago, Nicholas M., Brunelle, Alan N., Berkman, Clifford E.

“…A series of phenylalkylphosphonamidate derivatives of glutamic acid were synthesized and evaluated for their inhibitory potencies against PSMA. The greatest…”
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Phosphoramidate derivatives of hydroxysteroids as inhibitors of prostate-specific membrane antigen by Wu, Lisa Y., Do, Jacinda C., Kazak, Marat, Page, Helen, Toriyabe, Yoko, Anderson, Marc O., Berkman, Clifford E.

“…Prostate-specific membrane antigen (PSMA) is a membrane-bound cell surface peptidase which is over-expressed in prostate cancer cells. The enzymatic activities…”
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Capture and Visualization of Hydrogen Sulfide by a Fluorescent Probe by Liu, Chunrong, Pan, Jia, Li, Sheng, Zhao, Yu, Wu, Lisa Y., Berkman, Clifford E., Whorton, A. Richard, Xian, Ming

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Abstract 214: Androgen resistance in prostate cancer is associated with an enrichment of stem-like cells by Wu, Lisa Y., Bansal, Nitu, Liu, Tiancheng, Berkman, Clifford E., Bertino, Joseph R.

“…Abstract Cancer Stem cells (CSCs) or tumor initiating cells (TICs) have recently been identified in solid tumors; however, the role of CSCs/TICs in metastasis…”
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