Search Results - "Wu, Julie Z."

Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production by Zhang, Shuling, Readinger, Julie A., DuBois, Wendy, Janka-Junttila, Mirkka, Robinson, Richard, Pruitt, Margaret, Bliskovsky, Val, Wu, Julie Z., Sakakibara, Kaori, Patel, Jyoti, Parent, Carole A., Tessarollo, Lino, Schwartzberg, Pamela L., Mock, Beverly A.

“…Mammalian TOR (mTOR) regulates cell growth, proliferation, and migration. Because mTOR knock-outs are embryonic lethal, we generated a viable hypomorphic mouse…”
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Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells by Gomez-Rodriguez, Julio, Wohlfert, Elizabeth A, Handon, Robin, Meylan, Françoise, Wu, Julie Z, Anderson, Stacie M, Kirby, Martha R, Belkaid, Yasmine, Schwartzberg, Pamela L

“…A proper balance between Th17 and T regulatory cells (Treg cells) is critical for generating protective immune responses while minimizing autoimmunity. We show…”
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Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation by Cannons, Jennifer L, Wu, Julie Z, Gomez-Rodriguez, Julio, Zhang, Jinyi, Dong, Baoxia, Liu, Yin, Shaw, Stephen, Siminovitch, Katherine A, Schwartzberg, Pamela L

“…Signaling lymphocytic activation molecule-associated protein (SAP), an adaptor molecule that recruits Fyn to the signaling lymphocytic activation molecule…”
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Biochemical and Genetic Evidence for a SAP-PKC-{theta} Interaction Contributing to IL-4 Regulation by Cannons, Jennifer L, Wu, Julie Z, Gomez-Rodriguez, Julio, Zhang, Jinyi, Dong, Baoxia, Liu, Yin, Shaw, Stephen, Siminovitch, Katherine A, Schwartzberg, Pamela L

“…Signaling lymphocytic activation molecule-associated protein (SAP), an adaptor molecule that recruits Fyn to the signaling lymphocytic activation molecule…”
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