Search Results - "Wu, Gongwei"

cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions by Sun, Linchong, Song, Libing, Wan, Qianfen, Wu, Gongwei, Li, Xinghua, Wang, Yinghui, Wang, Jin, Liu, Zhaoji, Zhong, Xiuying, He, Xiaoping, Shen, Shengqi, Pan, Xin, Li, Ailing, Wang, Yulan, Gao, Ping, Tang, Huiru, Zhang, Huafeng

“…Cancer cells are known to undergo metabolic reprogramming to sustain survival and rapid proliferation, however, it remains to be fully elucidated how oncogenic…”
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Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress by Huang, De, Li, Tingting, Wang, Lin, Zhang, Long, Yan, Ronghui, Li, Kui, Xing, Songge, Wu, Gongwei, Hu, Lan, Jia, Weidong, Lin, Sheng-Cai, Dang, Chi V, Song, Libing, Gao, Ping, Zhang, Huafeng

“…Cancer cells are known for their capacity to rewire metabolic pathways to support survival and proliferation under various stress conditions. Ketone bodies,…”
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Intercalation-Driven Formation of siRNA Nanogels for Cancer Therapy by Huang, Xiangang, Wu, Gongwei, Liu, Chuang, Hua, Xianwu, Tang, Zhongmin, Xiao, Yufen, Chen, Wei, Zhou, Jun, Kong, Na, Huang, Peng, Shi, Jinjun, Tao, Wei

“…RNA interference (RNAi) is a powerful approach in the treatment of various diseases including cancers. The clinical translation of small interfering RNA…”
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Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1 by Ma, Xiaoyu, Li, Chenchen, Sun, Linchong, Huang, De, Li, Tingting, He, Xiaoping, Wu, Gongwei, Yang, Zheng, Zhong, Xiuying, Song, Libing, Gao, Ping, Zhang, Huafeng

“…Aberrant expression of Lin28 and let-7 has been observed in many human malignancies. However, its functions and underlying mechanisms remain largely elusive…”
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Epigenetic regulation of CD38/CD48 by KDM6A mediates NK cell response in multiple myeloma by Liu, Jiye, Xing, Lijie, Li, Jiang, Wen, Kenneth, Liu, Ning, Liu, Yuntong, Wu, Gongwei, Wang, Su, Ogiya, Daisuke, Song, Tian-Yu, Kurata, Keiji, Penailillo, Johany, Morelli, Eugenio, Wang, Tingjian, Hong, Xiaoning, Gulla, Annamaria, Tai, Yu-Tzu, Munshi, Nikhil, Richardson, Paul, Carrasco, Ruben, Hideshima, Teru, Anderson, Kenneth C.

“…Anti-CD38 monoclonal antibodies like Daratumumab (Dara) are effective in multiple myeloma (MM); however, drug resistance ultimately occurs and the mechanisms…”
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LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling by Gao, Yijun, Xiao, Qian, Ma, HuiMin, Li, Li, Liu, Jun, Feng, Yan, Fang, Zhaoyuan, Wu, Jing, Han, Xiangkun, Zhang, Junhua, Sun, Yihua, Wu, Gongwei, Padera, Robert, Chen, Haiquan, Wong, Kwok-kin, Ge, Gaoxiang, Ji, Hongbin, Johnson, Bruce E.

“…LKB1 loss-of-function mutations, observed in ∼30% of human lung adenocarcinomas, contribute significantly to lung cancer malignancy progression. We show that…”
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Menin enhances c-Myc-mediated transcription to promote cancer progression by Wu, Gongwei, Yuan, Mengqiu, Shen, Shengqi, Ma, Xiaoyu, Fang, Jingwen, Zhu, Lianbang, Sun, Linchong, Liu, Zhaoji, He, Xiaoping, Huang, De, Li, Tingting, Li, Chenchen, Wu, Jun, Hu, Xin, Li, Zhaoyong, Song, Libing, Qu, Kun, Zhang, Huafeng, Gao, Ping

