Search Results - "Wu, Gencheng"

Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors by Yue, Na, Huang, Huijie, Zhu, Xiaocang, Han, Qiuqin, Wang, Yalin, Li, Bing, Liu, Qiong, Wu, Gencheng, Zhang, Yuqiu, Yu, Jin

“…In recent years, proinflammatory cytokine interleukin-1β (IL-1β) was considered to play a critical role in the pathogenesis of depression. In addition, P2X7…”
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δ-Opioid receptor activation rescues the functional TrkB receptor and protects the brain from ischemia-reperfusion injury in the rat by Tian, Xuesong, Guo, Jingchun, Zhu, Min, Li, Minwei, Wu, Gencheng, Xia, Ying

“…δ-opioid receptor (DOR) activation reduced brain ischemic infarction and attenuated neurological deficits, while DOR inhibition aggravated the ischemic damage…”
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Electroacupuncture increased cerebral blood flow and reduced ischemic brain injury: dependence on stimulation intensity and frequency by Zhou, Fei, Guo, Jingchun, Cheng, Jieshi, Wu, Gencheng, Xia, Ying

“…Stroke causes ischemic brain injury and is a leading cause of neurological disability and death. There is, however, no promising therapy to protect the brain…”
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Inhibition of Spinal Interlukin-33/ST2 Signaling and Downstream ERK and JNK Pathways in Electroacupuncture Analgesia in Formalin Mice by Han, Ping, Liu, Shenbin, Zhang, Mengting, Zhao, Jing, Wang, Yanqing, Wu, Gencheng, Mi, Wenli

“…Although acupuncture is widely used to manage pain, it remains highly controversial, largely due to the lack of a clear mechanism for its benefits. Here, we…”
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Electroacupuncture Alleviates Surgical Trauma-Induced Hypothalamus Pituitary Adrenal Axis Hyperactivity Via microRNA-142 by Zhu, Jing, Chen, Zhejun, Meng, Zehui, Ju, Minda, Zhang, Mizhen, Wu, Gencheng, Guo, Haidong, Tian, Zhanzhuang

“…Electroacupuncture (EA) could improve the hyperactivity of the hypothalamus pituitary adrenal (HPA) axis induced by hepatectomy. However, its underlying…”
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Huperzine A ameliorates experimental autoimmune encephalomyelitis via the suppression of T cell-mediated neuronal inflammation in mice by Wang, Jun, Chen, Fu, Zheng, Peng, Deng, Weijuan, Yuan, Jia, Peng, Bo, Wang, Ruochen, Liu, Wenjun, Zhao, Hui, Wang, Yanqing, Wu, Gencheng

“…Huperzine A (HupA), a sesquiterpene alkaloid and a potent and reversible inhibitor of acetylcholinesterase, possesses potential anti-inflammatory properties…”
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Neuroimmune modulation following traumatic stress in rats: evidence for an immunoregulatory cascade mediated by c-Src, miRNA222 and PAK1 by Zhao, Hui, Yao, Ranran, Cao, Xiaoding, Wu, Gencheng

“…Neuroimmune modulation following traumatic stress is accompanied by cortical upregulation of c-Src expression, but the mechanistic details of the potential…”
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The regulation of nitric oxide synthase isoform expression in mouse and human fallopian tubes: potential insights for ectopic pregnancy by Hu, Junting, Ma, Shulan, Zou, Sien, Li, Xin, Cui, Peng, Weijdegård, Birgitta, Wu, Gencheng, Shao, Ruijin, Billig, Håkan, Feng, Yi

“…Nitric oxide (NO) is highly unstable and has a half-life of seconds in buffer solutions. It is synthesized by NO-synthase (NOS), which has been found to exist…”
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Age-Dependent Neuroimmune Modulation of IGF-1R in the Traumatic Mice by Zhao, Hui, Zhao, Xiaocong, Cao, Xiaoding, Wu, Gencheng

“…Age-dependent neuroimmune modulation following traumatic stress is accompanied by discordant upregulation of Fyn signaling in the frontal cortex, but the…”
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Neuron-glial cell communication in the traumatic stress-induced immunomodulation by Zhao, Hui, Xiao, Sheng, Kong, Xiaoyan, Wang, Jun, Cao, Xiaoding, Gencheng, Wu, Loh, Horace H., Law, Ping-Yee

