Search Results - "Wu, Keliang"
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Synthesis of cellulose-based double-network hydrogels demonstrating high strength, self-healing, and antibacterial properties
Published in Carbohydrate polymers (15-07-2017)“…•A novel double network hydrogel with superior mechanical property was prepared.•The prepared hydrogel maintained good self-healing properties.•The hydrogel…”
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Clinical outcomes following frozen-thawed blastocyst transfers with blastocysts derived from different cell numbers on day 3: a retrospective cohort study
Published in Journal of assisted reproduction and genetics (01-03-2020)“…Purpose To evaluate clinical outcomes after frozen-thawed blastocyst transfer (TBT) with blastocysts which were derived from different cell numbers on day 3…”
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Tild-CRISPR Allows for Efficient and Precise Gene Knockin in Mouse and Human Cells
Published in Developmental cell (21-05-2018)“…The targeting efficiency of knockin sequences via homologous recombination (HR) is generally low. Here we describe a method we call Tild-CRISPR (targeted…”
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A Recurrent Missense Mutation in ZP3 Causes Empty Follicle Syndrome and Female Infertility
Published in American journal of human genetics (07-09-2017)“…Empty follicle syndrome (EFS) is defined as the failure to aspirate oocytes from mature ovarian follicles during in vitro fertilization. Except for some cases…”
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Translatome and transcriptome co-profiling reveals a role of TPRXs in human zygotic genome activation
Published in Science (American Association for the Advancement of Science) (07-10-2022)“…Translational regulation plays a critical role during the oocyte-to-embryo transition (OET) and zygotic genome activation (ZGA). Here, we integrated…”
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Single-cell transcriptome and translatome dual-omics reveals potential mechanisms of human oocyte maturation
Published in Nature communications (30-08-2022)“…The combined use of transcriptome and translatome as indicators of gene expression profiles is usually more accurate than the use of transcriptomes alone,…”
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A unique 15-bp InDel in the first intron of BMPR1B regulates its expression in Taihu pigs
Published in BMC genomics (03-12-2022)“…BMPR1B (Bone morphogenetic protein receptor type-1B) is a receptor in the bone morphogenetic protein (BMP) family and has been identified as a candidate gene…”
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An Integrative ATAC-Seq and RNA-Seq Analysis of the Endometrial Tissues of Meishan and Duroc Pigs
Published in International journal of molecular sciences (01-10-2023)“…Meishan pigs are a well-known indigenous pig breed in China characterized by a high fertility. Notably, the number of endometrial grands is significantly…”
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Human embryo polarization requires PLC signaling to mediate trophectoderm specification
Published in eLife (27-09-2021)“…Apico-basal polarization of cells within the embryo is critical for the segregation of distinct lineages during mammalian development. Polarized cells become…”
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Synthesis of layered compound from walnut shell by template method TiO2/CdS/CoP application of photocatalyst in efficient hydrogen productions
Published in Applied physics. A, Materials science & processing (01-12-2021)“…The photocatalytic H 2 production requires catalysts with specific and optimized crystal morphology, surface area and interfacial bonding. In this work, we…”
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TGF-Beta Induced Key Genes of Osteogenic and Adipogenic Differentiation in Human Mesenchymal Stem Cells and MiRNA-mRNA Regulatory Networks
Published in Frontiers in genetics (25-11-2021)“…The clinical efficacy of osteoporosis therapy is unsatisfactory. However, there is currently no gold standard for the treatment of osteoporosis. Recent studies…”
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Design of a Z-scheme printable artificial leaf device based on CdS@TiO2/Pt/ITO/WO3@Co3O4 for water splitting
Published in Applied physics. A, Materials science & processing (2022)“…Hydrogen and oxygen production based on photocatalytic monolithic water splitting is considered to be one of the effective ways to produce sustainable and…”
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TiO2 nanotubes/g-C3N4 quantum dots/rGO Schottky heterojunction nanocomposites as sensors for ppb-level detection of NO2
Published in Journal of materials science (01-05-2019)“…As a strong oxidizing pollutant, NO 2 can cause fire or even explosion. People living in atmosphere containing NO 2 for a long time will significantly affects…”
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Melatonin promotes human oocyte maturation and early embryo development by enhancing clathrin‐mediated endocytosis
Published in Journal of pineal research (01-10-2019)“…Embryo development potential and reproductive clinical outcomes are all deeply rooted in oocyte maturation. Melatonin has been reported to promote oocyte…”
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Comparison of clinical outcomes of frozen-thawed D5 and D6 blastocysts undergoing preimplantation genetic testing
Published in Journal of translational medicine (26-11-2022)“…This study aimed to analyze the clinical outcomes of blastocyst which undergo the preimplantation genetic testing (PGT) transplantation from frozen-thawed D5…”
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Dominant mutations in CHK1 cause pronuclear fusion failure and zygote arrest that can be rescued by CHK1 inhibitor
Published in Cell research (01-07-2021)Get full text
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2-bromoacetamide exposure impairs oocyte maturation in mice and humans primarily via disrupting the cytoskeleton
Published in Ecotoxicology and environmental safety (01-03-2024)“…2-bromoacetamide (BAcAm) is an emerging class of unregulated disinfection by-products (DBPs), with potent cytogenetic and developmental toxicity in animals…”
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Artificial intelligence system for outcome evaluations of human in vitro fertilization-derived embryos
Published in Chinese medical journal (20-08-2024)“…In vitro fertilization (IVF) has emerged as a transformative solution for infertility. However, achieving favorable live-birth outcomes remains challenging…”
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Maternal mRNA deadenylation is defective in in vitro matured mouse and human oocytes
Published in Nature communications (02-07-2024)“…Oocyte in vitro maturation is a technique in assisted reproductive technology. Thousands of genes show abnormally high expression in in vitro maturated…”
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A newly identified small tRNA fragment reveals the regulation of different wool types and oxidative stress in lambs
Published in Scientific reports (23-06-2023)“…Novel small RNAs derived from tRNAs are continuously identified, however, their biological functions are rarely reported. Here, we accidentally found the reads…”
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