Search Results - "Wu, Jianye"
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Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma
Published in Journal of experimental & clinical cancer research (06-07-2020)“…Liver cancer has become the sixth most diagnosed cancer and the fourth leading cause of cancer death worldwide. Hepatocellular carcinoma (HCC) is responsible…”
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Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis
Published in Journal of experimental & clinical cancer research (30-01-2020)“…Hepatocellular carcinoma (HCC) is a common primary malignant tumor which usually progresses to an advanced stage because of late diagnosis. Sorafenib (Sora) is…”
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3
The gut microbiome-bile acid axis in hepatocarcinogenesis
Published in Biomedicine & pharmacotherapy (01-01-2021)“…[Display omitted] •Altered BA levels may promote tumorgenesis.•Gut microbiome is correlate with and mediate the onset of HCC.•BAs metabolism is greatly…”
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Astaxanthin in Liver Health and Disease: A Potential Therapeutic Agent
Published in Drug design, development and therapy (01-01-2020)“…Astaxanthin is a carotenoid derived from oxygen-containing non-vitamin A sources and is mainly obtained from marine organisms. Studies have demonstrated that…”
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Targeting fatty acid synthase modulates sensitivity of hepatocellular carcinoma to sorafenib via ferroptosis
Published in Journal of experimental & clinical cancer research (06-01-2023)“…Sorafenib resistance is a key impediment to successful treatment of patients with advanced hepatocellular carcinoma (HCC) and recent studies have reported…”
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Crosstalk between PPARs and gut microbiota in NAFLD
Published in Biomedicine & pharmacotherapy (01-04-2021)“…[Display omitted] •Gut microbiome is correlate with NAFLD.•The role of PPARs in NAFLD pathogenesis.•The possible link between PPARs and gut microbiota in…”
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Deciphering roles of TRIMs as promising targets in hepatocellular carcinoma: current advances and future directions
Published in Biomedicine & pharmacotherapy (01-11-2023)“…Tripartite motif (TRIM) family is assigned to RING-finger-containing ligases harboring the largest number of proteins in E3 ubiquitin ligating enzymes. E3…”
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PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma
Published in Journal of experimental & clinical cancer research (17-05-2019)“…The treatment for advanced primary hepatocellular carcinoma (HCC) is sorafenib (SORA), while HCC has become increasingly drug resistant with enhanced aerobic…”
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Quercetin shows anti‐tumor effect in hepatocellular carcinoma LM3 cells by abrogating JAK2/STAT3 signaling pathway
Published in Cancer medicine (Malden, MA) (01-08-2019)“…Objective Hepatocellular carcinima is one of the most common tumors in clinic and also one of the leading causes of death from cancer worldwide. Quercetin…”
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Current status of ctDNA in precision oncology for hepatocellular carcinoma
Published in Journal of experimental & clinical cancer research (26-04-2021)“…The conventional method used to obtain a tumor biopsy for hepatocellular carcinoma (HCC) is invasive and does not evaluate dynamic cancer progression or assess…”
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11
Cellular based immunotherapy for primary liver cancer
Published in Journal of experimental & clinical cancer research (09-08-2021)“…Primary liver cancer (PLC) is a common malignancy with high morbidity and mortality. Poor prognosis and easy recurrence on PLC patients calls for optimizations…”
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12
Cordycepin Protects against Hepatic Ischemia/Reperfusion Injury via Inhibiting MAPK/NF-κB Pathway
Published in Mediators of inflammation (22-07-2022)“…Hepatic ischemia/reperfusion injury (HIRI) is a common complication of liver surgery requiring hepatic disconnection, such as hepatectomy and liver…”
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Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy
Published in Mediators of inflammation (01-01-2019)“…Hepatic ischemia reperfusion (IR) injury (IRI) occurs during liver transplantation, hepatectomy, and hemorrhagic shock. Oleanolic acid (OA) is a natural…”
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14
Promotion of colorectal cancer cell death by ezetimibe via mTOR signaling-dependent mitochondrial dysfunction
Published in Frontiers in pharmacology (07-02-2023)“…Colorectal cancer (CRC) is the fourth most common cancer worldwide, with high morbidity and mortality rates. In recent years, high-fat diet has been shown to…”
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Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation
Published in PPAR research (2021)“…Hepatic ischemia and reperfusion injury is characterized by hepatocyte apoptosis, impaired autophagy, and oxidative stress. Fenofibrate, a commonly used…”
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Luteolin Pretreatment Attenuates Hepatic Ischemia-Reperfusion Injury in Mice by Inhibiting Inflammation, Autophagy, and Apoptosis via the ERK/PPARα Pathway
Published in PPAR research (03-08-2022)“…Hepatic ischemia-reperfusion (IR) injury is a clinically significant process that frequently occurs in liver transplantation, partial hepatectomy, and…”
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Correction to: Current status of ctDNA in precision oncology for hepatocellular carcinoma
Published in Journal of experimental & clinical cancer research (13-07-2021)Get full text
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18
Effect of a Modified Atmosphere on Drying and Quality Characteristics of Carrots
Published in Food and bioprocess technology (01-09-2014)“…Many quality degradation problems are related to the high O₂ content of normal air atmosphere during drying. To reduce O₂ content in drying atmosphere and…”
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15-Deoxy-∆-12,14-Prostaglandin J2 (15d-PGJ2), an Endogenous Ligand of PPAR-γ: Function and Mechanism
Published in PPAR research (2019)“…15-Deoxy-∆-12,14-prostaglandin J2 (15d-PGJ2), a natural peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist, has been explored in some detail over…”
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Therapeutic potential of PPARγ natural agonists in liver diseases
Published in Journal of cellular and molecular medicine (01-03-2020)“…Peroxisome proliferator‐activated receptor gamma (PPARγ) is a vital subtype of the PPAR family. The biological functions are complex and diverse. PPARγ plays a…”
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