“…Menin is an enigmatic protein that displays unique ability to either suppress or promote tumorigenesis in a context-dependent manner. The role for Menin to…”
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Glutathione‐Scavenging Nanoparticle‐Mediated PROTACs Delivery for Targeted Protein Degradation and Amplified Antitumor Effects by Liu, Hai‐Jun, Chen, Wei, Wu, Gongwei, Zhou, Jun, Liu, Chuang, Tang, Zhongmin, Huang, Xiangang, Gao, Jingjing, Xiao, Yufen, Kong, Na, Joshi, Nitin, Cao, Yihai, Abdi, Reza, Tao, Wei

“…PROteolysis TArgeting Chimeras (PROTACs) are an emerging class of promising therapeutic modalities that selectively degrade intracellular proteins of interest…”
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Correction: Author Correction: Menin enhances c-Myc-mediated transcription to promote cancer progression by Wu, Gongwei, Yuan, Mengqiu, Shen, Shengqi, Ma, Xiaoyu, Fang, Jingwen, Zhu, Lianbang, Sun, Linchong, Liu, Zhaoji, He, Xiaoping, Huang, De, Li, Tingting, Li, Chenchen, Wu, Jun, Hu, Xin, Li, Zhaoyong, Song, Libing, Qu, Kun, Zhang, Huafeng, Gao, Ping

“…Nature Communications 8: Article number: 15278 (2017); Published 5 May 2017; Updated 30 March 2018 The originally published version of this Article contained…”
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Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia by Zee, Barry M., Poels, Kamrine E., Yao, Cong-Hui, Kawabata, Kimihito C., Wu, Gongwei, Duy, Cihangir, Jacobus, William D., Senior, Elizabeth, Endress, Jennifer E., Jambhekar, Ashwini, Lovitch, Scott B., Ma, Jiexian, Dhall, Abhinav, Harris, Isaac S., Blanco, M. Andres, Sykes, David B., Licht, Jonathan D., Weinstock, David M., Melnick, Ari, Haigis, Marcia C., Michor, Franziska, Shi, Yang

“…A hallmark of acute myeloid leukemia (AML) is the inability of self-renewing malignant cells to mature into a non-dividing terminally differentiated state…”
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Preparation of copper nanoparticles on carbon nanotubes by electroless plating method by Xu, Cailu, Wu, Gongwei, Liu, Zheng, Wu, Dehai, Meek, Thomas T, Han, Qingyou

“…Densely distributed copper nanoparticles have been deposited on the surface of carbon nanotubes with a size of ∼10 nm by the electroless plating method. It has…”
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Arsenene Nanodots with Selective Killing Effects and their Low‐Dose Combination with ß‐Elemene for Cancer Therapy by Liu, Chuang, Sun, Shan, Feng, Qiang, Wu, Gongwei, Wu, Yiting, Kong, Na, Yu, Zhangsen, Yao, Junlie, Zhang, Xingcai, Chen, Wei, Tang, Zhongmin, Xiao, Yufen, Huang, Xiangang, Lv, Aman, Yao, Chenyang, Cheng, Haibo, Wu, Aiguo, Xie, Tian, Tao, Wei

“…Arsenical drugs have achieved hallmark success in treating patients with acute promyelocytic leukemia, but expanding their clinical utility to solid tumors has…”
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An effective way to lower catalyst content in well-aligned carbon nanotube films by Cao, Anyuan, Ci, Lijie, Wu, Gongwei, Wei, Binqing, Xu, Cailu, Liang, Ji, Wu, Dehai

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Intravesical delivery of KDM6A -mRNA via mucoadhesive nanoparticles inhibits the metastasis of bladder cancer by Kong, Na, Zhang, Ruonan, Wu, Gongwei, Sui, Xinbing, Wang, Junqing, Kim, Na Yoon, Blake, Sara, De, Diba, Xie, Tian, Cao, Yihai, Tao, Wei

