Search Results - "Wu, JT"

A novel liquid chromatography/tandem mass spectrometry based depletion method for measuring red blood cell partitioning of pharmaceutical compounds in drug discovery by Yu, Shaoxia, Li, Shelly, Yang, Hua, Lee, Frank, Wu, Jing-Tao, Qian, Mark G.

“…A novel liquid chromatography/tandem mass spectrometry (LC/MS/MS)‐based depletion method for measuring compound partitioning between human plasma and red blood…”
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Clinical assessment of COVID-19 outbreak among migrant workers residing in a large dormitory in Singapore by Chew, MH, Koh, F.H., Wu, JT, Ngaserin, S., Ng, A., Ong, BC, Lee, V.J.

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HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor by Kovacs, Jeffrey J., Murphy, Patrick J.M., Gaillard, Stéphanie, Zhao, Xuan, Wu, June-Tai, Nicchitta, Christopher V., Yoshida, Minoru, Toft, David O., Pratt, William B., Yao, Tso-Pang

“…The molecular chaperone heat shock protein 90 (Hsp90) and its accessory cochaperones function by facilitating the structural maturation and complex assembly of…”
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Immediate extubation after heart transplantation in a child by remifentanil-based ultra-fast anesthesia: A case report by Yao, Yong-Xing, Wu, Jia-Teng, Zhu, Wei-Liu, Zhu, Sheng-Mei

“…Ventilator-associated complications comprise important fatal aetiologies during heart transplantation. Ultra-fast anesthesia might provide the most effective…”
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Urinary 8-OHdG: a marker of oxidative stress to DNA and a risk factor for cancer, atherosclerosis and diabetics by Wu, Lily L., Chiou, Chiuan-Chian, Chang, Pi-Yueh, Wu, James T.

“…Reactive oxygen species (ROS) produced either endogenously or exogenously can attack lipid, protein and nucleic acid simultaneously in the living cells. In…”
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Effects of initial microstructures on the microstructural evolution and corresponding mechanical property of K424 superalloy after overheating exposure by Yuan, X.F., Wu, J.T., Li, J.T., Li, W., Zhao, J.C., Yan, P.

“…Service safety and maintenance costs of turbine components after overheating exposure are closely related to the initial microstructures and subsequent…”
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A human [11C]T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor by Takano, Akihiro, Stenkrona, Per, Stepanov, Vladimir, Amini, Nahid, Martinsson, Stefan, Tsai, Max, Goldsmith, Paul, Xie, Jinhui, Wu, Jingtao, Uz, Tolga, Halldin, Christer, Macek, Thomas A.

“…Phosphodiesterase 10A (PDE10A) is selectively expressed in the striatal regions in the brain and may play a role in modulating dopaminergic and glutamatergic…”
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Role of capsaicin- and heat-sensitive afferents in stimulation of acupoint-induced pain and analgesia in humans by Lei, Jing, Ye, Gang, Wu, Jiang-Tao, Pertovaara, Antti, You, Hao-Jun

“…•Pain elicited from the stimulation of acupoint and non-acupoint area differs significantly.•Differences exist between treatments of different acupoints in the…”
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Analysis of heterogeneous dengue transmission in Guangdong in 2014 with multivariate time series model by Cheng, Qing, Lu, Xin, Wu, Joseph T., Liu, Zhong, Huang, Jincai

“…Guangdong experienced the largest dengue epidemic in recent history. In 2014, the number of dengue cases was the highest in the previous 10 years and comprised…”
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The NF-κB/IκB signaling system: A molecular target in breast cancer therapy by Wu, James T., Kral, John G.

“…The nuclear factor κB (NFκB) superfamily of eukaryotic transcription factors plays an important role in carcinogenesis. NF-κB and its regulators are linked to…”
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The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation by Hinnebusch, Brian F, Meng, Shufen, Wu, James T, Archer, Sonia Y, Hodin, Richard A

“…The short-chain fatty acid (SCFA) butyrate is produced via anaerobic bacterial fermentation within the colon and is thought to be protective in regard to colon…”
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Hyperhomocysteinemia is a risk factor for cancer and a new potential tumor marker by Wu, Lily L, Wu, James T

“…Plasma homocysteine (Hcy), a well-known independent risk factor for coronary heart disease, is also a risk factor for cancer. Results from our studies indicate…”
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Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation by Chien, Cheng-Ting, Wu, June-Tai, Lin, Hsiu-Chen, Hu, Yen-Chen

“…Cullin family proteins organize ubiquitin ligase (E3) complexes to target numerous cellular proteins for proteasomal degradation. Neddylation, the process that…”
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Reduction of PAH and soot in premixed ethylene–air flames by addition of ethanol by Wu, Juntao, Song, Ki Hoon, Litzinger, Thomas, Lee, Seong-Young, Santoro, Robert, Linevsky, Milton, Colket, Meredith, Liscinsky, David

“…Results are presented from a combined experimental and modeling study undertaken to understand the pathways by which the addition of ethanol to fuel-rich…”
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Ghrelin: Integrative neuroendocrine peptide in health and disease by WU, James T, KRAL, John G

“…Ghrelin is a novel gastric hormone recognized in 1999 as a mediator of growth hormone release. Since growth hormone is anabolic, an important function of…”
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Validation and analysis of a mathematical model of a replication-competent oncolytic virus for cancer treatment: Implications for virus design and delivery by WEIN, Lawrence M, WU, Joseph T, KIRN, David H

“…Motivated by the rapid expansion in the development of replication-competent viral agents for the treatment of solid tumors, we formulated and analyzed a…”
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Preliminary inferences on the age-specific seriousness of human disease caused by avian influenza A(H7N9) infections in China, March to April 2013 by Cowling, B J, Freeman, G, Wong, J Y, Wu, P, Liao, Q, Lau, E H, Wu, J T, Fielding, R, Leung, G M

“…Between 31 March and 21 April 2013, 102 laboratory-confirmed influenza A(H7N9) infections have been reported in six provinces of China. Using survey data on…”
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A highly linear 125-MHz CMOS switched-resistor programmable-gain amplifier by Hsu, Cheng-Chung, Wu, Jieh-Tsorng

“…A highly linear programmable-gain amplifier (PGA) is fabricated using a 0.35-/spl mu/m CMOS technology. High linearity and constant wide bandwidth are achieved…”
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MOS charge pumps for low-voltage operation by Wu, Jieh-Tsorng, Chang, Kuen-Long

“…New MOS charge pumps utilizing the charge transfer switches (CTSs) to direct charge flow and generate boosted output voltage are described. Using the internal…”
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Strategy of utilizing in vitro and in vivo ADME tools for lead optimization and drug candidate selection by Balani, Suresh K, Miwa, Gerald T, Gan, Liang-Shang, Wu, Jing-Tao, Lee, Frank W

“…The high-throughput screening in drug discovery for absorption, distribution, metabolism and excretion (ADME) properties has become the norm in the industry…”
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