Search Results - "Wu, Jianye"

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  1. 1

    Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma by Feng, Jiao, Li, Jingjing, Wu, Liwei, Yu, Qiang, Ji, Jie, Wu, Jianye, Dai, Weiqi, Guo, Chuanyong

    “…Liver cancer has become the sixth most diagnosed cancer and the fourth leading cause of cancer death worldwide. Hepatocellular carcinoma (HCC) is responsible…”
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  2. 2

    Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis by Feng, Jiao, Dai, Weiqi, Mao, Yuqing, Wu, Liwei, Li, Jingjing, Chen, Kan, Yu, Qiang, Kong, Rui, Li, Sainan, Zhang, Jie, Ji, Jie, Wu, Jianye, Mo, Wenhui, Xu, Xuanfu, Guo, Chuanyong

    “…Hepatocellular carcinoma (HCC) is a common primary malignant tumor which usually progresses to an advanced stage because of late diagnosis. Sorafenib (Sora) is…”
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  3. 3

    The gut microbiome-bile acid axis in hepatocarcinogenesis by Wu, Liwei, Feng, Jiao, Li, Jingjing, Yu, Qiang, Ji, Jie, Wu, Jianye, Dai, Weiqi, Guo, Chuanyong

    Published in Biomedicine & pharmacotherapy (01-01-2021)
    “…[Display omitted] •Altered BA levels may promote tumorgenesis.•Gut microbiome is correlate with and mediate the onset of HCC.•BAs metabolism is greatly…”
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  4. 4

    Astaxanthin in Liver Health and Disease: A Potential Therapeutic Agent by Li, Jingjing, Guo, Chuanyong, Wu, Jianye

    Published in Drug design, development and therapy (01-01-2020)
    “…Astaxanthin is a carotenoid derived from oxygen-containing non-vitamin A sources and is mainly obtained from marine organisms. Studies have demonstrated that…”
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  5. 5

    Targeting fatty acid synthase modulates sensitivity of hepatocellular carcinoma to sorafenib via ferroptosis by Li, Yan, Yang, Wenjuan, Zheng, Yuanyuan, Dai, Weiqi, Ji, Jie, Wu, Liwei, Cheng, Ziqi, Zhang, Jie, Li, Jingjing, Xu, Xuanfu, Wu, Jianye, Yang, Mingwei, Feng, Jiao, Guo, Chuanyong

    “…Sorafenib resistance is a key impediment to successful treatment of patients with advanced hepatocellular carcinoma (HCC) and recent studies have reported…”
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  6. 6

    Crosstalk between PPARs and gut microbiota in NAFLD by Wu, Liwei, Li, Jingjing, Feng, Jiao, Ji, Jie, Yu, Qiang, Li, Yan, Zheng, Yuanyuan, Dai, Weiqi, Wu, Jianye, Guo, Chuanyong

    Published in Biomedicine & pharmacotherapy (01-04-2021)
    “…[Display omitted] •Gut microbiome is correlate with NAFLD.•The role of PPARs in NAFLD pathogenesis.•The possible link between PPARs and gut microbiota in…”
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  7. 7

    Deciphering roles of TRIMs as promising targets in hepatocellular carcinoma: current advances and future directions by Zhang, Jie, Zhou, Yuting, Feng, Jiao, Xu, Xuanfu, Wu, Jianye, Guo, Chuanyong

    Published in Biomedicine & pharmacotherapy (01-11-2023)
    “…Tripartite motif (TRIM) family is assigned to RING-finger-containing ligases harboring the largest number of proteins in E3 ubiquitin ligating enzymes. E3…”
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  8. 8

    PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma by Feng, Jiao, Wu, Liwei, Ji, Jie, Chen, Kan, Yu, Qiang, Zhang, Jie, Chen, Jiaojiao, Mao, Yuqing, Wang, Fan, Dai, Weiqi, Xu, Ling, Wu, Jianye, Guo, Chuanyong

    “…The treatment for advanced primary hepatocellular carcinoma (HCC) is sorafenib (SORA), while HCC has become increasingly drug resistant with enhanced aerobic…”
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  9. 9

    Quercetin shows anti‐tumor effect in hepatocellular carcinoma LM3 cells by abrogating JAK2/STAT3 signaling pathway by Wu, Liwei, Li, Jingjing, Liu, Tong, Li, Sainan, Feng, Jiao, Yu, Qiang, Zhang, Jie, Chen, Jiaojiao, Zhou, Yuting, Ji, Jie, Chen, Kan, Mao, Yuqing, Wang, Fan, Dai, Weiqi, Fan, Xiaoming, Wu, Jianye, Guo, Chuanyong

    Published in Cancer medicine (Malden, MA) (01-08-2019)
    “…Objective Hepatocellular carcinima is one of the most common tumors in clinic and also one of the leading causes of death from cancer worldwide. Quercetin…”
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  10. 10

