Search Results - "Wu, Guanzhao"

Butyrate mitigates metabolic dysfunctions via the ERα-AMPK pathway in muscle in OVX mice with diet-induced obesity by Fu, Qingsong, Li, Tiantian, Zhang, Chen, Ma, Xiaotian, Meng, Liying, Liu, Limin, Shao, Kai, Wu, Guanzhao, Zhu, Xing, Zhao, Xiaoyun

“…The higher prevalence of metabolic syndrome (MetS) in women after menopause is associated with a decrease in circulating 17β-oestradiol. To explore novel…”
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Design, Synthesis, and In Vitro/In Vivo Anti-Cancer Activities of Novel (20 S )-10,11-Methylenedioxy-Camptothecin Heterocyclic Derivatives by Dai, Xiufen, Wu, Guanzhao, Zhang, Yixuan, Zhang, Xiaomin, Yin, Ruijuan, Qi, Xin, Li, Jing, Jiang, Tao

“…A novel camptothecin analogue, (20S)-10,11-methylenedioxy-camptothecin (FL118), has been proven to show significant antitumor efficacy for a wide variety of…”
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Multilayer 3D Chirality and Its Synthetic Assembly by Wu, Guanzhao, Liu, Yangxue, Yang, Zhen, Katakam, Nandakumar, Rouh, Hossein, Ahmed, Sultan, Unruh, Daniel, Surowiec, Kazimierz, Li, Guigen

“…chirality of sandwich type of organic molecules has been discovered. The key element of this chirality is characterized by three layers of structures that are…”
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Triple-Columned and Multiple-Layered 3D Polymers: Design, Synthesis, Aggregation-Induced Emission (AIE), and Computational Study by Wu, Guanzhao, Liu, Yangxue, Yang, Zhen, Ma, Liulei, Tang, Yao, Zhao, Xianliang, Rouh, Hossein, Zheng, Qixuan, Zhou, Peng, Wang, Jia-Yin, Siddique, Farhan, Zhang, Sai, Jin, Shengzhou, Unruh, Daniel, Aquino, Adelia J A, Lischka, Hans, Hutchins, Kristin M, Li, Guigen

“…Conjugated polymers and oligomers have great potentials in various fields, especially in materials and biological sciences because of their intriguing…”
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Recent advances in fluorescent probes for ATP imaging by Zhang, Chen, Wu, Guanzhao

“…Adenosine-5′-triphosphate (ATP) is a critical biological molecule that functions as the primary energy currency within cells. ATP synthesis occurs in the…”
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Recent advances in small molecules for improving mitochondrial disorders by Meng, Liying, Wu, Guanzhao

“…Mitochondrial disorders are observed in various human diseases, including rare genetic disorders and complex acquired pathologies. Recent advances in molecular…”
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Recent progress toward developing axial chirality bioactive compounds by Wang, Zheyi, Meng, Liying, Liu, Xinxin, Zhang, Lingzi, Yu, Zongjiang, Wu, Guanzhao

“…Atropisomers are stereoisomers with axial chirality arising from restricted rotation around a single bond. Lots of representatives of this class of axially…”
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Design, synthesis, and biological evaluation of novel 7-substituted 10,11-methylenedioxy-camptothecin derivatives against drug-resistant small-cell lung cancer in vitro and in vivo by Zhang, Guorui, Yin, Ruijuan, Dai, Xiufei, Wu, Guanzhao, Qi, Xin, Yu, Rilei, Li, Jing, Jiang, Tao

“…A series of novel 7-substituted 10,11-methylenedioxy-camptothecin (FL118) derivatives were designed, synthesized, and biologically evaluated. All the FL118…”
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Differentiation of the Agonists and Antagonists of the α7 Nicotinic Acetylcholine Receptor by Wu, Guanzhao, Xu, Qingliang, Bao, Yilei, Liu, Yuwei, Li, Qian, Fang, Zhengyu, Fu, Jingyi, Ding, Yuhang, Liang, Zhiqing, Jiang, Tao, Yu, Rilei

“…The α7 nicotinic acetylcholine receptors (nAChRs) are widely expressed in the central and peripheral nervous systems and are important drug targets for the…”
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Discovery of novel SS-31 (d-Arg-dimethylTyr-Lys-Phe-NH 2 ) derivatives as potent agents to ameliorate inflammation and increase mitochondrial ATP synthesis by Li, Mei, Kong, Deyuan, Meng, Liying, Wang, Zheyi, Bai, Zetai, Wu, Guanzhao

“…Neuroinflammation and mitochondrial function are crucial for neuronal function and survival. SS-31 is a novel mitochondria-targeted peptide antioxidant that…”
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Synthesis of curcumin derivatives targeting androgen receptor for castration‐resistant prostate cancer therapy by Liu, Jiangfei, Ni, Yaohui, Zhou, Keyun, Wu, Guanzhao, Hu, Liangyong, Zhu, Tianyu, Xu, Defeng, Hu, Hang

