Search Results - "Wu, Jin’en"
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Argonaute proteins: Structural features, functions and emerging roles
Published in Journal of advanced research (01-07-2020)“…[Display omitted] Argonaute proteins are highly conserved in almost all organisms. They not only involve in the biogenesis of small regulatory RNAs, but also…”
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Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C
Published in mBio (26-10-2022)“…The maintenance of viral protein homeostasis depends on the machinery of the infected host cells, giving us an insight into the interplay between host and…”
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Identification of Different Extracellular Vesicles in the Hydatid Fluid of Echinococcus granulosus and Immunomodulatory Effects of 110 K EVs on Sheep PBMCs
Published in Frontiers in immunology (23-02-2021)“…Echinococcosis, mainly caused by , is one of the 17 neglected tropical diseases. Extracellular vesicles (EVs) play an essential role in the host-parasite…”
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Nuclear ribonucleoprotein RALY downregulates foot-and-mouth disease virus replication but antagonized by viral 3C protease
Published in Microbiology spectrum (05-03-2024)“…The internal ribosome entry site (IRES) element constitutes a cis-acting RNA regulatory sequence that recruits the ribosomal initiation complex in a…”
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Advances and Breakthroughs in IRES-Directed Translation and Replication of Picornaviruses
Published in mBio (25-04-2023)“…Viruses lack the properties to replicate independently due to the limited resources encoded in their genome; therefore, they hijack the host cell machinery to…”
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MicroRNA Roles in the Nuclear Factor Kappa B Signaling Pathway in Cancer
Published in Frontiers in immunology (19-03-2018)“…Nuclear factor kappa B (NF-κB) is a pluripotent and crucial dimer transcription factor that orchestrates various physiological and pathological processes,…”
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Ribosomal Protein L13 Participates in Innate Immune Response Induced by Foot-and-Mouth Disease Virus
Published in Frontiers in immunology (20-05-2021)“…In addition to ribosomal protein synthesis and protein translation, ribosomal proteins also participate in tumorigenesis and tumor progression, immune…”
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DDX21, a Host Restriction Factor of FMDV IRES-Dependent Translation and Replication
Published in Viruses (03-09-2021)“…In cells, the contributions of DEAD-box helicases (DDXs), without which cellular life is impossible, are of utmost importance. The extremely diverse roles of…”
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Sec62 Regulates Endoplasmic Reticulum Stress and Autophagy Balance to Affect Foot-and-Mouth Disease Virus Replication
Published in Frontiers in cellular and infection microbiology (31-08-2021)“…Endoplasmic reticulum (ER) stress-induced autophagy is closely associated with viral infection and propagation. However, the intrinsic link between ER stress,…”
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miRNA-seq of Echinococcus multilocularis Extracellular Vesicles and Immunomodulatory Effects of miR-4989
Published in Frontiers in microbiology (29-11-2019)“…Alveolar echinococcosis caused by is an important zoonotic disease. In the infected mice, emu-miR-4989-3p is present in sera, but its role remains unknown…”
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The DDX23 Negatively Regulates Translation and Replication of Foot-and-Mouth Disease Virus and Is Degraded by 3C Proteinase
Published in Viruses (25-11-2020)“…DEAD-box helicase 23 (DDX23) is a host nuclear helicase, which is a part of the spliceosomal complex and involved in pre-mRNA splicing. To investigate whether…”
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Comparative analysis of miRNAs in exosomes released by sheeppox virus-infected ovine testicular cells
Published in Comparative immunology, microbiology and infectious diseases (01-12-2019)“…•All three exosome samples were spherical, ranging from 39 nm to 127 nm in diameter.•A total of 34 known miRNAs were aberrantly expressed in the exosomes from…”
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Foot-and-mouth disease virus downregulates vacuolar protein sorting 28 to promote viral replication
Published in Journal of virology (31-08-2023)“…Vacuolar protein sorting 28 (Vps28), a component of the ESCRT-I (endosomal sorting complex required for transport I), plays an important role in the pathogen…”
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FGFR1-mediated enhancement of foot-and-mouth disease virus entry
Published in Veterinary microbiology (01-11-2024)“…Foot-and-mouth disease virus (FMDV), a member of picornavirus, can enter into host cell via macropinocytosis. Although it is known that receptor tyrosine…”
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Dendritic cell-based biomimetic nanoparticles for foot-and-mouth disease induce robust cellular immunity
Published in Antiviral research (01-11-2024)“…Foot-and-mouth disease (FMD) is a highly contagious and economically devastating viral disease of ruminants and swine, badly affecting the livestock industry…”
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Exosomes in virus-associated cancer
Published in Cancer letters (01-12-2018)“…Exosomes are phospholipid bilayer membrane-enclosed vesicles in a size from 30 to 150 nm, carrying a variety of active components, such as proteins, mRNA and…”
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Comparative analysis of different extracellular vesicles secreted by Echinococcus granulosus protoscoleces
Published in Acta tropica (01-01-2021)“…•3 different EVs secreted by Echinococcus granulosus protoscolex, and named as 2K EVs, 10K EVs and 110K EVs.•A total of 901 EV proteins were identified, 328 of…”
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Gut bacteria formation and influencing factors
Published in FEMS microbiology ecology (01-04-2021)“…ABSTRACT The gut microbiota plays an important role in human health. In modern life, with the improvement of living conditions, the intake of high-sugar and…”
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High-throughput identification of microRNAs in Taenia hydatigena, a cestode threatening livestock breeding industry
Published in Infection, genetics and evolution (01-11-2019)“…Infection of Cysticercus tenuicollis, the larval stage of Taenia hydatigena, is extensively found in sheep and pigs and jeopardizes the breeding and meat…”
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Nucleolin Promotes IRES-Driven Translation of Foot-and-Mouth Disease Virus by Supporting the Assembly of Translation Initiation Complexes
Published in Journal of virology (10-06-2021)“…Nucleolin (NCL), a stress-responsive RNA-binding protein, has been implicated in the translation of internal ribosome entry site (IRES)-containing mRNAs, which…”
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