Search Results - "Wu, Joshua H."

Mapping Development of the Human Intestinal Niche at Single-Cell Resolution by Holloway, Emily M., Czerwinski, Michael, Tsai, Yu-Hwai, Wu, Joshua H., Wu, Angeline, Childs, Charlie J., Walton, Katherine D., Sweet, Caden W., Yu, Qianhui, Glass, Ian, Treutlein, Barbara, Camp, J. Gray, Spence, Jason R.

“…The human intestinal stem cell niche supports self-renewal and epithelial function, but little is known about its development. We used single-cell mRNA…”
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R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development by Hein, Renee F.C., Wu, Joshua H., Holloway, Emily M., Frum, Tristan, Conchola, Ansley S., Tsai, Yu-Hwai, Wu, Angeline, Fine, Alexis S., Miller, Alyssa J., Szenker-Ravi, Emmanuelle, Yan, Kelley S., Kuo, Calvin J., Glass, Ian, Reversade, Bruno, Spence, Jason R.

“…The human respiratory epithelium is derived from a progenitor cell in the distal buds of the developing lung. These “bud tip progenitors” are regulated by…”
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EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids by Childs, Charlie J, Holloway, Emily M, Sweet, Caden W, Tsai, Yu-Hwai, Wu, Angeline, Vallie, Abigail, Eiken, Madeline K, Capeling, Meghan M, Zwick, Rachel K, Palikuqi, Brisa, Trentesaux, Coralie, Wu, Joshua H, Pellón-Cardenas, Oscar, Zhang, Charles J, Glass, Ian, Loebel, Claudia, Yu, Qianhui, Camp, J Gray, Sexton, Jonathan Z, Klein, Ophir D, Verzi, Michael P, Spence, Jason R

“…Epithelial organoids derived from intestinal tissue, called enteroids, recapitulate many aspects of the organ in vitro and can be used for biological…”
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Leaving flatland: Advances in 3D behavioral measurement by Marshall, Jesse D., Li, Tianqing, Wu, Joshua H., Dunn, Timothy W.

“…Animals move in three dimensions (3D). Thus, 3D measurement is necessary to report the true kinematics of animal movement. Existing 3D measurement techniques…”
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Differentiation of Human Intestinal Organoids with Endogenous Vascular Endothelial Cells by Holloway, Emily M., Wu, Joshua H., Czerwinski, Michael, Sweet, Caden W., Wu, Angeline, Tsai, Yu-Hwai, Huang, Sha, Stoddard, Amy E., Capeling, Meghan M., Glass, Ian, Spence, Jason R.

“…Human pluripotent stem cell (hPSC)-derived intestinal organoids (HIOs) lack some cellular populations found in the native organ, including vasculature. Using…”
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Charting human development using a multi-endodermal organ atlas and organoid models by Yu, Qianhui, Kilik, Umut, Holloway, Emily M., Tsai, Yu-Hwai, Harmel, Christoph, Wu, Angeline, Wu, Joshua H., Czerwinski, Michael, Childs, Charlie J., He, Zhisong, Capeling, Meghan M., Huang, Sha, Glass, Ian A., Higgins, Peter D.R., Treutlein, Barbara, Spence, Jason R., Camp, J. Gray

“…Organs are composed of diverse cell types that traverse transient states during organogenesis. To interrogate this diversity during human development, we…”
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Recent advances in the molecular prognostication of meningiomas by Wang, Elaina J, Haddad, Alexander F, Young, Jacob S, Morshed, Ramin A, Wu, Joshua P H, Salha, Diana M, Butowski, Nicholas, Aghi, Manish K

“…Meningiomas are the most common primary intracranial neoplasm. While traditionally viewed as benign, meningiomas are associated with significant patient…”
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Suspension culture promotes serosal mesothelial development in human intestinal organoids by Capeling, Meghan M., Huang, Sha, Childs, Charlie J., Wu, Joshua H., Tsai, Yu-Hwai, Wu, Angeline, Garg, Neil, Holloway, Emily M., Sundaram, Nambirajan, Bouffi, Carine, Helmrath, Michael, Spence, Jason R.

