Search Results - "Wu, Hung‐Tsung"
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1
Insulin-Directed Synthesis of Fluorescent Gold Nanoclusters: Preservation of Insulin Bioactivity and Versatility in Cell Imaging
Published in Angewandte Chemie International Edition (25-07-2011)“…Go for gold: As‐prepared insulin–Au nanoclusters (NCs) show intense red fluorescence, excellent biocompatibility, and preservation of natural insulin…”
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2
Aspartame Intake Delayed Puberty Onset in Female Offspring Rats and Girls
Published in Molecular nutrition & food research (01-03-2024)“…Scope The disturbance of the hypothalamic–pituitary‐gonadal (HPG) axis, gut microbiota (GM) community, and short‐chain fatty acids (SCFAs) is a triggering…”
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3
Evodiamine Exhibits Anti-Bladder Cancer Activity by Suppression of Glutathione Peroxidase 4 and Induction of Ferroptosis
Published in International journal of molecular sciences (23-03-2023)“…Evodiamine (EVO) exhibits anti-cancer activity through the inhibition of cell proliferation; however, little is known about its underlying mechanism. To…”
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4
Elovl6 is a negative clinical predictor for liver cancer and knockdown of Elovl6 reduces murine liver cancer progression
Published in Scientific reports (26-04-2018)“…The elongation of long-chain fatty acids family member 6 (Elovl6) is a key enzyme in lipogenesis that catalyzes the elongation of saturated and monounsaturated…”
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5
Targeting fibrinogen‐like protein 1 is a novel therapeutic strategy to combat obesity
Published in The FASEB journal (01-02-2020)“…Fibrinogen‐like‐protein 1 (FGL1) is a novel hepatokine that plays an important role in hepatic steatosis and insulin resistance. Although FGL1 expression can…”
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6
Life course body mass index through childhood and young adulthood and risks of asthma and pulmonary function impairment
Published in Pediatric pulmonology (01-05-2021)“…Background Adiposity is a key risk factor for asthma and impaired pulmonary function. Objectives We aimed to identify the critical period of life course…”
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High-fat diet suppresses the astrocytic process arborization and downregulates the glial glutamate transporters in the hippocampus of mice
Published in Brain research (01-12-2018)“…•HFD induces astrocyte activation in the hippocampus.•HFD represses the process arborization of the hippocampal astrocytes.•HFD downregulates the hippocampal…”
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A novel hepatokine, HFREP1, plays a crucial role in the development of insulin resistance and type 2 diabetes
Published in Diabetologia (01-08-2016)“…Aims/hypothesis Type 2 diabetes is highly correlated with nonalcoholic fatty liver disease (NAFLD). Hepatocyte-derived fibrinogen-related protein 1 (HFREP1) is…”
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9
Consumption of Non-Nutritive Sweetener, Acesulfame Potassium Exacerbates Atherosclerosis through Dysregulation of Lipid Metabolism in ApoE−/− Mice
Published in Nutrients (09-11-2021)“…Obesity is associated with the risk of cardiovascular disease, and non-nutritive sweetener, such as acesulfame potassium (AceK) has been used to combat…”
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10
Evodiamine Exerts an Anti-Hepatocellular Carcinoma Activity through a WWOX-Dependent Pathway
Published in Molecules (Basel, Switzerland) (14-07-2017)“…Evodiamine is one of the main components isolated from , and it has been reported to exert inhibitory effects on cancers by anti-proliferative and…”
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11
Chronic exposure to high fat diet triggers myelin disruption and interleukin-33 upregulation in hypothalamus
Published in BMC neuroscience (10-07-2019)“…Hypothalamic inflammation including astrogliosis and microglia activation occurs after intake of high fat diet (HFD) in rodent models or in obese individuals…”
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Effects of Nonnutritive Sweeteners on Body Composition Changes during Pubertal Growth
Published in Nutrients (15-05-2023)“…The effects of consuming specific types of nonnutritive sweeteners (NNSs) on adiposity changes in children have remained inconsistent. In this study, we aimed…”
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Long-Term Consumption of Sucralose Induces Hepatic Insulin Resistance through an Extracellular Signal-Regulated Kinase 1/2-Dependent Pathway
Published in Nutrients (01-06-2023)“…Sugar substitutes have been recommended to be used for weight and glycemic control. However, numerous studies indicate that consumption of artificial…”
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Simple and Cost-effective Enzymatic Detection of Cholesterol Using Flow Injection Analysis
Published in Analytical Sciences (10-09-2020)“…A flow-injection analytical (FIA) system was developed for the determination of cholesterol concentrations based on enzymatic reactions that occurred in a…”
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Endoplasmic Reticulum Stress Induces the Expression of Fetuin-A to Develop Insulin Resistance
Published in Endocrinology (Philadelphia) (01-07-2012)“…Fetuin-A is a biomarker reported to be important in many metabolic disorders, including obesity, diabetes, and hepatic steatosis. Although it is well known…”
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Maternal Plasma Lipids During Pregnancy, Insulin-like Growth Factor-1, and Excess Fetal Growth
Published in The journal of clinical endocrinology and metabolism (01-09-2021)“…Abstract Context Maternal lipids during pregnancy and placental growth factors are associated with excess fetal growth. However, how these factors interact to…”
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Serum Angiopoietin-like Protein 6, Risk of Type 2 Diabetes, and Response to Hyperglycemia: A Prospective Cohort Study
Published in The journal of clinical endocrinology and metabolism (01-05-2020)“…Abstract Context Angiopoietin-like protein 6 (ANGPTL6) is a hepatokine that improves insulin sensitivity in animals. However, serum ANGPTL6 concentration was…”
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Growth differentiation factor‐15 is independently associated with metabolic syndrome and hyperglycemia in non‐elderly subjects
Published in BioFactors (Oxford) (01-01-2023)“…Metabolic syndrome (MetS) is a major health issue worldwide accompanied by cardiovascular comorbidities. Growth differentiation factor‐15 (GDF‐15) is a…”
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The Hepatic Protection Effects of Hepassocin in Hyperglycemic Crisis
Published in The journal of clinical endocrinology and metabolism (01-07-2017)“…Abstract Context: High glucose generates reactive oxygen species (ROS) and contributes to glucotoxicity in hepatocytes, and hyperglycemia causes structural and…”
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Coral Hydrate, a Novel Antioxidant, Improves Alcohol Intoxication in Mice
Published in Antioxidants (29-06-2022)“…Alcohol-drinking culture may cause individuals to periodically experience unpleasant hangovers. In addition, ethanol catabolism stimulates the production of…”
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