Vitreoretinal biomarkers of retinopathy of prematurity using handheld optical coherence tomography: a review

Retinopathy of prematurity (ROP) is caused by abnormal retinal vascularization in premature infants that has the potential for severe long-term vision impairment. Recent advancements in handheld optical coherence tomography (OCT) have enabled noninvasive, high-resolution, cross-sectional imaging of...

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Published in:Frontiers in pediatrics Vol. 11; p. 1191174
Main Authors: Kubsad, Deepika, Ohan, Masis A, Wu, Jolan G, Cabrera, Michelle T
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 31-05-2023
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Summary:Retinopathy of prematurity (ROP) is caused by abnormal retinal vascularization in premature infants that has the potential for severe long-term vision impairment. Recent advancements in handheld optical coherence tomography (OCT) have enabled noninvasive, high-resolution, cross-sectional imaging of the infant eye at the bedside. The use of handheld OCT devices in the diagnosis of ROP in premature infants has furthered our understanding of disease state and progression. This review discusses the known and novel biomarkers of ROP severity in premature infants identified through handheld OCT and potential for future directions.
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Reviewed by: Shwetha Mangalesh, Duke University, United States Sam Ebenezer Athikarisamy, University of Western Australia, Australia
Edited by: Mary Elizabeth Hartnett, University of Utah, United States
ISSN:2296-2360
2296-2360
DOI:10.3389/fped.2023.1191174