“…Pluripotent-stem-cell-derived human intestinal organoids (HIOs) model some aspects of intestinal development and disease, but current culture methods do not…”
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Mapping the adult human esophagus in vivo and in vitro by Ferrer-Torres, Daysha, Wu, Joshua H, Zhang, Charles J, Hammer, Max A, Dame, Michael K, Wu, Angeline, Holloway, Emily M, Karpoff, Kateryna, McCarthy, Caroline L, Bohm, Margaret S, Cuttitta, Ashley J, Tigani, Dominic J, Huang, Sha, Tsai, Yu-Hwai, Miller, Alyssa J, Walker, Taylor, Bayer, David E, Hogan, Simon P, Turgeon, Danielle Kim, Lin, Jules, Higgins, Peter D R, Sexton, Jonathan, Spence, Jason R

“…Many esophageal diseases can arise during development or throughout life. Therefore, well-characterized in vitro models and detailed methods are essential for…”
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Acquisition of NOTCH dependence is a hallmark of human intestinal stem cell maturation by Tsai, Yu-Hwai, Wu, Angeline, Wu, Joshua H., Capeling, Meghan M., Holloway, Emily M., Huang, Sha, Czerwinkski, Michael, Glass, Ian, Higgins, Peter D.R., Spence, Jason R.

“…NOTCH signaling is a key regulator involved in maintaining intestinal stem cell (ISC) homeostasis and for balancing differentiation. Using single-cell…”
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UBCH5 Family Members Differentially Impact Stabilization of Mutant p53 via RNF128 Iso1 During Barrett’s Progression to Esophageal Adenocarcinoma by Ray, Paramita, Nancarrow, Derek J., Ferrer-Torres, Daysha, Wang, Zhuwen, San Martinho, May, Hinton, Tonaye, Wu, Joshua H., Wu, Angeline, Turgeon, Danielle Kim, Hammer, Max A., Dame, Michael K., Lawrence, Theodore S., O’Brien, Patrick J., Spence, Jason R., Beer, David G., Ray, Dipankar

“…TP53 mutations underlie Barrett’s esophagus (BE) progression to dysplasia and cancer. During BE progression, the ubiquitin ligase (E3) RNF128/GRAIL switches…”
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S0832 Characterization of Intestinal Subepithelial PDGFRα(high), DLL1+, F3+ Cells in Ulcerative Colitis by Steiner, Calen A., Holloway, Emily, Childs, Charlie, Wu, Joshua H., Tsai, Yu-Hwai, Czerwinski, Mike, Sweet, Caden W., Taylor, Walker, Berinstein, Jeffrey A., Bearinger, Zack, Nusrat, Asma, Hou, Guoqing, Bishu, Shrinivas, Higgins, Peter D., Spence, Jason R.

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UBCH5 Family Members Differentially Impact Stabilization of Mutant p53 via RNF128 Iso1 During Barrett’s Progression to Esophageal AdenocarcinomaSummary by Paramita Ray, Derek J. Nancarrow, Daysha Ferrer-Torres, Zhuwen Wang, May San Martinho, Tonaye Hinton, Joshua H. Wu, Angeline Wu, Danielle Kim Turgeon, Max A. Hammer, Michael K. Dame, Theodore S. Lawrence, Patrick J. O’Brien, Jason R. Spence, David G. Beer, Dipankar Ray

“…Background & Aims: TP53 mutations underlie Barrett’s esophagus (BE) progression to dysplasia and cancer. During BE progression, the ubiquitin ligase (E3)…”
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Leaving Flatland: Advances in 3D behavioral measurement by Marshall, Jesse D, Li, Tianqing, Wu, Joshua H, Dunn, Timothy W

“…Animals move in three dimensions (3D). Thus, 3D measurement is necessary to report the true kinematics of animal movement. Existing 3D measurement techniques…”
Get full text