Search Results - "Wu, Jichuan"
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Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation
Published in Nature nanotechnology (01-01-2022)“…This study shows that the supramolecular arrangement of proteins in nanoparticle structures predicts nanoparticle accumulation in neutrophils in acute lung…”
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HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction
Published in Science translational medicine (08-01-2020)“…Heart failure with preserved ejection fraction (HFpEF) is a major health problem without effective therapies. This study assessed the effects of histone…”
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Simulation study on the thermal effect of continuous laser heating quartz materials
Published in Frontiers in chemistry (23-07-2024)“…The continuous development and application of laser technology, and the increasing energy and power of laser output have promoted the development of various…”
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Nanoparticle-Induced Augmentation of Neutrophils' Phagocytosis of Bacteria
Published in Frontiers in pharmacology (04-07-2022)“…Despite the power of antibiotics, bacterial infections remain a major killer, due to antibiotic resistance and hosts with dysregulated immune systems. We and…”
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Mechanisms by Which Liposomes Improve Inhaled Drug Delivery for Alveolar Diseases
Published in Advanced NanoBiomed Research (Online) (01-03-2023)“…Diseases of the pulmonary alveolus, such as pulmonary fibrosis, are leading causes of morbidity and mortality, but exceedingly few drugs are developed for…”
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β-Defensins Coordinate In Vivo to Inhibit Bacterial Infections of the Trachea
Published in Vaccines (Basel) (28-08-2018)“…β-defensins are predicted to play an important role in innate immunity against bacterial infections in the airway. We previously observed that a type…”
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A Novel Approach for Ovine Primary Alveolar Epithelial Type II Cell Isolation and Culture from Fresh and Cryopreserved Tissue Obtained from Premature and Juvenile Animals
Published in PloS one (21-03-2016)“…The in vivo ovine model provides a clinically relevant platform to study cardiopulmonary mechanisms and treatments of disease; however, a robust ovine primary…”
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Effect of serum 25‐hydroxyvitamin D3 on insulin resistance and β‐cell function in newly diagnosed type 2 diabetes patients
Published in Journal of diabetes investigation (01-03-2016)“…Aims/Introduction To evaluate serum 25‐hydroxyvitamin D3 (25(OH)D3) in newly diagnosed type 2 diabetes patients and to explore the associations of 25(OH)D3…”
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Lucinactant attenuates pulmonary inflammatory response, preserves lung structure, and improves physiologic outcomes in a preterm lamb model of RDS
Published in Pediatric research (01-10-2012)“…Background: Acute inflammatory responses to supplemental oxygen and mechanical ventilation have been implicated in the pathophysiological sequelae of…”
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Association study of genetic variants in eight genes/loci with type 2 diabetes in a Han Chinese population
Published in BMC medical genetics (15-06-2010)“…At least twenty genes/loci were shown to be associated with type 2diabetes in European original populations. Five of these genes were shown to be associated…”
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A Software Component Approach for GPU Accelerated Physics-Based Blood Flow Simulation
Published in 2015 IEEE International Conference on Systems, Man, and Cybernetics (01-10-2015)“…High-fidelity patient specific model for blood flow simulation is important in medical applications. In this paper, a software component approach is proposed…”
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Conference Proceeding -
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Perfluorochemical Liquid-Adenovirus Suspensions Enhance Gene Delivery to the Distal Lung
Published in Pulmonary Medicine (01-01-2011)“…We compared lung delivery methods of recombinant adenovirus (rAd): (1) rAd suspended in saline, (2) rAd suspended in saline followed by a pulse-chase of a…”
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13
Intranasal Perfluorochemical Spray for Preferential Brain Cooling in Sheep
Published in Neurocritical care (01-06-2008)Get full text
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14
Experimental investigation for pulsed laser nitriding of metals
Published in Optics and laser technology (01-01-2023)“…Under the pulsed laser illumination, the metal surface could melt and the laser-supported-detonation (LSD) could be created in the plasma. The LSD may enable…”
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Formation of flower-like Cu2O thin films induced by nitrate through electro-deposition for PEC water reduction
Published in Ionics (06-09-2024)Get full text
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Inhibitor of DNA Binding 3 Is a Potential Prognostic Biomarker in Non-GCB Diffuse Large B-Cell Lymphoma
Published in Blood (05-11-2020)“…Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma. The majority of patients can be cured under the treatment…”
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Combination of Physicochemical Tropism and Affinity Moiety Targeting of Lipid Nanoparticles Enhances Organ Targeting
Published in Nano letters (10-04-2024)“…Two camps have emerged for targeting nanoparticles to specific organs and cell types: affinity moiety targeting and physicochemical tropism. Here we directly…”
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The mechanism of loss in the impedance spectrum of longitudinal piezoelectric oscillator
Published in Journal of materials science. Materials in electronics (01-03-2024)“…Loss is a critical performance metric in piezoelectric devices, directly impacting energy conversion efficiency and the overall stability of device operation…”
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Physicochemical Targeting of Lipid Nanoparticles to the Lungs Induces Clotting: Mechanisms and Solutions
Published in Advanced materials (Weinheim) (01-06-2024)“…Lipid nanoparticles (LNPs) have become the dominant drug delivery technology in industry, holding the promise to deliver RNA to up or down‐regulate any protein…”
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Dual Affinity to RBCs and Target Cells (DART) Enhances Both Organ- and Cell Type-Targeting of Intravascular Nanocarriers
Published in ACS nano (22-03-2022)“…A long-standing goal of nanomedicine is to improve a drug’s benefit by loading it into a nanocarrier that homes solely to a specific target cell and organ…”
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