“…In this work, a series of curcumin derivatives (1a–1h, 2a–2g, and 3a–3c) were synthesized for the suppression of castration‐resistant prostate cancer cells…”
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Novel construction of multifunctional photo-responsive and nucleic acid-triggered doxorubicin-releasing liposomes for cancer therapy by Liu, Xinxin, Meng, Liying, Wang, Zheyi, Yu, Zongjiang, Zhang, Chen, Liu, Limin, Coen, Zen, Yang, Zhongjun, Wu, Guanzhao

“…All-in-one nano theranostics integrating accurate diagnosis and combined therapy is promising for high-efficacy tumor treatment and receiving significant…”
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Enantioselective assembly of multi-layer 3D chirality by Wu, Guanzhao, Liu, Yangxue, Yang, Zhen, Jiang, Tao, Katakam, Nandakumar, Rouh, Hossein, Ma, Liulei, Tang, Yao, Ahmed, Sultan, Rahman, Anis U, Huang, Hongen, Unruh, Daniel, Li, Guigen

“…Abstract The first enantioselective assembly of sandwich-shaped organo molecules has been achieved by conducting dual asymmetric Suzuki-Miyaura couplings and…”
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Self-assembling nanoparticles of dually hydrophobic prodrugs constructed from camptothecin analogue for cancer therapy by Zhang, Yixuan, Yin, Ruijuan, Wu, Guanzhao, Yu, Mingming, Liu, Jiannan, Wang, Xueting, Liu, Xuemeng, Guan, Huashi, Yu, Rilei, Jiang, Tao

“…Nanomedicines have shown success in cancer therapy in recent years because of their excellent solubility in aqueous solution and drug accumulation through…”
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Multi-layer 3D chirality: new synthesis, AIE and computational studies by Liu, Yangxue, Wu, Guanzhao, Yang, Zhen, Rouh, Hossein, Katakam, Nandakumar, Ahmed, Sultan, Unruh, Daniel, Cui, Zhonghua, Lischka, Hans, Li, Guigen

“…New synthesis of multi-layer 3D chiral molecules has been developed under novel conditions to give better outcomes. The aggregation-induced emission (AIE), UV…”
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Asymmetric Catalytic Approach to Multilayer 3D Chirality by Wu, Guanzhao, Liu, Yangxue, Rouh, Hossein, Ma, Liulei, Tang, Yao, Zhang, Sai, Zhou, Peng, Wang, Jia‐Ying, Jin, Shengzhou, Unruh, Daniel, Surowiec, Kazimierz, Ma, Yanzhang, Li, Guigen

“…The first asymmetric catalytic approach to multilayer 3D chirality has been achieved by using Suzuki‐Miyaura cross‐couplings. New chiral catalysts were…”
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Exploring the Relationship between Nicotinic Acetylcholine Receptor Ligand Size, Efficiency, Efficacy, and C‑Loop Opening by Ma, Qianyun, Tae, Han-Shen, Wu, Guanzhao, Jiang, Tao, Yu, Rilei

“…Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels mediating fundamental physiological activities in the nervous system and have become…”
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Front Cover: Asymmetric Catalytic Approach to Multilayer 3D Chirality (Chem. Eur. J. 30/2021) by Wu, Guanzhao, Liu, Yangxue, Rouh, Hossein, Ma, Liulei, Tang, Yao, Zhang, Sai, Zhou, Peng, Wang, Jia‐Ying, Jin, Shengzhou, Unruh, Daniel, Surowiec, Kazimierz, Ma, Yanzhang, Li, Guigen

“…Chirality has existed in nature from the early stages of life on Earth. A new form of chirality, multilayer 3D chirality, has been established involving nearly…”
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Asymmetric Catalytic Approach to Multilayer 3D Chirality by Wu, Guanzhao, Liu, Yangxue, Rouh, Hossein, Ma, Liulei, Tang, Yao, Zhang, Sai, Zhou, Peng, Wang, Jia‐Ying, Jin, Shengzhou, Unruh, Daniel, Surowiec, Kazimierz, Ma, Yanzhang, Li, Guigen

“…Invited for the cover of this issue is Guigen Li and co‐workers at Texas Tech University and Nanjing University. The cover artwork shows that chirality…”
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Synthesis of Diastereoenriched α‐Aminomethyl Enaminones via a Brønsted Acid‐Catalyzed Asymmetric aza‐Baylis‐Hillman Reaction of Chiral N‐Phosphonyl Imines by Liu, Yangxue, Ahmed, Sultan, Qin, Xiao‐Yan, Rouh, Hossein, Wu, Guanzhao, Li, Guigen, Jiang, Bo

“…An effective chiral GAP methodology for preparing α‐aminomethyl enaminones through a (R)‐CSA‐catalyzed asymmetric aza‐Baylis‐Hillman reaction is reported…”
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