“…Lysine-specific demethylase 6A (KDM6A), also named UTX, is frequently mutated in bladder cancer (BCa). Although known as a tumor suppressor, KDM6A's…”
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Hypoxia-Induced Suppression of Alternative Splicing of MBD2 Promotes Breast Cancer Metastasis via Activation of FZD1 by Liu, Zhaoji, Sun, Linchong, Cai, Yongping, Shen, Shengqi, Zhang, Tong, Wang, Nana, Wu, Gongwei, Ma, Wenhao, Li, Shi-Ting, Suo, Caixia, Hao, Yijie, Jia, Wei-Dong, Semenza, Gregg L, Gao, Ping, Zhang, Huafeng

“…Metastasis is responsible for the majority of breast cancer-related deaths, however, the mechanisms underlying metastasis in this disease remain largely…”
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MYC promotes cancer progression by modulating m6A modifications to suppress target gene translation by Wu, Gongwei, Suo, Caixia, Yang, Ying, Shen, Shengqi, Sun, Linchong, Li, Shi-Ting, Zhou, Yingli, Yang, Dongdong, Wang, Yan, Cai, Yongping, Wang, Nana, Zhang, Huafeng, Yang, Yun-Gui, Cao, Jie, Gao, Ping

“…The MYC oncoprotein activates and represses gene expression in a transcription-dependent or transcription-independent manner. Modification of mRNA emerges as a…”
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ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas by Jiang, Baishan, Weinstock, David M, Donovan, Katherine A, Sun, Hong-Wei, Wolfe, Ashley, Amaka, Sam, Donaldson, Nicholas L, Wu, Gongwei, Jiang, Yuan, Wilcox, Ryan A, Fischer, Eric S, Gray, Nathanael S, Wu, Wenchao

“…Interleukin (IL)-2-inducible T cell kinase (ITK) is essential for T cell receptor (TCR) signaling and plays an integral role in T cell proliferation and…”
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Arsenene Nanodots with Selective Killing Effects and their Low‐Dose Combination with ß‐Elemene for Cancer Therapy (Adv. Mater. 37/2021) by Liu, Chuang, Sun, Shan, Feng, Qiang, Wu, Gongwei, Wu, Yiting, Kong, Na, Yu, Zhangsen, Yao, Junlie, Zhang, Xingcai, Chen, Wei, Tang, Zhongmin, Xiao, Yufen, Huang, Xiangang, Lv, Aman, Yao, Chenyang, Cheng, Haibo, Wu, Aiguo, Xie, Tian, Tao, Wei

“…Arsenical Drugs In article number 2102054, Aiguo Wu, Tian Xie, Wei Tao, and co‐workers reveal PEGylated arsenene nanodots (AsNDs@PEG) with high monoelemental…”
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Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1 by Wu, Wenchao, Nelson, Geoffrey M., Koch, Raphael, Donovan, Katherine A., Nowak, Radosław P., Heavican-Foral, Tayla B., Nirmal, Ajit J., Liu, Huiyun, Yang, Lei, Duffy, Jessica, Powers, Foster, Stevenson, Kristen E., Jones, Marcus Kenneth, Ng, Samuel Y., Wu, Gongwei, Jain, Salvia, Xu, Ran, Amaka, Sam, Trevisani, Christopher, Donaldson, Nicholas L., Hagner, Patrick R., de Leval, Laurence, Gaulard, Philippe, Iqbal, Javeed, Thakurta, Anjan, Fischer, Eric S., Adelman, Karen, Weinstock, David M.

“…Immunomodulatory (IMiD) agents like lenalidomide and pomalidomide induce the recruitment of IKZF1 and other targets to the CRL4CRBN E3 ubiquitin ligase,…”
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MYC promotes cancer progression by modulating m 6 A modifications to suppress target gene translation by Wu, Gongwei, Suo, Caixia, Yang, Ying, Shen, Shengqi, Sun, Linchong, Li, Shi-Ting, Zhou, Yingli, Yang, Dongdong, Wang, Yan, Cai, Yongping, Wang, Nana, Zhang, Huafeng, Yang, Yun-Gui, Cao, Jie, Gao, Ping

“…The MYC oncoprotein activates and represses gene expression in a transcription-dependent or transcription-independent manner. Modification of mRNA emerges as a…”
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