“…We have previously reported that neuron and glia could collaboratively govern the immunomodulation in traumatic rats. Herein, we characterized the sequential…”
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Molecular characteristics and formation mechanisms of biogenic secondary organic aerosols in the mountainous background atmosphere of southern China by Zhang, Shenyang, Gong, Daocheng, Wu, Gengchen, Li, Yanlei, Ding, Yaozhou, Wang, Boguang, Wang, Hao

“…Biogenic secondary organic aerosols (BSOA) play a crucial role in atmospheric chemistry, with significant implications for air quality and human health…”
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miR-34b attenuates trauma-induced anxiety-like behavior by targeting CRHR1 by Zhu, Jing, Chen, Zhejun, Tian, Jinxing, Meng, Zehui, Ju, Mingda, Wu, Gencheng, Tian, Zhanzhuang

“…Exposure to trauma is a potential contributor to anxiety; however, the molecular mechanisms responsible for trauma-induced anxiety require further…”
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Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance by Zhu, Keying, Sun, Jingxian, Kang, Zheng, Zou, Zaofeng, Wu, Gencheng, Wang, Jun

“…Promoting remyelination is crucial for patients with demyelinating diseases including multiple sclerosis. However, it is still a circuitous conundrum finding a…”
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EGFR dependent subcellular communication was responsible for morphine mediated AC superactivation by Zhao, Hui, Wu, Gencheng, Cao, Xiaoding

“…Compensatory adenylyl cyclase (AC) superactivation has been postulated to be responsible for the development of morphine tolerance and dependence, the…”
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Resiliency to social defeat stress relates to the inter-strain social interaction and is influenced by season variation by Han, Qiuqin, Yang, Liu, Liu, Yan, Lv, Ning, Yu, Jin, Wu, Gencheng, Zhang, Yuqiu

“…Exposure to social defeat (SD) stress exerts social avoidance and depressive disorders. Little is known about the relationship between resiliency to stressors…”
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Repurposing of omeprazole for oligodendrocyte differentiation and remyelination by Zhu, Keying, Sun, Jingxian, Kang, Zheng, Zou, Zaofeng, Wu, Xi, Wang, Yanqing, Wu, Gencheng, Harris, Robert A., Wang, Jun

“…•The proton pump inhibitor omeprazole (OME) shows pro-remyelination property from Connectivity Map-based screening.•OME promotes differentiation of…”
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Effect of Electroacupuncture on Rat Ischemic Brain Injury : Importance of Stimulation Duration by Zhou, Fei, Guo, Jingchun, Cheng, Jieshi, Wu, Gencheng, Xia, Ying

“…We explored the optimal duration of electroacupuncture (EA) stimulation for protecting the brain against ischemic injury. The experiments were carried out in…”
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Effects of Chronic Electroacupuncture on Depression- and Anxiety-Like Behaviors in Rats with Chronic Neuropathic Pain by Wang, Yan-Qing, Yu, Jin, Jiang, Jian-Wei, Mi, Wen-Li, Wang, Zhi-Fu, Liu, Shen-Bin, Yue, Na, Li, Qian, Wu, Gencheng

“…Growing evidence indicates that chronic neuropathic pain is frequently accompanied by an array of psychiatric diseases, such as depression and anxiety…”
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Electroacupuncture facilitates remyelination by enhancing the clearance of degraded myelin debris in cuprizone-induced demyelinating model by Keying, Zhu, Zheng, Kang, Zaofeng, Zou, Gencheng, Wu, Jun, Wang

“…Abstract only…”
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A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells by Mao-Ying, Qi-Liang, Zhao, Jun, Dong, Zhi-Qiang, Wang, Jun, Yu, Jin, Yan, Min-Fen, Zhang, Yu-Qiu, Wu, Gen-Cheng, Wang, Yan-Qing

“…This study described a modified rat model of bone cancer pain. Syngeneic Walker 256 mammary gland carcinoma cells were injected into the tibia medullary cavity…”
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