    Current status of ctDNA in precision oncology for hepatocellular carcinoma by Li, Yan, Zheng, Yuanyuan, Wu, Liwei, Li, Jingjing, Ji, Jie, Yu, Qiang, Dai, Weiqi, Feng, Jiao, Wu, Jianye, Guo, Chuanyong

    “…The conventional method used to obtain a tumor biopsy for hepatocellular carcinoma (HCC) is invasive and does not evaluate dynamic cancer progression or assess…”
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  11. 11

    Cellular based immunotherapy for primary liver cancer by Zheng, Yuanyuan, Li, Yan, Feng, Jiao, Li, Jingjing, Ji, Jie, Wu, Liwei, Yu, Qiang, Dai, Weiqi, Wu, Jianye, Zhou, Yingqun, Guo, Chuanyong

    “…Primary liver cancer (PLC) is a common malignancy with high morbidity and mortality. Poor prognosis and easy recurrence on PLC patients calls for optimizations…”
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  12. 12

    Cordycepin Protects against Hepatic Ischemia/Reperfusion Injury via Inhibiting MAPK/NF-κB Pathway by Ding, Jiameng, WenjuanYang, Jiang, Yuhui, Ji, Jie, Zhang, Jie, Wu, Liwei, Feng, Jiao, Zheng, Yuanyuan, Li, Yan, Cheng, Ziqi, Yu, Qiang, Wu, Jianye, Li, Jingjing, Chen, Kan, Guo, Chuanyong

    Published in Mediators of inflammation (22-07-2022)
    “…Hepatic ischemia/reperfusion injury (HIRI) is a common complication of liver surgery requiring hepatic disconnection, such as hepatectomy and liver…”
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  13. 13
  14. 14

    Promotion of colorectal cancer cell death by ezetimibe via mTOR signaling-dependent mitochondrial dysfunction by Zheng, Yuanyuan, Yang, Wenjuan, Jia, Yewei, Ji, Jie, Wu, Liwei, Feng, Jiao, Li, Yan, Cheng, Ziqi, Zhang, Jie, Li, Jingjing, Dai, Weiqi, Xu, Xuanfu, Wu, Jianye, Zhou, Yingqun, Guo, Chuanyong

    Published in Frontiers in pharmacology (07-02-2023)
    “…Colorectal cancer (CRC) is the fourth most common cancer worldwide, with high morbidity and mortality rates. In recent years, high-fat diet has been shown to…”
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  15. 15

    Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation by Zhang, Jie, Cheng, Ping, Dai, Weiqi, Ji, Jie, Wu, Liwei, Feng, Jiao, Wu, Jianye, Yu, Qiang, Li, Jingjing, Guo, Chuanyong

    Published in PPAR research (2021)
    “…Hepatic ischemia and reperfusion injury is characterized by hepatocyte apoptosis, impaired autophagy, and oxidative stress. Fenofibrate, a commonly used…”
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  16. 16

    Luteolin Pretreatment Attenuates Hepatic Ischemia-Reperfusion Injury in Mice by Inhibiting Inflammation, Autophagy, and Apoptosis via the ERK/PPARα Pathway by Jiang, Yuhui, Yang, Wenjuan, Ding, Jiameng, Ji, Jie, Wu, Liwei, Zheng, Yuanyuan, Li, Yan, Cheng, Ziqi, Zhang, Jie, Yu, Qiang, Feng, Jiao, Li, Jingjing, Wu, Jianye, Zhou, Yingqun, Guo, Chuanyong

    Published in PPAR research (03-08-2022)
    “…Hepatic ischemia-reperfusion (IR) injury is a clinically significant process that frequently occurs in liver transplantation, partial hepatectomy, and…”
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  17. 17
  18. 18

    Effect of a Modified Atmosphere on Drying and Quality Characteristics of Carrots by Liu, Yunhong, Wu, Jianye, Miao, Shuai, Chong, Cuijuan, Sun, Yue

    Published in Food and bioprocess technology (01-09-2014)
    “…Many quality degradation problems are related to the high O₂ content of normal air atmosphere during drying. To reduce O₂ content in drying atmosphere and…”
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  19. 19

    15-Deoxy-∆-12,14-Prostaglandin J2 (15d-PGJ2), an Endogenous Ligand of PPAR-γ: Function and Mechanism by Li, Jingjing, Wu, Jian-Ye, Guo, Chuan-Yong

    Published in PPAR research (2019)
    “…15-Deoxy-∆-12,14-prostaglandin J2 (15d-PGJ2), a natural peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist, has been explored in some detail over…”
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  20. 20

    Therapeutic potential of PPARγ natural agonists in liver diseases by Wu, Liwei, Guo, Chuanyong, Wu, Jianye

    Published in Journal of cellular and molecular medicine (01-03-2020)
    “…Peroxisome proliferator‐activated receptor gamma (PPARγ) is a vital subtype of the PPAR family. The biological functions are complex and diverse. PPARγ plays a…”
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